Summary Report of the Technical Workshop on Issues Associated with Considering Developmental Changes in Behavior and Anatomy When Assessing Exposure to Children
Federal Register Notices
Contact
- Technical Information Staff
- by phone at: 703-347-8561
- by fax at: 703-347-8691
- by email at: nceadc.comment@epa.gov
- by fax at: 703-347-8691
An Agency workgroup convened under the auspices of the RAF has been exploring children's exposure assessment issues. This workgroup has concluded that a major issue facing Agency assessors is how to consider age-related changes in behavior and physiology when preparing exposure assessments for children. Children's behavior changes over time in ways that can have an important impact on exposure. Further, children's physiology changes over time in ways that can impact both their exposures and their susceptibility to certain health effects. There
are two aspects to these physiological changes. First, there are anatomical changes resulting from physical growth. Second, there are changes in pharmacokinetics and pharmacodynamics that affect the absorption, distribution, excretion and effects of environmental contaminants.
The Agency is examining the pharmacokinetic/ pharmacodynamic changes in children through other efforts and future meetings on this topic are anticipated. The July 2000 workshop focused on incorporating age-related changes in behavior and anatomy into Agency exposure assessments.
Downloads/Related Links
- Summary Report (Not Including Appendices) (PDF) (NA pp, 174 KB, about PDF)
- Report Appendices a, B, C & D (PDF) (NA pp, 697 KB, about PDF)
- Report Appendix H (PDF) (NA pp, 773 KB, about PDF)
- Report Appendix F (PDF) (NA pp, 16 KB, about PDF)
- Report Appendix G (PDF) (NA pp, 94 KB, about PDF)
- Report Appendix E (PDF) (NA pp, 2 MB, about PDF)
Citation