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Emerging and re-emerging infectious diseases constitute one of the main challenges to medical science in the coming century. The exponential
growth of genetic studies over the last 20 years has greatly increased our knowledge of the transmission and pathogenicity of infectious
and parasitic diseases. Within ... click here for full Aims & Scope
Emerging and re-emerging infectious diseases constitute one of the main challenges to medical science in the coming century. The exponential
growth of genetic studies over the last 20 years has greatly increased our knowledge of the transmission and pathogenicity of infectious
and parasitic diseases. Within the field of human genetics, research has shown that susceptibility to many infectious diseases (including
leprosy, tuberculosis, malaria and schistosomiais) has a genetic basis. Furthermore, much is now known on the molecular epidemiology
and virulence of pathogenic agents, as well as their resistance to drugs, vaccines, and antibiotics. Such progress has been made despite
the formal and evolutionary genetics of many pathogenic agents remaining obscure. Equally, research on the genetics of disease vectors
has greatly improved our understanding of their systematics, has increased our capacity to identify target populations for control or
intervention, and has provided detailed information on the mechanisms of insecticide resistance.
However, the genetics of hosts, pathogens
and vectors have tended to develop as three separate fields of research. This artificial compartmentalisation is of concern due to our
growing appreciation of the strong coevolutionary interactions among hosts, pathogens and vectors. It is therefore highly desirable to
develop a unified synthetic approach: the "Integrated Genetic Epidemiology of Infectious Diseases" (IGEID). This will involve evaluation
of the respective impact of genetic diversity of hosts, pathogens and vectors on the transmission and severity of infectious diseases,
as well as their coevolutionary interactions. Infection, Genetics and Evolution - the Journal of Molecular Epidemiology and
Evolutionary Genetics in Infectious Diseases (MEEGID) - aims to be the forum for developing this IGEID approach. The journal welcomes
articles dealing with the genetics of hosts, pathogens and vectors in relation to infection and disease manifestation; preference will
be given to papers considering at least two of these interacting factors.
Additional information on the recently launched MEEGID
Society can be obtained by contacting Dr. Michel Tibayrenc at Michel.Tibayrenc@ird.fr
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Michel Tibayrenc
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