Testing Information

Testing Status of Agents at NTP

Asbestos, amosite

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http://ntp.niehs.nih.gov/go/TS-10761-X

CASRN: 12172-73-5

Synonyms/Common Names:

  • ASBESTOS, GRUNERITE

Known Uses:

ASBESTOS-CEMENT BUILDING PRODUCTS. FIRE-RESISTANT INSULATION PRODUCTS. (TDB)

Nomination Background

Short-Term Toxicity

  • 13-Week (Dosed-Feed)  (C60253A) Completed 
    • NTIS No. PB91-172312  (Peer Review 09/22/1982)
      Citation: Toxicology and Carcinogenesis Studies of Amosite Asbestos (CAS No. 12172-73-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N; Rats: F344/N

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C60253A) Report Complete 
    • TR-279 (NTIS No. PB91-172312)  (Peer Review 09/22/1982)
      Toxicology and Carcinogenesis Studies of Amosite Asbestos (CAS No. 12172-73-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N; Rats: F344/N
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
    • Dose: 0,1 %/250 PER GROUP
  • 2-Year (Dosed-Feed)  (C60253B) Report Complete 
    • TR-249 (NTIS No. PB87-133278)  (Peer Review 06/23/1981)
      Lifetime Carcinogenesis Studies of Amosite Asbestos (CAS No. 12172-73-5) in Syrian Golden Hamsters (Feed Studies)
    • Hamsters: Syrian Golden
    • Carcinogenesis Results
      • Male Hamsters Negative 
      • Female Hamsters Negative 
    • Dose: 0,1 %/250 PER GROUP

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Web page last updated on November 24, 2008