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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1686 IGR1681 IGR1682 IGR1683 IGR1685 IGR1688 IGR1687 IGR1689 pgsA, - SMu1951 SMu1950 SMu1952 trsA, - SMu1958 SMu1954 SMu1953 guaB,imdH, - SMu1957 SMu1955 recF, - SMu1956 pgsA, - SMu1951 SMu1950 SMu1952 trsA, - SMu1958 SMu1954 SMu1953 guaB,imdH, - SMu1957 SMu1955 recF, - SMu1956 pgsA, - SMu1951 SMu1950 SMu1952 trsA, - SMu1958 SMu1954 SMu1953 guaB,imdH, - SMu1957 SMu1949 SMu1949 SMu1955 recF, - SMu1956


LANL Gene ID: SMu1954

GenBank Locus Tag: SMU.2154c

DNA Molecule Name:
1  

GenBank ID:
24380482

Gene Name:


Definition:
peptidase, M16 family

Cellular Location:
Cytoplasm, Extracellular [Evidence]

Gene Start:
2016949

Gene Stop:
2015702

Gene Length:
1248

Molecular Weight*:
48732

pI*:
6.80

Net Charge*:
-1.22

EC:
 

Functional Class:
Unassigned  

Gene Ontology:

Pathway: pathway table

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several matches in gapped BLAST to conserved hypothetical proteins and proteases. Residues 1-414 are 52% similar to conserved hypothetical protein of Streptococcus pyogenes (gi15675932). Residues 9-414 are 38% similar to protease of Lactococcus lactis (gi15673955).







The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG2154 (1e-125).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380482|ref|NP_722437.1|  putative peptidase [Streptococ...   756   0.0  
 gi|50915213|ref|YP_061185.1|  Zinc protease [Streptococcus p...   438   e-121
 gi|94995362|ref|YP_603460.1|  Peptidase, M16 family [Strepto...   437   e-121
 gi|71904544|ref|YP_281347.1|  metalloprotease [Streptococcus...   436   e-120
 gi|71911663|ref|YP_283213.1|  zinc protease [Streptococcus p...   436   e-120
 gi|56808659|ref|ZP_00366383.1|  COG0612: Predicted Zn-depend...   436   e-120
 gi|19747031|ref|NP_608167.1|  hypothetical protein spyM18_22...   435   e-120
 gi|15675932|ref|NP_270106.1|  hypothetical protein SPy_2199 ...   435   e-120
 gi|139474619|ref|YP_001129335.1|  hypothetical protein SpyM5...   434   e-120
 gi|94993378|ref|YP_601477.1|  Peptidase, M16 family [Strepto...   434   e-120


InterPro Summary:  InterProScan

InterPro
IPR007863
Domain
Peptidase M16, C-terminal
PF05193 [187-351]T 6.19998763506012E-26 PF05193 Peptidase_M16_C Peptidase_M16_C
noIPR
unintegrated
unintegrated
G3DSA:3.30.830.10 [237-405]T 1.3999989204988999E-31 G3DSA:3.30.830.10 G3DSA:3.30.830.10 G3DSA:3.30.830.10
PTHR11851 [40-402]T 4.0999959904575E-31 PTHR11851 PTHR11851 PTHR11851
PTHR11851:SF61 [40-402]T 4.0999959904575E-31 PTHR11851:SF61 PTHR11851:SF61 PTHR11851:SF61
SSF63411 [2-217]T 4.999999999999999E-16 SSF63411 SSF63411[241-402]T 3.4999999999999996E-30 SSF63411 SSF63411 SSF63411


COGS Summary:  COGS Search
BeTs to 7 clades of COG0612
COG name: Predicted Zn-dependent peptidases
Functional Class: R
The phylogenetic pattern of COG0612 is ----YQvCEBrhUJ--o---x
Number of proteins in this genome belonging to this COG is 2
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 30-124 are 60% similar to a (PROTEOME COMPLETE PROTEASE BH2393) protein domain (PD072040 which is seen in O87529_STRPY.

Residues 255-414 are 50% similar to a (PROTEASE PROTEOME COMPLETE PROCESSING ZINC MITOCHONDRIAL) protein domain (PD001445 which is seen in O87529_STRPY.

Residues 132-231 are 55% similar to a (PROTEOME COMPLETE PROTEASE) protein domain (PD209861 which is seen in O87529_STRPY.

Residues 1-29 are 79% similar to a (DOMAIN OF UNKNO N) protein domain (PD173496 which is seen in O87529_STRPY.


Paralogs:  Local Blast Search
SMu1954 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search
Residues 186 to 351 (E-value = 1.8e-27) place SMu1954 in the Peptidase_M16_C family which is described as Peptidase M16 inactive domain (PF05193)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MKLAQDVQLHLLKTSQFKTNHITFRFSGELDSKTLARRVLVAQMLATANN
VYPTSQTFREKLANLYGAQFSTCISKKGKVHIVDIDISFVSDKFILEGKS
ILGEIIHFLRAALFKPLISVEHYQSKSFDLEKENLMRYLQSDKEDSFYYS
HLELQKLFFKDEVLKYSKYATAELVSAENSYTTYQEFQKMLKEDQIDIFV
LGDFDEYQVLQSIEEFPLEDRQKTLIFDYQQEYSKIVQEKVEQQENQQSL
LQLGYHFPIAYGDHNYYALLVFNGLLGVFPHSKLFTEVREKRRLAYNIGS
YFDIYTGLLQVYTGLDSNKRQQVFQLITKQFNDLKLGRFSSHLLAQTKKM
LINNMQLFEDNPKNRIEMHYNHCVFGDKCLELKEWIDRIDKVSKDDIVKA
ANLIKLQSIYFLEGE

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAATTAGCCCAAGATGTGCAGTTACACTTGCTTAAAACAAGTCAATT
TAAGACGAATCACATTACCTTTCGTTTTTCTGGTGAATTAGATAGTAAAA
CACTTGCTCGTCGTGTTTTAGTTGCTCAGATGTTGGCAACTGCTAATAAT
GTTTATCCAACATCTCAAACTTTTAGAGAAAAGTTGGCCAATTTATATGG
TGCTCAGTTTTCGACCTGTATATCAAAAAAAGGAAAGGTTCATATTGTTG
ATATAGACATTTCTTTTGTATCTGATAAATTTATTTTGGAAGGAAAGTCA
ATCTTAGGAGAAATTATCCATTTCTTAAGAGCGGCACTTTTTAAACCTCT
CATTTCAGTAGAGCATTATCAAAGTAAAAGTTTTGATCTTGAAAAAGAAA
ATTTAATGAGATATTTACAATCTGACAAAGAGGATTCTTTTTATTATAGT
CACTTAGAGTTACAAAAACTCTTTTTTAAAGATGAAGTTCTAAAATATTC
AAAATATGCTACTGCAGAGTTAGTAAGTGCTGAAAATTCCTATACAACGT
ACCAAGAATTTCAAAAAATGTTAAAAGAAGATCAGATTGATATCTTTGTT
TTGGGGGATTTCGATGAATATCAAGTTTTACAATCTATTGAAGAATTTCC
CTTAGAAGATCGCCAAAAAACATTGATCTTTGATTACCAACAAGAATATT
CGAAGATTGTTCAGGAAAAAGTTGAACAGCAAGAAAACCAACAGTCTCTT
TTACAACTAGGCTATCATTTTCCTATAGCTTATGGAGATCATAATTACTA
TGCCCTACTTGTTTTTAATGGTCTTTTAGGAGTTTTTCCTCATTCTAAAT
TATTTACTGAAGTTCGAGAAAAAAGAAGATTGGCTTATAATATTGGAAGT
TATTTTGATATTTACACAGGTTTACTTCAAGTTTACACAGGTCTTGACAG
TAACAAAAGACAACAGGTATTTCAGTTGATAACAAAGCAATTCAATGATT
TAAAATTAGGCCGGTTTTCAAGCCATTTATTAGCTCAAACAAAAAAGATG
TTAATAAACAATATGCAATTATTTGAGGACAACCCCAAAAATAGAATTGA
AATGCATTATAATCATTGTGTTTTTGGAGATAAATGTTTAGAGCTGAAAG
AATGGATTGACAGAATTGACAAAGTTAGTAAAGACGATATTGTCAAAGCA
GCTAATCTCATTAAGTTACAGTCTATTTATTTTTTAGAAGGAGAGTAG

Los Alamos National Laboratory • Est 1943

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