Research positions in transcription factor networks controlled by cytokine signaling
The Laboratory of Genetics and Physiology (LGP) at the National Institutes of Health in Bethesda explores cytokine signaling in normal physiology and disease. One focus is on mechanisms used by cytokines and transcription factors from the “Signal Transducer and Activator of Transcription” (STAT) family to control hematopoiesis and leukemia as well as mammary development and breast cancer. To address these questions we develop and use genetically altered mouse models as well as patient material. Over the past decade our laboratory has identified the importance of cytokine-STAT5 signaling in mammary development, liver physiology and different aspects of hematopoiesis.
We are currently recruiting two highly motivated and energetic scientists who wish to use and further develop modern mouse genetics in conjunction with emerging genomics technologies (such as ChIP-seq) and informatics to address key questions in physiology and cancer. One position will concentrate on the identification of cytokine-STAT-mediated signaling pathways in various hematopoietic lineages, leukemia and normal and neoplastic mammary tissue. The second position will use bioinformatics approaches to study cell specificity of cytokine-induced signaling networks. The initial appointment is for 2 years but can be extended.
For more information contact Lothar Hennighausen (lotharh@mail.nih.gov) and visit the LGP web site http://mammary.nih.gov/lgp
The National Institutes of Health are located in Bethesda just outside Washington, DC. The campus harbors hundreds of research groups and provides ample possibilities for collaborations. A joint program with the DFG allows German researchers to apply for funding for independent research groups upon return to Germany.