14 January 2009

Letters

Large-scale pattern growth of graphene films for stretchable transparent electrodes

Keun Soo Kim, Yue Zhao, Houk Jang, Sang Yoon Lee, Jong Min Kim, Kwang S. Kim, Jong-Hyun Ahn, Philip Kim, Jae-Young Choi & Byung Hee Hong

doi:10.1038/nature07719

First paragraph | Full Text | PDF (1,215K) | Supplementary information

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA

Sebastian Leidel, Patrick G. A. Pedrioli, Tamara Bucher, Renée Brost, Michael Costanzo, Alexander Schmidt, Ruedi Aebersold, Charles Boone, Kay Hofmann & Matthias Peter

doi:10.1038/nature07643

First paragraph | Full Text | PDF (616K) | Supplementary information

Synaptic depression enables neuronal gain control

Jason S. Rothman, Laurence Cathala, Volker Steuber & R. Angus Silver

doi:10.1038/nature07604

First paragraph | Full Text | PDF (1,086K) | Supplementary information

11 January 2009

Article

Adaptive immune features of natural killer cells

Joseph C. Sun, Joshua N. Beilke & Lewis L. Lanier

doi:10.1038/nature07665

Abstract | Full Text | PDF (604K) | Supplementary information

Letters

Transcriptome sequencing to detect gene fusions in cancer

Christopher A. Maher, Chandan Kumar-Sinha, Xuhong Cao, Shanker Kalyana-Sundaram, Bo Han, Xiaojun Jing, Lee Sam, Terrence Barrette, Nallasivam Palanisamy & Arul M. Chinnaiyan

doi:10.1038/nature07638

First paragraph | Full Text | PDF (457K) | Supplementary information

Genetic architecture of mouse skin inflammation and tumour susceptibility

David A. Quigley, Minh D. To, Jesús Pérez-Losada, Facundo G. Pelorosso, Jian-Hua Mao, Hiroki Nagase, David G. Ginzinger & Allan Balmain

doi:10.1038/nature07683

First paragraph | Full Text | PDF (838K) | Supplementary information

07 January 2009

Article

Intersubunit coordination in a homomeric ring ATPase

Jeffrey R. Moffitt, Yann R. Chemla, K. Aathavan, Shelley Grimes, Paul J. Jardine, Dwight L. Anderson & Carlos Bustamante

doi:10.1038/nature07637

Abstract | Full Text | PDF (889K) | Supplementary information

Letter

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

Michael J. Chen, Tomomasa Yokomizo, Brandon M. Zeigler, Elaine Dzierzak & Nancy A. Speck

doi:10.1038/nature07619

First paragraph | Full Text | PDF (1,033K) | Supplementary information

04 January 2009

Letters

Ca²⁺/calmodulin regulates salicylic-acid-mediated plant immunity

Liqun Du, Gul S. Ali, Kayla A. Simons, Jingguo Hou, Tianbao Yang, A. S. N. Reddy & B. W. Poovaiah

doi:10.1038/nature07612

First paragraph | Full Text | PDF (965K) | Supplementary information

Deficiency of a -arrestin-2 signal complex contributes to insulin resistance

Bing Luan, Jian Zhao, Haiya Wu, Baoyu Duan, Guangwen Shu, Xiaoying Wang, Dangsheng Li, Weiping Jia, Jiuhong Kang & Gang Pei

doi:10.1038/nature07617

First paragraph | Full Text | PDF (530K) | Supplementary information

31 December 2008

Letters

Casein kinase 1 governs antigen-receptor-induced NF-B activation and human lymphoma cell survival

Nicolas Bidère, Vu N. Ngo, Jeansun Lee, Cailin Collins, Lixin Zheng, Fengyi Wan, R. Eric Davis, Georg Lenz, D. Eric Anderson, Damien Arnoult, Aimé Vazquez, Keiko Sakai, Jun Zhang, Zhaojing Meng, Timothy D. Veenstra, Louis M. Staudt & Michael J. Lenardo

doi:10.1038/nature07613

First paragraph | Full Text | PDF (700K) | Supplementary information

Pyrrolysyl-tRNA synthetase–tRNA^Pyl structure reveals the molecular basis of orthogonality

Kayo Nozawa, Patrick O'Donoghue, Sarath Gundllapalli, Yuhei Araiso, Ryuichiro Ishitani, Takuya Umehara, Dieter Söll & Osamu Nureki

doi:10.1038/nature07611

• PDB code

  • 2zni
  • 2znj

• 3D view

  • 2zni
  • 2znj

First paragraph | Full Text | PDF (975K) | Supplementary information

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

Fiona L. Scott, Boguslaw Stec, Cristina Pop, Magorzata K. Dobaczewska, JeongEun J. Lee, Edward Monosov, Howard Robinson, Guy S. Salvesen, Robert Schwarzenbacher & Stefan J. Riedl

doi:10.1038/nature07606

• PDB code

  • 3EZQ

• 3D view

  • 3EZQ

First paragraph | Full Text | PDF (752K) | Supplementary information

Calcium flickers steer cell migration

Chaoliang Wei, Xianhua Wang, Min Chen, Kunfu Ouyang, Long-Sheng Song & Heping Cheng

doi:10.1038/nature07577

First paragraph | Full Text | PDF (1,120K) | Supplementary information

21 December 2008

Letters

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

Christian Eggeling, Christian Ringemann, Rebecca Medda, Günter Schwarzmann, Konrad Sandhoff, Svetlana Polyakova, Vladimir N. Belov, Birka Hein, Claas von Middendorff, Andreas Schönle & Stefan W. Hell

doi:10.1038/nature07596

First paragraph | Full Text | PDF (724K) | Supplementary information

Nodal signalling is involved in left–right asymmetry in snails

Cristina Grande & Nipam H. Patel

doi:10.1038/nature07603

First paragraph | Full Text | PDF (1,595K) | Supplementary information

Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

Tijana Jovanovic-Talisman, Jaclyn Tetenbaum-Novatt, Anna Sophia McKenney, Anton Zilman, Reiner Peters, Michael P. Rout & Brian T. Chait

doi:10.1038/nature07600

First paragraph | Full Text | PDF (798K) | Supplementary information

A stress-responsive RNA switch regulates VEGFA expression

Partho Sarothi Ray, Jie Jia, Peng Yao, Mithu Majumder, Maria Hatzoglou & Paul L. Fox

doi:10.1038/nature07598

First paragraph | Full Text | PDF (1,017K) | Supplementary information

17 December 2008

Letters

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es, Marc van de Wetering, Harry Begthel, Maaike van den Born, Esther Danenberg, Alan R. Clarke, Owen J. Sansom & Hans Clevers

doi:10.1038/nature07602

First paragraph | Full Text | PDF (1,703K) | Supplementary information

The DNA-encoded nucleosome organization of a eukaryotic genome

Noam Kaplan, Irene K. Moore, Yvonne Fondufe-Mittendorf, Andrea J. Gossett, Desiree Tillo, Yair Field, Emily M. LeProust, Timothy R. Hughes, Jason D. Lieb, Jonathan Widom & Eran Segal

doi:10.1038/nature07667

First paragraph | Full Text | PDF (707K) | Supplementary information

Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80

Boxun Lu, Yanhua Su, Sudipto Das, Haikun Wang, Yan Wang, Jin Liu & Dejian Ren

doi:10.1038/nature07579

First paragraph | Full Text | PDF (527K) | Supplementary information

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

Liqin Zhu, Paul Gibson, D. Spencer Currle, Yiai Tong, Robert J. Richardson, Ildar T. Bayazitov, Helen Poppleton, Stanislav Zakharenko, David W. Ellison & Richard J. Gilbertson

doi:10.1038/nature07589

First paragraph | Full Text | PDF (1,095K) | Supplementary information

14 December 2008

Article

The unfolded protein response signals through high-order assembly of Ire1

Alexei V. Korennykh, Pascal F. Egea, Andrei A. Korostelev, Janet Finer-Moore, Chao Zhang, Kevan M. Shokat, Robert M. Stroud & Peter Walter

doi:10.1038/nature07661

• PDB code

  • 3FBV

• 3D view

  • 3FBV

Abstract | Full Text | PDF (1,346K) | Supplementary information

Letters

Messenger RNA targeting to endoplasmic reticulum stress signalling sites

Tomás Aragón, Eelco van Anken, David Pincus, Iana M. Serafimova, Alexei V. Korennykh, Claudia A. Rubio & Peter Walter

doi:10.1038/nature07641

First paragraph | Full Text | PDF (1,227K) | Supplementary information

RAD6–RAD18–RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light

Takashi Hishida, Yoshino Kubota, Antony M. Carr & Hiroshi Iwasaki

doi:10.1038/nature07580

First paragraph | Full Text | PDF (611K) | Supplementary information

Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans

Sakiko Honjoh, Takuya Yamamoto, Masaharu Uno & Eisuke Nishida

doi:10.1038/nature07583

First paragraph | Full Text | PDF (503K) | Supplementary information

Sleep and sensorimotor integration during early vocal learning in a songbird

Sylvan S. Shank & Daniel Margoliash

doi:10.1038/nature07615

First paragraph | Full Text | PDF (1,869K) | Supplementary information

10 December 2008

Letters

Endochondral ossification is required for haematopoietic stem-cell niche formation

Charles K. F. Chan, Ching-Cheng Chen, Cynthia A. Luppen, Jae-Beom Kim, Anthony T. DeBoer, Kevin Wei, Jill A. Helms, Calvin J. Kuo, Daniel L. Kraft & Irving L. Weissman

doi:10.1038/nature07547

First paragraph | Full Text | PDF (1,112K) | Supplementary information

Detoxification of sulphidic African shelf waters by blooming chemolithotrophs

Gaute Lavik, Torben Stührmann, Volker Brüchert, Anja Van der Plas, Volker Mohrholz, Phyllis Lam, Marc Mumann, Bernhard M. Fuchs, Rudolf Amann, Ulrich Lass & Marcel M. M. Kuypers

doi:10.1038/nature07588

First paragraph | Full Text | PDF (738K) | Supplementary information

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

Catherine D. Van Raamsdonk, Vladimir Bezrookove, Gary Green, Jürgen Bauer, Lona Gaugler, Joan M. O'Brien, Elizabeth M. Simpson, Gregory S. Barsh & Boris C. Bastian

doi:10.1038/nature07586

First paragraph | Full Text | PDF (794K) | Supplementary information

Enhancing SIV-specific immunity in vivo by PD-1 blockade

Vijayakumar Velu, Kehmia Titanji, Baogong Zhu, Sajid Husain, Annette Pladevega, Lilin Lai, Thomas H. Vanderford, Lakshmi Chennareddi, Guido Silvestri, Gordon J. Freeman, Rafi Ahmed & Rama Rao Amara

doi:10.1038/nature07662

First paragraph | Full Text | PDF (715K) | Supplementary information

07 December 2008

Letters

Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction

Dagmar Heuer, Anette Rejman Lipinski, Nikolaus Machuy, Alexander Karlas, Andrea Wehrens, Frank Siedler, Volker Brinkmann & Thomas F. Meyer

doi:10.1038/nature07578

First paragraph | Full Text | PDF (1,561K) | Supplementary information

ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development

Shigeru Oshima, Emre E. Turer, Joseph A. Callahan, Sophia Chai, Rommel Advincula, Julio Barrera, Nataliya Shifrin, Bettina Lee, Benjamin Yen, Tammy Woo, Barbara A. Malynn & Averil Ma

doi:10.1038/nature07575

First paragraph | Full Text | PDF (577K) | Supplementary information

Enterotoxigenic Escherichia coli EtpA mediates adhesion between flagella and host cells

Koushik Roy, George M. Hilliard, David J. Hamilton, Jiwen Luo, Marguerite M. Ostmann & James M. Fleckenstein

doi:10.1038/nature07568

First paragraph | Full Text | PDF (2,365K) | Supplementary information

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

Aurelien Trompette, Senad Divanovic, Alberto Visintin, Carine Blanchard, Rashmi S. Hegde, Rajat Madan, Peter S. Thorne, Marsha Wills-Karp, Theresa L. Gioannini, Jerry P. Weiss & Christopher L. Karp

doi:10.1038/nature07548

First paragraph | Full Text | PDF (621K) | Supplementary information

Counting RAD51 proteins disassembling from nucleoprotein filaments under tension

Joost van Mameren, Mauro Modesti, Roland Kanaar, Claire Wyman, Erwin J. G. Peterman & Gijs J. L. Wuite

doi:10.1038/nature07581

First paragraph | Full Text | PDF (448K) | Supplementary information

03 December 2008

Letter

A simple model of bipartite cooperation for ecological and organizational networks

Serguei Saavedra, Felix Reed-Tsochas & Brian Uzzi

doi:10.1038/nature07532

First paragraph | Full Text | PDF (363K) | Supplementary information

30 November 2008

Letters

Protein kinase R reveals an evolutionary model for defeating viral mimicry

Nels C. Elde, Stephanie J. Child, Adam P. Geballe & Harmit S. Malik

doi:10.1038/nature07529

First paragraph | Full Text | PDF (637K) | Supplementary information

Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus

Céline M. O'Gorman, Hubert T. Fuller & Paul S. Dyer

doi:10.1038/nature07528

First paragraph | Full Text | PDF (723K) | Supplementary information

A core gut microbiome in obese and lean twins

Peter J. Turnbaugh, Micah Hamady, Tanya Yatsunenko, Brandi L. Cantarel, Alexis Duncan, Ruth E. Ley, Mitchell L. Sogin, William J. Jones, Bruce A. Roe, Jason P. Affourtit, Michael Egholm, Bernard Henrissat, Andrew C. Heath, Rob Knight & Jeffrey I. Gordon

doi:10.1038/nature07540

First paragraph | Full Text | PDF (429K) | Supplementary information

26 November 2008

Letter

Ferritin is used for iron storage in bloom-forming marine pennate diatoms

Adrian Marchetti, Micaela S. Parker, Lauren P. Moccia, Ellen O. Lin, Angele L. Arrieta, Francois Ribalet, Michael E. P. Murphy, Maria T. Maldonado & E. Virginia Armbrust

doi:10.1038/nature07539

• PDB code

  • 3E6R
  • 3E6S

• 3D view

  • 3E6R
  • 3E6S

First paragraph | Full Text | PDF (476K) | Supplementary information

23 November 2008

Letter

Pulsed contractions of an actin–myosin network drive apical constriction

Adam C. Martin, Matthias Kaschube & Eric F. Wieschaus

doi:10.1038/nature07522

First paragraph | Full Text | PDF (1,295K) | Supplementary information

19 November 2008

Letter

Detecting influenza epidemics using search engine query data

Jeremy Ginsberg, Matthew H. Mohebbi, Rajan S. Patel, Lynnette Brammer, Mark S. Smolinski & Larry Brilliant

doi:10.1038/nature07634

First paragraph | Full Text | PDF (242K) | Supplementary information

05 November 2008

Letter

WNT11 acts as a directional cue to organize the elongation of early muscle fibres

Jérôme Gros, Olivier Serralbo & Christophe Marcelle

doi:10.1038/nature07564

First paragraph | Full Text | PDF (6,955K) | Supplementary information

02 November 2008

Letter

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

Marina Cella, Anja Fuchs, William Vermi, Fabio Facchetti, Karel Otero, Jochen K. M. Lennerz, Jason M. Doherty, Jason C. Mills & Marco Colonna

doi:10.1038/nature07537

First paragraph | Full Text | PDF (678K) | Supplementary information