Summaries & Associations of Study Results
TR-490 Glutaraldehyde
Target Organs and Levels of Evidence
NTP Technical Report Number 490
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| GLUTARALDEHYDE 111-30-8 |
10/30/98 | DISINFECTANT AND STERILIZING AGENT. EMBALMING FLUID. CHEMICAL INTERMEDIATE FOR ADHESIVES, ELECTRICAL PRODUCTS, TANNING SOFT LEATHERS (HSDB 1990). IN PHOTOGRAPHIC DEVELOPING, DENTAL MATERIALS. | Inhalation R: 0, 250, 500, OR 750 PPB; 50/SEX/GROUP M: 0, 62.5, 125, OR 250 PPB; 50/SEX/ GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: SQUAMOUS EPITHELIUM HYPERPLASIA; SQUAMOUS EPITHELIUM INFLAMMATION;RESPIRATORY EPITHELIUM HYPERPLASIA; RESPIRATORY EPITHELIUM INFLAMMATION; RESPIRATORY EPITHELIUM SQUAMOUS METAPLASIA; RESPIRATORY EPITHELIUM GOBLET CELL HYPERPLASIA; OLFACTORY EPITHELIUM HYALINE DEGENERATION | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: SQUAMOUS EPITHELIUM HYPERPLASIA; SQUAMOUS EPITHELIUM INFLAMMATION; RESPIRATORY EPITHELIUM HYPERPLASIA; RESPIRATORY EPITHELIUM INFLAMMATION; RESPIRATORY EPITHELIUM SQUAMOUS METAPLASIA; RESPIRATORY EPITHELIUM GOBLET CELL HYPERPLASIA; OLFACTORY EPITHELIUM HYALINE DEGENERATION | |||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: RESPIRATORY EPITHELIUM SQUAMOUS METAPLASIA | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: RESPIRATORY EPITHELIUM SQUAMOUS METAPLASIA; RESPIRATORY EPITHELIUM; HYALINE DEGENERATION; INFLAMMATION | |||
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