Testing Status of Agents at NTP
Chlorinated paraffins: C12, 60% chlorine
CASRN: 108171-26-2
Formula: C12-H19-CL7
Synonyms/Common Names:
- CERECLOR 54
- CHLOROWAX 500C
Known Uses:
ADDITIVE FOR EXTREME PRESSURE LUBRICANT; FLAME RETARDANT IN RUBBER, PLASTIC, AND PAINT
Short-Term Toxicity
- 14-Day (Gavage)
(C53587) Completed
- NTIS No. PB86-248101
(Peer Review 08/14/1985)
Citation: Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB86-248101
(Peer Review 08/14/1985)
- 13-Week (Gavage)
(C53587) Completed
- NTIS No. PB86-248101
(Peer Review 08/14/1985)
Citation: Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,313,5000, M: 0,469,7500 MG/KG/5 PER GROUP
- NTIS No. PB86-248101
(Peer Review 08/14/1985)
Long-Term Carcinogenicity
- 2-YEAR (Gavage)
(C53587) Report Complete
- TR-308 (NTIS No. PB86-248101)
(Peer Review 08/14/1985)
Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Clear Evidence
- Female Rats Clear Evidence
- Male Mice Clear Evidence
- Female Mice Clear Evidence
- Dose: R: 0,312,625, M: 0,125,250 MG/KG/50 PER GROUP
- TR-308 (NTIS No. PB86-248101)
(Peer Review 08/14/1985)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(132281) Completed
- Citation: Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- Mouse Lymphoma
(333321) Completed
- Positive
- Salmonella
(731132) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
- Negative
Web page last updated on November 24, 2008