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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1534 IGR1531 IGR1539 IGR1529 IGR1530 IGR1535 IGR1533 IGR1538 groES, - SMu1775 SMu1776 SMu1786 ssbA, - SMu1785 SMu1787 levD,ptfA, - SMu1780 levE, - SMu1779 levG,ptnD, - SMu1777 levF, - SMu1778 rbsB, - SMu1784 levQ, - SMu1781 levS, - SMu1783 groEL, - SMu1774 groES, - SMu1775 SMu1776 SMu1786 ssbA, - SMu1785 SMu1787 levD,ptfA, - SMu1780 levE, - SMu1779 levG,ptnD, - SMu1777 levF, - SMu1778 rbsB, - SMu1784 levQ, - SMu1781 levS, - SMu1783 groEL, - SMu1774 SMu1776 SMu1787 levD,ptfA, - SMu1780 levE, - SMu1779 levG,ptnD, - SMu1777 levF, - SMu1778 rbsB, - SMu1784 levQ, - SMu1781 levS, - SMu1783 groEL, - SMu1774 levR, - SMu1782 levR, - SMu1782 groES, - SMu1775 ssbA, - SMu1785 SMu1786


LANL Gene ID: SMu1781

GenBank Locus Tag: SMU.1963c

DNA Molecule Name:
1  

GenBank ID:
24380307

Gene Name:
levQ  

Definition:
sugar-binding periplasmic protein

Cellular Location:
Extracellular, Membrane [Evidence]

Gene Start:
1840289

Gene Stop:
1838982

Gene Length:
1308

Molecular Weight*:
49601

pI*:
9.80

Net Charge*:
11.79

EC:
 

Functional Class:
Transport and binding proteins; ABC Superfamily: substrate-binding protein  

Gene Ontology:
Biological process
  GO:0006810    transport

Molecular function
  GO:0005215    transporter activity


Pathway: pathway table

Primary Evidence:
Zeng L, Wen ZT, Burne RA,
A novel signal transduction system and feedback loop regulate fructan hydrolase gene expression in Streptococcus mutans.
Mol Microbiol. 2006 Oct;62(1):187-200.
PMID: 16987177

Comment:



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
One very strong and several weak significant hits in gapped BLAST to sugar-binding periplasmic proteins; residues 32-434 are 46% similar to sugar-binding periplasmic protein of Clostridium acetobutylicum (15894735); residues 54-245 are 31% similar to sugar ABC transporter, sugar-binding of Listeria monocytogenes (16802227).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0034 (4e-08).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380307|ref|NP_722262.1|  putative sugar-binding peripla...   790   0.0  
 gi|157075619|gb|ABV10302.1|  sugar-binding cell envelope pro...   451   e-125
 gi|125717096|ref|YP_001034229.1|  Sugar-binding periplasmic ...   447   e-124
 gi|90961070|ref|YP_534986.1|  Putative sugar-binding protein...   412   e-113
 gi|15894735|ref|NP_348084.1|  Sugar-binding periplasmic prot...   365   3e-99
 gi|153852993|ref|ZP_01994430.1|  hypothetical protein DORLON...   312   4e-83
 gi|42519537|ref|NP_965467.1|  hypothetical protein LJ1660 [L...   269   3e-70
 gi|146296569|ref|YP_001180340.1|  extracellular solute-bindi...    84   2e-14
 gi|16264844|ref|NP_437636.1|  putative sugar uptake ABC tran...    82   7e-14
 gi|153198400|ref|ZP_01942450.1|  sugar ABC transporter, suga...    81   1e-13


InterPro Summary:  InterProScan

InterPro
IPR006059
Family
Bacterial extracellular solute-binding protein, family 1
PF01547 [15-342]T 3.50000235434301E-11 PF01547 SBP_bac_1 SBP_bac_1
noIPR
unintegrated
unintegrated
G3DSA:3.40.190.10 [47-363]T 6.500008052301379E-25 G3DSA:3.40.190.10 G3DSA:3.40.190.10 G3DSA:3.40.190.10
SSF53850 [47-435]T 5.699999999999999E-56 SSF53850 SSF53850 SSF53850


COGS Summary:  COGS Search
BeTs to 5 clades of COG1653
COG name: Sugar-binding periplasmic proteins/domains
Functional Class: G
The phylogenetic pattern of COG1653 is ---K--VCEBR------l---
Number of proteins in this genome belonging to this COG is 2
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 50-177 are 25% similar to a (COMPLETE PROTEOME SUGAR TRANSPORT) protein domain (PD001485 which is seen in YURO_BACSU.


Paralogs:  Local Blast Search
SMu1781 is paralogously related (blast p-value < 1e-3) to SMu1425, a predicted maltose/maltodextrin-binding protein.


Pfam Summary:  Pfam Search
Residues 15 to 342 (E-value = 1.3e-13) place SMu1781 in the SBP_bac_1 family which is described as Bacterial extracellular solute-binding protein (PF01547)

 Structural Feature(s):
Feature Type  Start  Stop
cleavable  
1  
31

Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MIKKRLYQYKFHLLVLLVLLGALLTLFLVQSRQKKILRLGVYAGSSWDVP
SGKDYQFLDSVIKRFEKAHPNVDVQYETGILKEDYSSWLSKKIVEGKQPD
VFMVPENDFNLLASTKTLANLDSYIKKDLKPSLFYHSAYNSGQFERKQFA
LPFESNPVMMCINNDLLKKEGIELPNSSWTLNDFYSICKKVTKDTDGDGV
IDQYGSLGYGWEEALAAYNVKLFNETGTEAYFNTKRVRSALALVTKLKSL
NGNYNVTLKDFDEGKVAFYPMTLAQYRTYKPYPYHVAKYSSFSWSCVEMP
SQKPNTAKIQINTSLYAMSSKTSQSKLAWEFLKLLCANKKSQQQLFEESQ
GASVLKSVMNSQASKNLLQNDSFGSKALTVNTLDNMMRKAKTTPKFKSYN
TIYEKAGYLITKSLEGNTVENDLSDIQKEIEEELK

Gene Nucleotide Sequence:  Sequence Viewer
ATGATTAAAAAACGGCTTTACCAGTATAAATTTCACCTATTGGTCTTGTT
GGTACTTTTAGGAGCCCTGTTAACCTTATTTCTTGTGCAATCGCGGCAAA
AGAAAATCTTGAGATTAGGTGTTTATGCTGGCAGTAGCTGGGATGTACCC
AGTGGGAAAGATTATCAATTTTTAGATAGTGTCATTAAACGGTTTGAAAA
GGCTCATCCAAATGTTGATGTTCAATATGAGACTGGCATTTTAAAAGAAG
ATTATTCTTCGTGGCTGTCTAAAAAAATTGTTGAGGGAAAGCAACCAGAT
GTTTTTATGGTTCCTGAAAATGATTTTAATCTTTTAGCTTCAACAAAAAC
TTTAGCTAATTTAGATAGTTATATTAAAAAAGATTTGAAACCTTCGCTCT
TTTATCATTCAGCCTATAATTCAGGTCAATTTGAAAGGAAACAATTTGCC
CTTCCCTTTGAAAGCAATCCTGTTATGATGTGCATCAATAATGATCTCTT
AAAAAAAGAGGGAATAGAGTTACCAAACTCTTCATGGACCTTAAACGATT
TTTATAGTATTTGTAAAAAAGTTACCAAGGATACAGATGGTGATGGTGTT
ATTGATCAATATGGCAGTCTAGGTTATGGTTGGGAAGAGGCTTTAGCTGC
CTATAATGTTAAGTTATTTAATGAAACTGGTACAGAGGCTTACTTTAACA
CCAAAAGAGTTCGTTCGGCTTTAGCATTAGTCACAAAATTAAAGAGCTTA
AATGGTAATTATAATGTTACTCTTAAAGATTTTGATGAGGGTAAGGTTGC
TTTTTATCCTATGACTCTAGCTCAATATCGTACTTATAAACCCTATCCTT
ATCATGTTGCAAAATACTCTTCCTTTTCGTGGTCTTGTGTTGAAATGCCT
TCACAAAAACCAAATACGGCGAAGATACAAATTAATACATCTTTATATGC
TATGTCGTCCAAAACTTCACAGTCTAAATTAGCTTGGGAGTTTCTTAAAC
TTTTATGTGCCAATAAAAAATCACAACAGCAATTATTTGAAGAATCACAA
GGAGCATCTGTTTTAAAATCAGTAATGAACAGTCAAGCAAGTAAGAATCT
TTTGCAAAATGATAGCTTTGGTTCAAAAGCTTTGACTGTTAATACCTTGG
ACAATATGATGCGAAAAGCGAAAACGACTCCTAAATTTAAATCTTATAAT
ACTATTTATGAAAAAGCAGGCTATCTTATTACCAAATCGTTGGAAGGAAA
TACTGTAGAAAATGATTTATCTGATATTCAAAAAGAAATTGAAGAAGAAT
TAAAGTAG

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