1. Kirk, KL Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules J. Fluorine Chem.(127): 1013-1029, 2006.
2. Tuan, E, Kirk, KL Fluorine reactivity in difluoromethylimidazoles J. Fluorine Chem.(127): 980-982, 2006.
3. Kirk, KL Selective flourinataion in drug design and development, an overview of biochemical rationales Current Topics Med. Chem.(6): 1447-1456, 2006.
4. Corpe CP, Lee JH, Kwon O, Eck P, Narayanan J, Kirk KL, Levine M 6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways. J Biol Chem (280): 5211-20, 2005. [Full Text/Abstract]
5. Eichler, JF, Cramer, JC, Kirk, KL, Bann, JG Biosynthesis of Chaperon Protein PapD Incorporating Fluorohistidine ChemBiochem(6): 2170-2173, 2005.
6. Ye S, Yoshida S, Frohlich R, Haufe G, Kirk KL Fluorinated phenylcyclopropylamines. Part 4: Effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines. Bioorg Med Chem (13): 2489-99, 2005. [Full Text/Abstract]
7. Rosen TC, Yoshida S, Kirk KL, Haufe G Fluorinated phenylcyclopropylamines as inhibitors of monoamine oxidases. Chembiochem (5): 1033-43, 2004. [Full Text/Abstract]
8. Yoshida S Meyer OG Rosen TC Haufe G Ye S Sloan MJ Kirk KL Fluorinated phenylcyclopropylamines. 1. Synthesis and effect of fluorine substitution at the cyclopropane ring on inhibition of microbial tyramine oxidase. J Med Chem (47): 1796-806, 2004. [Full Text/Abstract]
9. Rosen TC, Yoshida S, Frohlich R, Kirk KL, Haufe G Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase. J Med Chem (47): 5860-71, 2004. [Full Text/Abstract]
10. Yoshida S Rosen TC Meyer OG Sloan MJ Ye S Haufe G Kirk KL Fluorinated phenylcyclopropylamines. Part 3: Inhibition of monoamine oxidase A and B. Bioorg Med Chem (12): 2645-52, 2004. [Full Text/Abstract]
11. Ye S Rezende MM Deng WP Herbert B Daly JW Johnson RA Kirk KL Synthesis of 2'',5''-dideoxy-2-fluoroadenosine and 2'',5''-dideoxy-2,5''-difluoroadenosine: potent P-site inhibitors of adenylyl cyclase. J Med Chem (47): 1207-13, 2004. [Full Text/Abstract]
12. Deng WP Nam G Fan J Kirk KL Syntheses of beta,beta-difluorotryptamines. J Org Chem (68): 2798-802, 2003. [Full Text/Abstract]
13. Borri Voltattorni C Bertoldi M Bianconi S Deng WP Wong K Kim I Herbert B Kirk KL Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase. Biochem Biophys Res Commun (295): 107-11, 2002. [Full Text/Abstract]
14. Dolensky B Kirk KL New building blocks for fluorinated bioimidazole derivatives II: preparation of beta-fluorourocanic acids. J Org Chem (67): 3468-73, 2002. [Full Text/Abstract]
15. Dolensky B Kirk KL New building blocks for fluorinated imidazole derivatives: preparation of beta-fluoro- and beta,beta-difluorohistamine. J Org Chem (66): 4687-91, 2001. [Full Text/Abstract]
16. Herbert B Kim IH Kirk KL Synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-(3,4-dihydroxyphenyl)serine as potential in vivo precursors of fluorinated norepinephrines. J Org Chem (66): 4892-7, 2001. [Full Text/Abstract]
17. Ge P Kirk KL Synthesis of 2-Deoxy-2-halo-L-ascorbic Acids. J Org Chem (62): 3340-3343, 1997. [Full Text/Abstract]
18. Sloan MJ, Kirk KL Synthesis of a fluorinated analog of 1-aminocyclopropane carboxylic acid. Tetrahedron Letters (38): 1677-1689, 1997.
19. Creveling CR Padgett WL McNeal ET Cohen LA Kirk KL Incorporation of 2-fluorohistidine in murine protein in vivo. Life Sci (51): 1197-204, 1992. [Full Text/Abstract]
20. Eisenhofer G Hovevey-Sion D Kopin IJ Miletich R Kirk KL Finn R Goldstein DS Neuronal uptake and metabolism of 2- and 6-fluorodopamine: false neurotransmitters for positron emission tomographic imaging of sympathetically innervated tissues. J Pharmacol Exp Ther (248): 419-27, 1989. [Full Text/Abstract]