FY 2003 Bench-to-Bedside Projects
| ICs |
Project/Investigator |
NIMH
NINDS |
"Investigation of Brain and Behavioral Effects of Specific Gene Deleted in 'Williams Syndrome Critical Area' of Chromosome 7q11.23 in Patients and Knockout Mice"
PIs: K. Berman, MD; J. Crawley, PhD
AI: A. Koretsky, PhD |
NHGRI
NINDS
|
"Sialic Acid Replacement in Patients with Hereditary Inclusion
Body Myopathy (HIBM) Caused by Mutations in the GNE (Sialuria) Gene"
PIs: M. Dalakas, MD; M. Juizing, PhD
AIs: D. Krasnewich, MD, PhD; O. Vasconcelos, MD
|
CC
NINDS
|
"MRI Detection of the Migration of Feridex -PPL Labeled
Cells into the CNS in Multiple Sclerosis Patients"
PI: J. Frank, MD; H. McFarland, MD
AIs: S. Ali, PhD; E. Jordan, DVM; B. Lewis; R. Martin, MD; B. Bielekova,
MD; N. Richert, MD, PhD; S. Anderson, PhD; J. Duyn, PhD; C. Carter; S. Leitman,
MD; E. Read, MD |
NCI
NHLBI
CC |
"Dendritic cell vaccination to augment graft-versus-leukemia
after allogeneic stem cell transplantation for acute lymphoblastic leukemia
(ALL)"
Clinical PI: A.Wayne,MD
Bench PI: C. Mackall, MD
AIs: A. J. Barrett, MD; M. Bishop, MD; C. Carter; T. Fry, MD; R.
Gress, MD; M. Grubbe, MD; R. Kurlander, MD; E. Read, MD |
NHLBI
NIAID |
"Evaluation of HMG-CoA reductase inhibitors in pulmonary
sarcoidosis"
Principal Translational: M. Park, MD, PhD
Principal Basic:V. Manganiello, MD, PhD
AI: J. Farber, MD |
NHLBI
NIAID
NHGRI |
"Clonal Insertion Site Analysis in Rhesus Macaques
& NIH Patients Transplanted with Retrovirally-Transduced Hematopoietic
Progenitor & Stem Cells: Implications for Leukemogenesis"
Basic PI: C. Dunbar, MD
Clinical PIs:F. Candotti, MD; H. Malech, MD
AIs: A. Baxevanis; R. Donahue |
FY 2003 AIDS Bench-to-Bedside Projects:
First Round
| ICs |
Project/Investigator |
NCI
NIAID
|
"Use of 5 Fluorouracil (5FU) in Combination with Antiretroviral
Drugs as a Salvage Strategy to Overcome Drug Resistance in Heavily Treated
HIV-Infected Pediatric Patients"
Bedside: L. Wood, MD
Bench: C. Womack, PhD |
Second Round
| ICs |
Project/Investigator |
NIAID
CC
|
"Imaging Probe for the In Vivo Assessment of HIV-1 Dynamics"
PI: M. DiMascio, PhD (NIAID)
AIs: S. Pandit, PhD (CCK);
. Li, MD, MBA (CC);
T. Imamichi, PhD (NIAID);
C. Lane, MD (NIAID)
|
NIDCR
CCMD, CC
|
"Therapeutic Targeting of a Virally Regulated Host Cell Molecule in HIV Infection"
PIs: Dr. S. M. Wahl (NIDCR);
Dr. H. Masur (CCMD)
AIs: Dr. MB Sporn (Dartmouth);
Dr. N. Vazquez (NIDCR)
|
NCI
NIAID
|
"Role of Recombination in HIV-1 Drug Resistance in vitro and in vivo"
F. Maldarelli (NCI); S. Palmer (NCI); W. Hu (NCI); J. Coffin (NCI);
M. Polis (NIAID); J. Mican (NIAID)
|
NCI
NIAID
|
"Treatment of Drug Resistant and Persistent HIV-1 Infection with the Designed Proteins 5-Helix and 5-Helix-PE"
PIs: Dr. Dean Hamer (NCI);
Dr. Joe Kovacs (NIAID)
|
CBER, FDA
VRC, NIH
|
"HIV-1 Infections During Vaccine Trials: Identifying New Peptides for the Differential Diagnosis of HIV-1 Infection in the Face of Vaccine-Generated Antibodies"
PI: Dr. Hana Golding, (CBER)
AI: Dr. Barney Graham, (VRC) |
NCI
NIAID
|
"Effect on Immune Responses and Sustainability of Viral Suppression in HIV-Infected Children of a Therapeutic Vaccination Strategy with a Multiclade HIV-1 DNA Plasmid Vaccine Prime and a Recombinant Adenovector Boost"
PIs: S. Zeichner, MD, PhD, HAMB, NCI (Bedside)
Richard Kroup, MD, VRC, NIAID (Bench) |
Awards Funded
2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999
This page last updated on 04/12/07
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