The National Gene Vector Laboratories (NGVL) was a gene therapy manufacturing and toxicology resource previously sponsored by the National Center for Research Resources, NIH. The program has been discontinued and is no longer offering manufacturing or toxicology services.

While vector production and toxicology studies are no longer supported, the NCRR has created a new program to assist gene therapy investigators, the National Gene Vector Biorepository (www.ngvbcc.org). The NGVB maintains a number of resources previously associated with the NGVL, including the NGVL Pharmacology/Toxicology Database and SeqMap bioinformatics tool for insertion site analysis. The NGVB now offers a variety of archiving services, educational resources, and a reagent repository.

The NGVB Coordinating Center is located in the Department of Medical and Molecular Genetics at the Indiana University School of Medicine, the same site as the previous NGVL Coordinating Center. If you have previously obtained NGVL support and have questions or concerns, please contact Lorraine Matheson lrubin at iupui dot edu or visit the NGVB website (www.ngvbcc.org) for alternative methods of contacting us!