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Volume 2(8);  August 2004
Synopses
Deconstructing Genetic Contributions to Autoimmunity in Mouse Models
PLoS Biol. 2004 August; 2(8): e220. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020220.
PMCID: PMC509295
Identifying Genes Involved in Innate Immunity through RNAi
PLoS Biol. 2004 August; 2(8): e249. Published online 2004 June 22. doi: 10.1371/journal.pbio.0020249.
PMCID: PMC434154
Nicotine Keeps Leaf-Loving Herbivores at Bay
PLoS Biol. 2004 August; 2(8): e250. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020250.
PMCID: PMC509307
A New Role for a Synaptotagmin Protein in Calcium-Dependent Exocytosis
PLoS Biol. 2004 August; 2(8): e253. Published online 2004 June 29. doi: 10.1371/journal.pbio.0020253.
PMCID: PMC439008
Finding Mutations That Disrupt Cortical Development
PLoS Biol. 2004 August; 2(8): e254. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020254.
PMCID: PMC509308
A Protein Required for Fruitflies to Dispatch Wasp Parasites
PLoS Biol. 2004 August; 2(8): e255. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020255.
PMCID: PMC509309
Regenerating Lost Muscle: Msx1 to the Rescue
PLoS Biol. 2004 August; 2(8): e266. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020266.
PMCID: PMC509311
Yeast Use Dual Gain Controls to Amplify Protein Processing
PLoS Biol. 2004 August; 2(8): e269. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020269.
PMCID: PMC509313
Inhibition of the DNA Damage Pathway by a Telomere-Binding Protein
PLoS Biol. 2004 August; 2(8): e270. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020270.
PMCID: PMC509314
The Molecular Biology of Wound Healing
PLoS Biol. 2004 August; 2(8): e278. Published online 2004 July 20. doi: 10.1371/journal.pbio.0020278.
PMCID: PMC479044
Retrovirus Integration into the Human Genome
PLoS Biol. 2004 August; 2(8): e281. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020281.
PMCID: PMC509317
A Red-Blooded Transcription Factor
PLoS Biol. 2004 August; 2(8): e282. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020282.
PMCID: PMC509318
How the Brain Retrieves Forgotten Memories
PLoS Biol. 2004 August; 2(8): e283. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020283.
PMCID: PMC509319
Deterministic Tumor Evolution
PLoS Biol. 2004 August; 2(8): e284. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020284.
PMCID: PMC509320
Evolution's “Molecular Clock”: Not So Dependable After All?
PLoS Biol. 2004 August; 2(8): e287. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020287.
PMCID: PMC509321
Essay
Extinction, Slime, and Bottoms
Sean Nee
PLoS Biol. 2004 August; 2(8): e272. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020272.
PMCID: PMC509315
Feature
Opening a Window to the Autistic Brain
Kendall Powell
PLoS Biol. 2004 August; 2(8): e267. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020267.
PMCID: PMC509312
Book Review/Science in the Media
Mutants on the Small Screen
Jonathan Hodgkin
PLoS Biol. 2004 August; 2(8): e262. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020262.
PMCID: PMC509310
Journal Club
Grafting the Way to the Systemic Silencing Signal in Plants
Kriton Kalantidis
PLoS Biol. 2004 August; 2(8): e224. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020224.
PMCID: PMC509296
Primer
Unraveling the Molecular Basis for Regenerative Cellular Plasticity
Shannon J Odelberg
PLoS Biol. 2004 August; 2(8): e232. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020232.
PMCID: PMC509298
Mouse Models of Human Autoimmune Diseases: Essential Tools That Require the Proper Controls
Laurence Morel
PLoS Biol. 2004 August; 2(8): e241. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020241.
PMCID: PMC509303
Innate Immunity in Fruit Flies: A Textbook Example of Genomic Recycling
Shubha Govind and Ross H Nehm
PLoS Biol. 2004 August; 2(8): e276. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020276.
PMCID: PMC509316
Community Page
A New Model for Open Sharing: Massachusetts Institute of Technology's OpenCourseWare Initiative Makes a Difference
Anne H Margulies
PLoS Biol. 2004 August; 2(8): e200. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020200.
PMCID: PMC509291
Research Articles
Cellular Immune Response to Parasitization in Drosophila Requires the EBF Orthologue Collier
Michèle Crozatier, Jean-Michel Ubeda, Alain Vincent, and Marie Meister
PLoS Biol. 2004 August; 2(8): e196. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020196.
PMCID: PMC509289
Evidence for Widespread Convergent Evolution around Human Microsatellites
Edward J Vowles and William Amos
PLoS Biol. 2004 August; 2(8): e199. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020199.
PMCID: PMC509290
Functional Dissection of an Innate Immune Response by a Genome-Wide RNAi Screen
Edan Foley and Patrick H O'Farrell
PLoS Biol. 2004 August; 2(8): e203. Published online 2004 June 22. doi: 10.1371/journal.pbio.0020203.
PMCID: PMC434151
Nicotine's Defensive Function in Nature
Anke Steppuhn, Klaus Gase, Bernd Krock, Rayko Halitschke, and Ian T Baldwin
PLoS Biol. 2004 August; 2(8): e217. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020217.
PMCID: PMC509292
The Regenerative Plasticity of Isolated Urodele Myofibers and Its Dependence on Msx1
Anoop Kumar, Cristiana P Velloso, Yutaka Imokawa, and Jeremy P Brockes
PLoS Biol. 2004 August; 2(8): e218. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020218.
PMCID: PMC509293
A Focused and Efficient Genetic Screening Strategy in the Mouse: Identification of Mutations That Disrupt Cortical Development
Konstantinos Zarbalis, Scott R May, Yiguo Shen, Marc Ekker, John L. R Rubenstein, and Andrew S Peterson
PLoS Biol. 2004 August; 2(8): e219. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020219.
PMCID: PMC509294
Forgetting, Reminding, and Remembering: The Retrieval of Lost Spatial Memory
Livia de Hoz, Stephen J Martin, and Richard G. M Morris
PLoS Biol. 2004 August; 2(8): e225. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020225.
PMCID: PMC509297
Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis
Jyoti K Jaiswal, Sabyasachi Chakrabarti, Norma W Andrews, and Sanford M Simon
PLoS Biol. 2004 August; 2(8): e233. Published online 2004 June 29. doi: 10.1371/journal.pbio.0020233.
PMCID: PMC439782
Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences
Rick S Mitchell, Brett F Beitzel, Astrid R. W Schroder, Paul Shinn, Huaming Chen, Charles C Berry, Joseph R Ecker, and Frederic D Bushman
PLoS Biol. 2004 August; 2(8): e234. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020234.
PMCID: PMC509299
IRE1-Independent Gain Control of the Unfolded Protein Response
Jess H Leber, Sebastián Bernales, and Peter Walter
PLoS Biol. 2004 August; 2(8): e235. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020235.
PMCID: PMC509300
The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1γ, an Essential Regulator of Hematopoiesis
David G Ransom, Nathan Bahary, Knut Niss, David Traver, Caroline Burns, Nikolaus S Trede, Noelle Paffett-Lugassy, Walter J Saganic, C. Anthoney Lim, Candace Hersey, Yi Zhou, Bruce A Barut, Shuo Lin, Paul D Kingsley, James Palis, Stuart H Orkin, and Leonard I Zon
PLoS Biol. 2004 August; 2(8): e237. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020237.
PMCID: PMC509301
Cellular and Genetic Analysis of Wound Healing in Drosophila Larvae
Michael J Galko and Mark A Krasnow
PLoS Biol. 2004 August; 2(8): e239. Published online 2004 July 20. doi: 10.1371/journal.pbio.0020239.
PMCID: PMC479041
The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response
Jan Karlseder, Kristina Hoke, Olga K Mirzoeva, Christopher Bakkenist, Michael B Kastan, John H. J Petrini, and Titia de Lange
PLoS Biol. 2004 August; 2(8): e240. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020240.
PMCID: PMC509302
p19 Arf Suppresses Growth, Progression, and Metastasis of Hras-Driven Carcinomas through p53-Dependent and -Independent Pathways
Karen S Kelly-Spratt, Kay E Gurley, Yutaka Yasui, and Christopher J Kemp
PLoS Biol. 2004 August; 2(8): e242. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020242.
PMCID: PMC509304
Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice
Anne E Bygrave, Kirsten L Rose, Josefina Cortes-Hernandez, Joanna Warren, Robert J Rigby, H. Terence Cook, Mark J Walport, Timothy J Vyse, and Marina Botto
PLoS Biol. 2004 August; 2(8): e243. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020243.
PMCID: PMC509305
Gcn4p and Novel Upstream Activating Sequences Regulate Targets of the Unfolded Protein Response
Christopher K Patil, Hao Li, and Peter Walter
PLoS Biol. 2004 August; 2(8): e246. Published online 2004 August 17. doi: 10.1371/journal.pbio.0020246.
PMCID: PMC509306
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