Summaries & Associations of Study Results
TR-313 Mirex
Target Organs and Levels of Evidence
NTP Technical Report Number 313
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| MIREX 2385-85-5 |
03/04/87 | PESTICIDE | Dosed-Feed MR&FR:0,0.1,1,10,25, 50 (2ND STUDY) FR:0, 50,100 PPM/52 PER GROUP | Frederick Cancer Research Facility |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | LIVER: NEOPLASTIC NODULE 3/52 5/52 5/52 14/52 15/52 26/52 | |||
| ADRENAL GLAND MEDULLA: PHEOCHROMOCYTOMA 8/51 7/52 13/52 11/52 18/51 19/51 | ||||
| KIDNEY TRANSITIONAL CELL: PAPILLOMA 0/51 0/51 0/52 0/52 1/51 3/52 | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CYTOMEGALY; FATTY METAMORPHOSIS; ANGIECTASIS; NECROSIS | |||
| FR: CLEAR EVIDENCE | LIVER: NEOPLASTIC NODULE 2/52 23/52 30/52 | |||
| HEMATOPOIETIC SYSTEM: LEUKEMIA 6/52 9/52 14/52 | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CYTOMEGALY; FATTY METAMORPHOSIS; NECROSIS | |||
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