Catherine Hill

Assistant Professor, Medical Entomology, Public Health
901 West State Street
West Lafayette , IN
47907-2089
 
Office Phone: 496-6157
Office Number: WSLR 130
Lab Number: WSLR 125
Office Phone: 496-1513
Fax: 496-1219
Email Address: hillca@purdue.edu


Education

PhDUniversity of Adelaide, Australia
BSUniversity of Adelaide, Australia


Professional Background

Postdoctoral Fellow - Eli Lilly and Company, Indianapolis, IN, 1998-2001

Postdoctoral Fellow - University of Notre Dame, Notre Dame, IN, 2001-2003


Professional Associations

American Association for the Advancement of Science
American Society of Tropical Medicine and Hygiene
Entomological Society of America


Research Interests

Vector Biology and Mosquito Functional GenomicsFunctional and pharmaco-genomics of GPCRs in the malaria vector mosquito Anopheles gambiae
Structure Based Drug DesigHomology modeling, structure based and rational drug design for novel invertebrate GPCRs
Mosquito VisionMolecular basis of mosquito vision and vision related behaviors
Tick GenomicsGenomics of the Lyme disease tick, Ixodes scapularis


Professional Activities

Member - Ixodes scapularis International Sequencing Committee, 2003 to present.

Committee Member - John V. Osmun Alumni Professional Achievement Award in Entomology, 2003 to present.

Invited Participant - Emerging Technologies for Vector Control: a Brainstorming Meeting, Bill and Melinda Gates Foundation, Seattle, WA, 26-28 February, 2003.

Ad hoc journal review for J. Med. Entomol., Gene, J. Chrom. Biol. B.


Research and Other Awards

Purdue University nominee for the Searle Scholars Program 2004

Society for Invertebrate Pathology International Conference Prize for Paper Presentation, 1997.

Participant Queens Trust For Young Australians National Forum Future Perspectives for Young Australians, Melbourne,Vic, 1996.

Society for Invertebrate Pathology Travel Scholarship, 1994.

Wool Research and Development Council, Ph.D. Scholarship, 1993-1996.

T.O. Browining Medal for Distinction in Entomology, 1992.

J.R. Barker Honors Scholarship, 1992.

Wool Research and Development Council National Undergraduate Studentship, 1991.


Extension/Outreach Activities

A number of emerging and re-emerging insect vectored diseases pose a threat to human and animal health in the United States. The aim of our extension program is to monitor and evaluate public health issues related to vector-borne diseases at a state, national and global level. Our extension responsibilities place an emphasis on the development of outreach and education programs to address concerns associated with diseases such as West Nile virus and Lyme disease. Please refer to the Purdue University Department of Entomology Extension website for further information and regular updates regarding vector borne diseases, the insects involved in disease transmission and recommended prevention and/or control measures.


Courses Taught

ENTM 525Medical and Veterinary Entomology


Available Positions

Postdoctoral FellowshipPOSTDOCTORAL FELOWSHIP

Genomics of Mosquito Vectors of Human Disease

The Department has an immediate opening for a postdoctoral fellowship to undertake functional genomic studies in the malaria vector mosquito, Anopheles gambiae. The successful candidate will participate as part of a research team to investigate the molecular characteristics and role of G protein-coupled receptors (GPCRs) in mosquito biological processes such as vision, hormonal regulation, longevity and stress response. Candidates will employ a range of pharmacogenomics techniques (including bioinformatics, microarrays, insect transgenesis, RNA interference and proteomics) to analyse these GPCRs for their potential as novel insecticidal targets and the development of innovative mosquito control strategies. Applicants should have a Ph.D. with substantial recent research experience, preferably in molecular biology, genomics, bioinformatics and DNA arrays. Competitive salary commensurate with experience.


Review of applications will begin January 1, 2005 and continue until a successful applicant is found


Please send curriculum vitae, addresses of three references and a letter describing research interests to:


Catherine A. Hill, Ph.D.
Department of Entomology
Purdue University
Smith Hall
901 W. State Street
West Lafayette, IN, 47907-2089
USA
hillca@purdue.edu



Requests for additional information regarding this research opportunity may be addressed to Dr. Hill (hillca@purdue.edu)



Purdue University is an equal opportunity/affirmative action employer.


Ixodes scapularis Genome Project

The International Ixodes scapularis Sequencing Committee has been established to initiate and oversee the sequencing of the first tick genome. This project will generate much needed information on the unique biology of ixodid ticks and will be an important platform for discovery efforts aimed at new tick control strategies. Please contact Catherine Hill for further information regarding this effort, the committee and its activities.


Selected Publications

Hill, C.A., Kafatos, F.C., Stansfield, S.K. and Collins, F.H. 2005. Arthropod-borne diseases: Vector control in the genomics era. Nature Reviews Microbiology. In Press.
Hill, C.A. and Wikel, S.K. 2005. The Ixodes scapularis genome project: an important opportunity for advancing tick research. Trends in Parasitology. In Press.
Collins, F.H. and Hill, C.A. 2005. The Anopheles gambiae genome. In "Molecular Approaches to Malaria". I.W. Sherman (Ed.). American Society for Microbiology. In Press.
Besansky, N.J., Hill, C.A. and Costantini, C. 2004. No accounting for taste: host preference in malaria vectors. Trends Parasitol. 20, 249-296
Lobo, N.F., Ton, L.Q., Hill, C.A., Emore, C., Romero-Severson, J., Hunt, G.J. and Collins, F.H. Genomic analysis in the sting 2 Quantitative Trait Locus for defensive behavior in the honey bee, Apis mellifera. Genome Research. Genome Research. 13, 2588-2593.
Hill, C.A. and Gutierrez, J.A. 2003. A method for extraction and analysis of high quality genomic DNA from ixodid ticks. Medical and Veterinary Entomology. 17, 224-227.
Hill, C.A., Fox, A.N., Pitts, R.J., Kent, L.B., Tan, P.L., Chrystal, M.A., Cravchik, A., Collins, F.H., Robertson, H.M. and L.J. Zweibel . 2002. G protein-coupled receptors in Anopheles gambiae. Science. Vol 298, 176-178.
Riehle, M.A., Garczynski, S.F., Crim, J.W., Hill, C.A. and M.R. Brown. 2002. Neuropeptides and peptide hormones in Anopheles gambiae. Science. Vol 298, 172-175.
Hill, C.A. and Gutierrez, J.A. 2000. Analysis of the expressed genome of the lone star tick, Amblyomma americanum using an EST approach. Microbial and Comparative Genomics. 5, 89-101.
Hill, C.A. and Pinnock, D.E. 1997. Histopathological effects of Bacillus thuringiensis on the alimentary canal of the sheep louse, Bovicola ovis. J. Invert. Pathol.