The Registry of Toxic Effects of Chemical Substances

Glutaraldehyde

RTECS #: MA2450000

CAS #: 111-30-8


UPDATE: August 2008 MW: 100.13 MF: C5H8O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. TUMORIGENIC DATA:
  6. ACUTE TOXICITY DATA:
  7. OTHER MULTIPLE DOSE DATA:
  8. REVIEWS:
  9. STANDARDS AND REGULATIONS:
  10. NIOSH DOCUMENTATION AND SURVEILLANCE:
  11. STATUS IN FEDERAL AGENCIES:
  12. REFERENCES:

SYNONYMS:

  1. 1,3 - Diformylpropane
  2. 1,5 - Pentanedial
  3. 1,5 - Pentanedione
  4. Aldehyd glutarowy (Polish)
  5. Cidex
  6. Glutaraldehyd (Czech)
  7. Glutaral
  1. Glutaraldehyde (ACGIH)
  2. Glutardialdehyde
  3. Glutaric dialdehyde
  4. NCI - C55425
  5. Potentiated acid glutaraldehyde
  6. Sonacide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
1 mg severe UCDS** 1/30/1970
eye
rabbit
250 µg/24 hour severe 85JCAE -,272,1986
eye
woman
200 ppb severe TOXID9 72,292,2003
skin
human
6 mg/3 day- intermittent severe 85DKA8 -,127,1977
skin
rabbit
13 mg open irritation test mild UCDS** 1/30/1970
skin
rabbit
2 mg/24 hour severe 85JCAE -,272,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis hamster ovary 160 µg/L ENMUDM 7,1,1985
DNA damage chicken leukocyte 8 pph CELLB5 5,45,1975
DNA damage hamster fibroblast 2,500 ppm SFCRAO 23,346,1970
DNA damage hamster fibroblast 20 µmol/L/1 hour MUREAV 649,146,2008
DNA damage human lymphocyte 10 µmol/L EMMUEG 17(Suppl 19),71,1991
DNA damage human leukocyte 5 µmol/L MUREAV 468,93,2000
DNA damage mammal (species unspecified) lymphocyte 2,500 µmol/L MUREAV 283,131,1992
DNA repair Bacillus subtilis 1 mg/L MUREAV 193,21,1988
mutation in microorganisms Escherichia coli 62,500 ng/plate (-enzymatic activation step) MUREAV 412,17,1998
mutation in microorganisms Salmonella typhimurium 500 nmol/L (+enzymatic activation step) MUREAV 148,25,1985
mutation in microorganisms Salmonella typhimurium 150 µg/plate (-enzymatic activation step) ENMUDM 5(Suppl 1),3,1983
mutation in microorganisms Salmonella typhimurium 0.5 mg/plate/48 hour (+enzymatic activation step) JAPTO* 22,45,2001
mutation in microorganisms Salmonella typhimurium 0.25 mg/plate/3 day (-enzymatic activation step) MUREAV 521,19,2002
mutation in microorganisms Salmonella typhimurium 25 µg/plate/72 hour (-enzymatic activation step) MUTAEX 15,495,2000
micronucleus test hamster fibroblast 10 µmol/L/1 hour MUREAV 649,146,2008
mutation in mammalian somatic cells mouse lymphocyte 8 mg/L EMMUEG 11,91,1988
other mutation test systems non-mammalian species other cell types 50 mmol/L ECREAL 95,233,1975
sister chromatid exchange hamster ovary 110 µg/L ENMUDM 7,1,1985
sister chromatid exchange hamster fibroblast 10 µmol/L/1 hour MUREAV 649,146,2008


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lowest published toxic dose: 50 gm/kg (6-15 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TJADAB 22,51,1980
oral
mouse
lowest published toxic dose: 8 gm/kg (6-15 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) TJADAB 22,51,1980
oral
rat
lowest published toxic dose: 875 mg/kg (35 day male) Reproductive: Paternal effects: Testes, epididymis, sperm duct

Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands
OYYAA2 12,11,1976
oral
rat
lowest published toxic dose: 4,370 mg/kg (35 day prior to copulation) Reproductive: Maternal effects: Uterus, cervix, vagina OYYAA2 12,11,1976
oral
rat
lowest published toxic dose: 1 gm/kg (6-15 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) TOLED5 63,147,1992
oral
rat
lowest published toxic dose: 5.3 gm/kg (84 day male/70 day prior to copulation-4 week after birth) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Other postnatal measures or effects

Reproductive: Effects on newborn: Delayed effects
JTEHD6 61,107,2000
oral
rat
lowest published toxic dose: 167.4 mg/kg (multigenerations) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Delayed effects
JTEHD6 61,107,2000
oral
rabbit
lowest published toxic dose: 585 mg/kg (7-19 day pregnant) Reproductive: Other effects on female

Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
NTIS** OTS0526410


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 2,912 mg/kg/104 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Blood: Leukemia

Tumorigenic: Increased incidence of tumors in susceptible strains
TXCYAC 175,177,2002
oral
rat
lowest published toxic dose: 2,912 mg/kg/104 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Blood: Leukemia

Tumorigenic: Increased incidence of tumors in susceptible strains
TXCYAC 175,177,2002


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): 480 mg/m3/4 hour N/R EPASR* 8EHQ-1290-1008
inhalation
rabbit
lowest published toxic concentration: 500 ppm Eye: Conjunctiva irritation

Lung, Thorax, or Respiration: Cough
VCVGK* -,404,1984
inhalation
woman
lowest published toxic concentration: 200 ppb Olfaction: Other olfaction effects TOXID9 72,292,2003
intraperitoneal
mouse
lethal dose (50 percent kill): 13,900 µg/kg N/R IYKEDH 10,232,1979
intraperitoneal
rat
lethal dose (50 percent kill): 17,900 µg/kg N/R IYKEDH 10,232,1979
intravenous
mouse
lethal dose (50 percent kill): 15,400 µg/kg N/R OYYAA2 19,503,1980
intravenous
rat
lethal dose (50 percent kill): 9,800 µg/kg N/R EPASR* 8EHQ-1290-1008
oral
duck
lethal dose (50 percent kill): 820 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)
NTIS** OTS0526410-1
oral
guinea pig
lethal dose (50 percent kill): 50 mg/kg Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Somnolence (general depressed activity)

Behavioral: Excitement
GISAAA 52(3),77,1987
oral
mouse
lethal dose (50 percent kill): 100 mg/kg N/R OYYAA2 19,503,1980
oral
mouse
lethal dose (50 percent kill): 231 mg/kg Lung, Thorax, or Respiration: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
VCVGK* -,404,1984
oral
rat
lethal dose (50 percent kill): 134 mg/kg N/R OYYAA2 19,503,1980
oral
rat
lethal dose (50 percent kill): 140 mg/kg Lung, Thorax, or Respiration: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
VCVGK* -,404,1984
subcutaneous
mouse
lethal dose (50 percent kill): >590 mg/kg N/R NIIRDN -,395,1995
subcutaneous
rat
lethal dose (50 percent kill): >750 mg/kg N/R NIIRDN -,395,1995
skin
mouse
lethal dose (50 percent kill): >5,840 mg/kg Skin: After systemic exposure: Dermatitis, other OYYAA2 12,11,1976
skin
mouse
lowest published toxic dose: 0.1 pph Immunological Including Allergic: Hypersensitivity delayed (multiple organ involvement) TOXID9 66,79,2002
skin
rat
lethal dose (50 percent kill): >2,500 mg/kg Skin: After systemic exposure: Dermatitis, other OYYAA2 12,11,1976
skin
rabbit
lethal dose (50 percent kill): 560 µL/kg N/R UCDS** 11/4/1971


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published toxic concentration: 16 ppm/6 hour/2 week- intermittent Olfaction: Other olfaction effects

Lung, Thorax, or Respiration: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTPTR* NIH-93-3348
inhalation
mouse
lowest published toxic concentration: 1,000 ppb/6 hour/13 week- intermittent Olfaction: Other olfaction effects

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTPTR* NIH-93-3348
inhalation
mouse
lowest published toxic concentration: 250 ppb/6 hour/2 year- intermittent Olfaction: Other olfaction effects

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TOXID9 48,341,1999
inhalation
rat
lowest published toxic concentration: 5 ppm/6 hour/2 week- intermittent Olfaction: Other olfaction effects

Lung, Thorax, or Respiration: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTPTR* NIH-93-3348
inhalation
rat
lowest published toxic concentration: 1,000 ppb/6 hour/13 week- intermittent Olfaction: Other olfaction effects

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTPTR* NIH-93-3348
inhalation
rat
lowest published toxic concentration: 500 ppb/6 hour/2 year- intermittent Olfaction: Other olfaction effects

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOXID9 48,341,1999
oral
rat
lowest published toxic dose: 12,376 mg/kg/2 year- continuous Kidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Changes in bladder weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TOXID9 15,203,1995
oral
rat
lowest published toxic dose: 54,600 µg/kg/26 week- intermittent Liver: Fatty liver degeneration

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase
GISAAA 52(3),77,1987
oral
rat
lowest published toxic dose: 11,410 mg/kg/7 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain NTIS** OTS0535072
oral
rat
lowest published toxic dose: 122.5 mg/kg/1 week- continuous Behavioral: Fluid intake JTEHD6 61,107,2000
oral
rat
lowest published toxic dose: 967 mg/kg/2 week- continuous Behavioral: Food intake (animal) JTEHD6 61,107,2000
oral
rat
lowest published toxic dose: 688.8 mg/kg/1 week- continuous Behavioral: Food intake (animal) JTEHD6 61,107,2000
oral
rat
lowest published toxic dose: 117.5 mg/kg/235 day- intermittent Endocrine: Changes in thymus weight

Blood: Normocytic anemia

Blood: Changes in other cell count (unspecified)
VCVGK* -,404,1994
oral
rat
lowest published toxic dose: 1,547 mg/kg/13 week- intermittent Kidney, Ureter, and Bladder: Urine volume decreased or anuria

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXCYAC 175,177,2002
oral
rat
lowest published toxic dose: 9,282 mg/kg/78 week- intermittent Kidney, Ureter, and Bladder: Urine volume decreased or anuria

Kidney, Ureter, and Bladder: Changes in kidney weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXCYAC 175,177,2002
subcutaneous
rat
lowest published toxic dose: 175 mg/kg/35 day- continuous Liver: Changes in liver weight

Endocrine: Changes in spleen weight

Blood: Normocytic anemia
OYYAA2 12,11,1976
skin
human
lowest published toxic concentration: 1 pph/48 hour- continuous Skin: After topical application: Dermatitis, allergic AJCDE* 13,177,2002


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 0.05 ppm (sen) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
DPIRDU 1(7),2,1981
TOXICOLOGY REVIEW
CRTXB2 22,143,1992
TOXICOLOGY REVIEW
JACTDZ 15,98,1996
TOXICOLOGY REVIEW
MUREAV 543,201,2003
TOXICOLOGY REVIEW
EMMUEG 39,69,2002
TOXICOLOGY REVIEW
MUREAV 589,136,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.2 ppm (0.7 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 0.2 mg/m3, short term exposure limit 0.82 mg/m3, JAN1993
Occupational Exposure Limit - DENMARK ceiling concentration 0.2 ppm (0.8 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND CEILING 0.1 ppm, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 ppm (0.4 mg/m3), VLE 0.2 ppm (0.8 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 0.21 mg/m3 (0.05 mL/m3) (airway and skin, sen), 2005
Occupational Exposure Limit - JAPAN Occupational Exposure Limit- continuous 0.03 ppm, sen, APR2007
Occupational Exposure Limit - KOREA ceiling concentration 0.2 ppm (0.7 mg/m3), 2006
Occupational Exposure Limit - MEXICO peak 0.2 ppm (0.7 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC- continuous 0.25 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND short term exposure limit 0.05 ppm, sen, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.2 ppm (0.8 mg/m3), JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN ceiling concentration 0.2 ppm (0.8 mg/m3), Sen, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.05 ppm (0.21 mg/m3),KZG- week 0.1 ppm (0.42 mg/m3), DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.05 ppm;
short term exposure limit 0.05 ppm (sen), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO GLUTARALDEHYDE-air ceiling concentration 0.2 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84349;
Number of Industries 11;
Total Number of Facilities 2,069;
Number of Occupations 25;
Total Number of Employees Exposed 12,954
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84349;
Number of Industries 35;
Total Number of Facilities 9,475;
Number of Occupations 63;
Total Number of Employees Exposed 367,330;
Total Number of Female Employees Exposed 265,564


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Negative: CHO gene mutation
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in leather tanning and in embalming fluids and as a germicide and crosslinking agent
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH CURRENT INTELLIGENCE BULLETIN #55, September 1991
NIOSH Analytical Method, 1994: Glutaraldehyde, 2532
NCI Carcinogenesis Studies (inhal);no evidence:mouse,rat
NTP Toxicity studies, RPT# TOX-25, October 2000
OSHA ANALYTICAL METHOD #ID-64


REFERENCES:

CODEN
REFERENCE

85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AJCDE* American Journal of Contact Dermatitis: Official Journal of the American Contact Dermatitis Society (Philadelphia, PA : W.B. Saunders, Harcourt Brace Jovanovich) V.1-14 1990-2003.
CELLB5 Cell (Cambridge, Mass.). (MIT Press, 28 Carleton St., Cambridge, MA 02142) V.1- 1974-
CRTXB2 CRC Critical Reviews in Toxicology. (CRC Press, Inc., 2000 Corporate Blvd., NW, Boca Raton, FL 33431) V.1- 1971-
DPIRDU Dangerous Properties of Industrial Materials Report. (Van Nostrand Reinhold, 115 Fifth Ave., New York, NY 10003) V.1- 1981-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950-
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG.
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
JAPTO* Journal of Applied Toxicology (John Wiley & Sons, Ltd., Oldlands Way Bognor Regis West Sussex, PO22 9SA England) V.1- 1981-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan)
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206-
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967-
SFCRAO Collection of Papers Presented at the Annual Symposium on Fundamental Cancer Research. (Baltimore, MD) V.1-29, 1946-76. For publisher information, see AFCPDR.
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used in leather tanning and in embalming fluids and as a germicide and crosslinking agent

NIOSH PROFILE (ALDEHYDES), SRC, 4/78

NIOSH PROFILE (GLUTARALDEHYDE), SRC, 4/81

NIOSH PROFILE (ALDEHYDES), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Hormone
   Primary Irritant

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