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Actinobacillus actinomycetemcomitans Search Results

Record: 1 of 1  
MiniMap tRNA-Pro-1 tRNA-Arg-3 IGR0850 IGR0849 IGR0847 IGR0845 IGR0846 IGR0844 IGR0848 IGR0843 AA01289 comD, - AA01298 comC, - AA01299 aroK,aroL,aroE, - AA01296 AA01287 folD, - AA01286 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 ssb, - AA01292 AA01289 comD, - AA01298 comC, - AA01299 aroK,aroL,aroE, - AA01296 AA01287 folD, - AA01286 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 ssb, - AA01292 AA01289 comC, - AA01299 aroK,aroL,aroE, - AA01296 folD, - AA01286 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 AA01288 dam, - AA01294 dam, - AA01294 AA01287 comD, - AA01298 AA01288 ssb, - AA01292


Gene ID:AA01292

DNA Molecule Name:
1  

GenBank ID:


Gene Name:
ssb  

Definition:
single-stranded DNA binding protein

Cellular Location:
Extracellular, Cytoplasm [Evidence]

Gene Start:
875967

Gene Stop:
876443

Gene Length:
477

Molecular Weight*:
20955

pI*:


Net Charge*:


EC:
 

Functional Class:
Replication; DNA replication, restriction, modification, recombination, and repair  

Gene Ontology:
Biological process
  GO:0006260    DNA replication

Molecular function
  GO:0003697    single-stranded DNA binding


Pathway: pathway table

Secondary Evidence:
Jarosik,G.P. and Hansen,E.J.
Cloning and sequencing of the Haemophilus influenzae ssb
gene encoding single-strand DNA-binding protein.
Gene 146(1):101-103, 1994.
PubMed: 8063092.

Meyer,R.R. and Laine,P.S.
The single-stranded DNA-binding protein of Escherichia coli.
Microbiol. Rev. 54(4)342-380, 1990.
PubMed: 2087220.

de Vries,J. and Wackernagel,W.
Cloning and sequencing of the Serratia marcescens gene
encoding a single-stranded DNA-binding protein (SSB) and its
promoter region. Gene 127(1):39-45, 1993.
PubMed: 8486286.

De Vries,J., Genschel,J., Urbanke,C., Thole,H. and
Wackernagel,W. The single-stranded-DNA-binding proteins
(SSB) of Proteus mirabilis and Serratia marcescens.
Eur. J. Biochem. 224(2):613-622,1994.
PubMed: 7925378

Comment:
See PVT1 or GI:10954410 for the plasmid version of this gene.

View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|52424640|ref|YP_087777.1|  single-strand DNA-binding prot...   229   3e-59
 gi|32029297|ref|ZP_00132340.1|  COG0629: Single-stranded DNA...   226   3e-58
 gi|152979537|ref|YP_001345166.1|  single-strand binding prot...   226   3e-58
 gi|15603815|ref|NP_246889.1|  single-strand DNA-binding prot...   219   5e-56
 gi|145635157|ref|ZP_01790862.1|  single-strand DNA-binding p...   216   3e-55
 gi|145640173|ref|ZP_01795757.1|  single-strand DNA-binding p...   215   5e-55
 gi|33152365|ref|NP_873718.1|  single-strand DNA-binding prot...   215   6e-55
 gi|145628571|ref|ZP_01784371.1|  single-strand DNA-binding p...   215   8e-55
 gi|148825471|ref|YP_001290224.1|  single-strand DNA-binding ...   214   1e-54
 gi|32029356|ref|ZP_00132389.1|  COG0629: Single-stranded DNA...   214   1e-54


InterPro Summary:  InterProScan

InterPro
IPR000424
Family
Single-strand binding protein/Primosomal replication protein n
PF00436 [4-108]T 1.2e-33 PF00436 SSB SSB
PS50935 [4-109]T 35.078 PS50935 SSB SSB
InterPro
IPR011344
Family
Single-strand binding protein
PTHR10302 [39-159]T 4.2e-35 PTHR10302 SINGLE-STRANDED DNA-BINDING PROTEIN, SSB SINGLE-STRANDED DNA-BINDING PROTEIN, SSB
TIGR00621 [2-159]T 4.6e-72 TIGR00621 ssb: single-strand binding protein ssb: single-strand binding protein
InterPro
IPR012340
Domain
Nucleic acid-binding, OB-fold
G3DSA:2.40.50.140 [4-144]T 2.4e-48 G3DSA:2.40.50.140 no description no description
noIPR
unintegrated
unintegrated
PIRSF002070 [4-149]T 1.8e-46 PIRSF002070 Single-strand binding protein Single-strand binding protein


COGS Summary:  COGS Search
No hits to the COGs database.
Blocks Summary:  Blocks Search

Significant hit ( 5.1e-49) to 3/3 blocks of the IPB000424 family, which is described as "Single-strand binding protein family". Interpro entry for IPR000424.
    IPB000424A    4-42    1.2e-23
    IPB000424B    68-90    2.2e-19
    IPB000424C    153-159    0.0034

 ProDom Summary:  Protein Domain Search

Residues 5 to 103 match (2e-09) PD:PD186605 which is described as DNA-BINDING DNA SINGLE-STRANDED PRECURSOR PEPTIDE MITOCHONDRIAL MITOCHONDRION REPLICATION TRANSIT MT-SSB

Paralogs:  Local Blast Search

AA01292 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search

Residues 4 to 109 (E-value = 1.7e-37) place AA01292 in the SSB family which is described as Single-strand binding protein family (PF00436)


 Top PDB Hits:


Gene Protein Sequence:
MAGVNKVIIVGNLGNDPEVRTMPNGEAVANITVATSESWNDKNTGERREV
TEWHRIVFYRRQAEVAGEYLRKGSKVYVEGRLRTRKWQDQNGQDRYTTEI
QGDVLQMLDSRADRQSGGNYTPTSQPSYPNQQQSAPRSAPASKPAAEAPM
DNFDDDIPF

Gene Nucleotide Sequence:  Sequence Viewer
ATGGCTGGAGTAAATAAAGTGATTATTGTCGGTAATTTAGGTAACGATCC
TGAAGTCCGCACCATGCCGAACGGCGAAGCCGTCGCCAATATCACCGTTG
CCACCAGTGAAAGCTGGAATGACAAAAACACCGGTGAACGCCGCGAAGTC
ACCGAATGGCACCGCATCGTATTTTATCGCCGCCAGGCGGAAGTGGCGGG
GGAATACCTGCGTAAAGGGTCTAAAGTCTATGTCGAAGGACGCTTAAGAA
CCCGTAAATGGCAGGATCAAAACGGTCAAGATCGCTACACCACCGAAATC
CAGGGCGACGTTTTACAAATGTTAGACAGCCGCGCCGATCGCCAATCCGG
CGGAAACTACACACCGACATCCCAACCAAGTTATCCAAACCAACAACAAA
GCGCCCCACGCAGTGCGCCGGCAAGTAAACCTGCCGCCGAAGCGCCGATG
GATAATTTTGATGATGATATTCCTTTT

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