Testing Status of Agents at NTP
Vinyl toluene
CASRN: 25013-15-4
Formula: C9 H1O
Synonyms/Common Names:
- ETHENYLMETHYLBENZENE (9CI)
Known Uses:
PREPARING POLYESTER RESINS, MODIFIED ALKYL RESINS, AND DRYING OILS. IN ORTHOPEDIC CAST MATERIAL.
Short-Term Toxicity
- 14-Day (Inhalation)
(C56406) Completed
- NTIS No. PB90-260035
(Peer Review 11/20/1989)
Citation: Toxicology and Carcinogenesis Studies of Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32-35 para-isomer) (CAS No. 25013-15-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB90-260035
(Peer Review 11/20/1989)
- 13-Week (Inhalation)
(C56406) Completed
- NTIS No. PB90-260035
(Peer Review 11/20/1989)
Citation: Toxicology and Carcinogenesis Studies of Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32-35 para-isomer) (CAS No. 25013-15-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,25,1000, M: 0,10,160 PPM/10 PER GROUP
- NTIS No. PB90-260035
(Peer Review 11/20/1989)
Long-Term Carcinogenicity
- 2-YEAR (Inhalation)
(C56406) Report Complete
- TR-375 (NTIS No. PB90-260035)
(Peer Review 11/20/1989)
Toxicology and Carcinogenesis Studies of Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32-35 para-isomer) (CAS No. 25013-15-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats No Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R: 0,100,300, M: 0,10,25 PPM/50 PER GROUP
- TR-375 (NTIS No. PB90-260035)
(Peer Review 11/20/1989)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(390795) Completed
- Chromosome Aberation Negative
- Sister Chromatid Exchange Negative
- Mouse Lymphoma
(327329) Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Positive
- Salmonella
(527349) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
- Negative
Organ Systems Toxicity
- 5 CONS D Dominant Lethal (Intraperitoneal Injection)
(T0141) Completed
- M Rats: Sprague Dawley
- Dose: 500 MG/KF FOR 5 CONS D
Web page last updated on November 24, 2008