By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.
So far, 302 toxicological profiles have been published or are under development as “finals” or “drafts for public comment”; 289 profiles were published as finals; 130 profiles have been updated. Currently, 7profiles are being revised based on public comments received; 2 profiles are under development or review. These profiles cover more than 250 substances.
Toxicological profiles are developed in two stages:
(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Environmental Medicine.
(2) FINALS: After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles and the National Technical Information Service (NTIS) distributes them.
Congress requires ATSDR (1) to provide toxicological profiles to state health and environmental agencies and (2) to make them available to other interested parties. The Division of Toxicology and Environmental Medicine (DTEM) has a mailing list, which is updated and verified yearly, of groups and individuals who get free copies of both draft and final profiles; these include health professionals at federal, state, and local levels; academicians; nonprofit/environmental groups; members of the public involved with Superfund sites; and parties with special needs (considered case-by-case).
If you don’t qualify for free copies, you may request final profiles from NTIS for a fee.
NTIS distributes finalized toxicological profiles for a fee. For more information, contact
National Technical Information Service
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553 6847 or 703-605-6000
Web site: http://www.ntis.gov
To request a copy of the ToxProfiles™ CD-ROM, PHS, or ToxFAQs™ call 1-800-CDC-INFO (800-232-4636) or email your request to firstname.lastname@example.org.
For more information on the above listed publications, write
Division of Toxicology and Environmental Medicine,
Agency for Toxic Substances and Disease Registry
1600 Clifton Road, Mailstop F-32,
Atlanta, GA 30333
For more information
You may call the ATSDR toll free number at 1-800-CDC-INFO (800-232-4636) or 1-888-232-6348 (TTY) to get information about Division of Toxicology and Environmental Medicine programs.
ATSDR Internet home page via World Wide Web: http://www.atsdr.cdc.gov
The profiles, public health statements, ToxFAQs™ and other information are available on the Internet.
Finalized toxicological profiles by chemical with NTIS order number (Updates are in bold. Asterisks denote tox profiles funded by the Department of Defense)
The public comment period has ended and the profiles will be revised based on relevant public comments.
The CERCLA Set 22 profiles were made available for public comment on October 17, 2008. The public comment period will end on February 26, 2009.
The following set 22 profiles are currently under development or review.
Editor's note: CERCLA is the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (Superfund).
List updated on December 31, 2008