Title: Small Business Innovation Research
to Improve the Chemistry and Targeted Delivery of RNAi Molecules
Program
Announcement (PA) Number: PA-06-003 (SBIR [R43/R44])
Program
Announcement (PA) Number: PA-06-004 (STTR [R41/R42])
Purpose. The participating institutes of the National Institutes
of Health invite the small business community to apply cutting
edge-technology to develop new approaches and chemical modifications
that will increase the long term stability, delivery and targeting
of siRNAs in cells and tissues for laboratory and therapeutic
applications.
Expiration Date: now January 8, 2008
Title: Integration of Heterogeneous Data Sources
Program
Announcement (PA) Number: PA-06-010 (STTR [R41/R42])
Program
Announcement (PA) Number: PA-06-011 (SBIR [R43/R44])
Purpose. This FOA invites small businesses to develop innovative
software for addressing the integration of distributed cross-disciplinary
data sources into coherent knowledge bases for biomedical
research. Federating such data sources requires solving
a large number of technical, scientific, financial, social
and legal issues, and new tools are needed for aiding in
almost every aspect of this problem. Applications are expected
to describe at least one biomedical research problem that
will benefit from the proposed tool or tool set, as well
as to describe how the approach will scale when applied
to additional data sources and/or to other biomedical problems.
A clear description should be provided of how the impact
of these tools on biomedical research will be measured.
Finally, a reasonable mechanism for maintenance and expansion
of the software as well as integration with existing solutions
should be carefully outlined.
Expiration Date: now January 8, 2008
Title: Manufacturing Processes of Medical, Dental,
and Biological Technologies
Program
Announcement (PA) Number: PA-06-012 (STTR [R41/R42])
Program
Announcement (PA) Number: PA-06-013 (SBIR [R43/R44])
Purpose. On February 26, 2004, Executive Order 13329 (http://a257.g.akamaitech.net/7/257/2422/14mar20010800/edocket.access.gpo.gov/2004/pdf/04-4436.pdf)
was signed by President George W. Bush requiring SBIR/STTR
agencies, to the extent permitted by law and in a manner consistent
with the mission of the Department, to give high priority
within the SBIR and STTR programs to manufacturing-related
research and development (R&D). In response to this Executive
Order, NIH is expanding its focus by encouraging eligible
United States small business concerns to submit SBIR Phase
I, Phase II, and Fast-Track grant applications whose biomedical
research is related to advanced processing, manufacturing
processes, equipment and systems, and manufacturing workforce
skills and protection.
Expiration Date: September 8, 2008
Title: Bioengineering Nanotechnology Initiative
Program
Announcement (PA) Number: PA-06-008 (STTR [R41/R42])
Program
Announcement (PA) Number: PA-06-009 (SBIR [R43/R44])
Purpose. This Funding Opportunity Announcement (FOA), issued
as an initiative of the trans-NIH Bioengineering Consortium
(BECON) on behalf of the participating Institutes and Centers,
invites grant applications for projects for developing and
applying nanotechnology to biomedicine. Nanotechnology is
defined as the creation of functional materials, devices
and systems through control of matter at the scale of 1
to 100 nanometers, and the exploitation of novel properties
and phenomena at the same scale. Nanotechnology is emerging
as a field critical for enabling essential breakthroughs
that may have tremendous potential for affecting biomedicine.
Moreover, nanotechnologies developed in the next several
years may well form the foundation of significant commercial
platforms that shift the paradigms of clinical applications
Expiration Date: September 8, 2008
Title: Directed stem Cell Differentiation for Cell
Based Therapies for Heart, Lung, Blood, and Aging Diseases
Program
Announcement (PA) Number: PA-06-124 (SBIR [R43/R44])
Program
Announcement (PA) Number: PA-06-125 (STTR [R41/R42])
Purpose. This funding opportunity announcement (FOA) solicits
grant applications to define the factors and mechanisms
controlling the differentiation of embryonic or adult stem
or progenitor cells, either in vitro or in vivo. It is designed
to stimulate new scientific advances in stem cell differentiation
including technology research that may not be hypothesis
driven. The long range goal of this program is the development
of methods to direct the differentiation or development
of stem cells along specific cell lineages to yield replacement
cells for clinical use, whether the replacement cells are
formed in vitro for delivery or formed in vivo in the tissue
or organ environment.
Expiration Date: September 8, 2008
Title: Innovations in Biomedical Computational
Science and Technology Initiative
Program
Announcement (PA) Number: PAR-07-160 (SBIR [R43/R44])
Program
Announcement (PA) Number: PAR-07-161 (STTR [R41/R42])
Purpose. This funding opportunity announcement (FOA) solicits
grant applications from small business concerns (SBCs) that
propose innovative research in biomedical computational science
and technology to promote the progress of biomedical research.
There exists an expanding need to speed the progress of biomedical
research through the power of computing to manage and analyze
data and to model biological processes. The NIH is interested
in promoting research and developments in biomedical computational
science and technology that will support rapid progress in
areas of scientific opportunity in biomedical research. As
defined here biomedical computing or biomedical information
science and technology includes database design, graphical
interfaces, querying approaches, data retrieval, data visualization
and manipulation, data integration through the development
of integrated analytical tools, and tools for electronic collaboration,
as well as computational research including the development
of structural, functional, integrative, and analytical models
and simulations.
Expiration Date: May 8, 2009
Title: New Approaches to Arrhythmia Detection and
Treatment
Program
Announcement (PA) Number: PA-07-031 (STTR [R41/R42])
Program
Announcement (PA) Number: PA-07-032 (SBIR [R43/R44])
Purpose. The funding opportunity announcement (FOA) solicits
grant applications from small business concerns (SBCs) that
propose innovative research to improve our ability to detect,
treat and prevent cardiac arrhythmias using new or improved
methods, tools, and technologies. Applications are invited
for the development and significant improvements of innovative
monitoring tools, diagnostic methods, and therapeutic approaches
for arrhythmia detection, treatment and prevention.
Expiration Date: December 6, 2009
Title: New Technology for Proteomics and Glycomics
Program
Announcement (PA) Number: PA-07-451 (SBIR [R43/R44])
Program
Announcement (PA) Number: PA-07-452 (STTR [R41/R42])
Purpose. Proteomics technologies and methods remain largely
inadequate, particularly with respect to quantitative and
real time measurements. This funding opportunity announcement
(FOA) solicits grant applications from small business concerns
(SBCs) that propose the development of broadly applicable
research tools that address the core technical challenges
in proteomics and glycomics. This includes but is not restricted
to robotics, sample preparation and pre-fractionation, analytical
separations, gel and array imaging, quantitation, mass spectrometry,
intelligent automated data acquisition, and improved informatics
technologies.
Expiration Date: August 6, 2010
Title: Bioengineering Approaches to Energy Balance
and Obesity
Program
Announcement (PA) Number: PA-07-435 (SBIR [R43/R44])
Program
Announcement (PA) Number: PA-07-436 (STTR [R41/R42])
Purpose: This funding opportunity will develop and validate
new and innovative bioengineering technology to address clinical
problems related to energy balance, intake, and expenditure.
Novel sensors, devices, imaging, and other approaches are
expected to be developed and evaluated by collaborating engineers,
physical scientists, and scientists from other relevant disciplines
with expertise in obesity and nutrition. The goal is to increase
the number of useful technologies and tools available to scientists
to facilitate their research in energy balance and health.
Eventually these research tools should facilitate therapeutic
advances and behavioral changes to address such problems as
weight control and obesity.
Expiration Date: August 6, 2010
