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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1436 IGR1435 IGR1433 IGR1431 IGR1437 IGR1438 IGR1432 IGR1429 IGR1434 pncA, - SMu1661 codY, - SMu1662 alr, - SMu1670 yfbQ, - SMu1663 SMu1666 recG, - SMu1669 SMu1668 uspA, - SMu1665 yhfU,bioB, - SMu1664 aspG,ansB, - SMu1667 pncA, - SMu1661 codY, - SMu1662 alr, - SMu1670 yfbQ, - SMu1663 SMu1666 recG, - SMu1669 SMu1668 uspA, - SMu1665 yhfU,bioB, - SMu1664 aspG,ansB, - SMu1667 pncA, - SMu1661 codY, - SMu1662 alr, - SMu1670 yfbQ, - SMu1663 SMu1666 recG, - SMu1669 SMu1668 uspA, - SMu1665 yhfU,bioB, - SMu1664 aspG,ansB, - SMu1667


LANL Gene ID: SMu1666

GenBank Locus Tag: SMU.1830c

DNA Molecule Name:
1  

GenBank ID:
24380192

Gene Name:


Definition:
conserved hypothetical protein

Cellular Location:
Cytoplasm, Membrane [Evidence]

Gene Start:
1726944

Gene Stop:
1725544

Gene Length:
1401

Molecular Weight*:
52316

pI*:
9.00

Net Charge*:
5.83

EC:
 

Functional Class:
Unknown  

Gene Ontology:
Biological process
  GO:0008152    metabolic process

Molecular function
  GO:0003824    catalytic activity
  GO:0016787    hydrolase activity


Pathway: pathway table

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to conserved hypothetical proteins. Residues 6-463 are 67% similar to 15675621 from S.pyogenes. Residues 8-466 are 54% similar to >15901820 from S.pneumoniae, a predicted Cof family protein.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1678 (0.0).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380192|ref|NP_722147.1|  hypothetical protein SMU.1830c...   941   0.0  
 gi|116628409|ref|YP_821028.1|  hypothetical protein STER_168...   664   0.0  
 gi|77409001|ref|ZP_00785721.1|  hydrolase, haloacid dehaloge...   664   0.0  
 gi|55821695|ref|YP_140137.1|  conserved hypothetical protein...   663   0.0  
 gi|22537818|ref|NP_688669.1|  hydrolase, haloacid dehalogena...   662   0.0  
 gi|25011762|ref|NP_736157.1|  hypothetical protein gbs1722 [...   659   0.0  
 gi|94991092|ref|YP_599192.1|  Hydrolase [Streptococcus pyoge...   643   0.0  
 gi|21911083|ref|NP_665351.1|  hypothetical protein SpyM3_154...   642   0.0  
 gi|15675621|ref|NP_269795.1|  hypothetical protein SPy_1781 ...   642   0.0  
 gi|139473207|ref|YP_001127922.1|  haloacid dehalogenase-like...   642   0.0


InterPro Summary:  InterProScan

InterPro
IPR000150
Family
Cof protein
TIGR00099 [10-278]T 8.350988691290912E-55 TIGR00099 Cof-subfamily Cof-subfamily
PS01228 [10-21]? 0.0 PS01228 COF_1 COF_1
PS01229 [232-254]T 8.0E-5 PS01229 COF_2 COF_2
InterPro
IPR006379
Family
HAD-superfamily hydrolase, subfamily IIB
TIGR01484 [10-251]T 5.02345274065118E-17 TIGR01484 HAD-SF-IIB HAD-SF-IIB
InterPro
IPR013200
Domain
HAD superfamily hydrolase-like, type 3
PF08282 [11-278]T 1.59998835313659E-90 PF08282 Hydrolase_3 Hydrolase_3
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.1000 [4-281]T 1.4999964819631798E-45 G3DSA:3.40.50.1000 G3DSA:3.40.50.1000 G3DSA:3.40.50.1000
SSF56784 [1-287]T 1.2999999999999999E-58 SSF56784 SSF56784 SSF56784


COGS Summary:  COGS Search
BeTs to 12 clades of COG0561
COG name: Predicted hydrolases of the HAD superfamily
Functional Class: R
The phylogenetic pattern of COG0561 is a-tky-vCEBrH--GPOlin-
Number of proteins in this genome belonging to this COG is 11
Blocks Summary:  Blocks Search
***** IPB000150 (Cof protein) with a combined E-value of 2.4e-30.
    IPB000150A    7-21
    IPB000150B    41-50
    IPB000150C    230-262


 ProDom Summary:  Protein Domain Search
Residues 8-197 are 24% similar to a (PROTEOME COMPLETE YCEE Y) protein domain (PD415810 which is seen in Q9CIW2_LACLA.

Residues 382-457 are 71% similar to a (PROTEOME COMPLETE YHED) protein domain (PD351823 which is seen in Q9CHJ4_LACLA.

Residues 264-381 are 54% similar to a (PROTEOME COMPLETE YHED) protein domain (PD396035 which is seen in Q9CHJ4_LACLA.

Residues 19-107 are 49% similar to a (PROTEOME COMPLETE YJBC YRAE) protein domain (PD095670 which is seen in Q9CHJ4_LACLA.

Residues 108-215 are 37% similar to a (PROTEOME COMPLETE YHED) protein domain (PD394915 which is seen in Q9CHJ4_LACLA.

Residues 209-264 are 51% similar to a (PROTEOME COMPLETE HYDROLASE ATPASE) protein domain (PD001342 which is seen in Q9CKQ1_PASMU.


Paralogs:  Local Blast Search
SMu1666 is paralogously related (blast p-value < 1e-3) to SMu0461, SMu0388, SMu0655, SMu0442, SMu0675, SMu1012, SMu0674, and SMu0367, all conserved hypotheticals.


Pfam Summary:  Pfam Search
Residues 8 to 255 (E-value = 4.7e-08) place SMu1666 in the Hydrolase family which is described as haloacid dehalogenase-like hydrolase (PF00702)

 Structural Feature(s):
Feature Type  Start  Stop
transmembrane  
386  
402

Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MKGNIVAIKAVFFDIDGTLLNDRKQVQKSTQDAIANMKKQGIFVGVATGR
GPAFVAPFMENLGLDFAITYNGQYIFTRDRILYQNQLPKSTVYRLIKYAS
EQRREISLGTSSGLVGSNIINMGTSRFGQWISRMVPKRWTKTITRSFKHV
VRRVKPQSLNSLMTIMRQPIFQIVLVATKEQSDIIAKKFPHLTITRSSLY
SADLISKGMSKIKGVLCVAREFDIEIEEVMAFGDSDNDLEMLSGVGISVA
MGNATEQVKTIADYTTASNNNDGISQALAHFGVIHQKTDRVFSSSDDNFN
KVKDFHQLMDGETCEIPRIYDIVEGGHRSAFKAEEIVEFLYATSNGDKEE
FAQALARLHKAVDKAAEKVLSKPHPETPLVGQVDALIDLLYLTYGSFVLM
GVDPKPFFDTVHEANIGKIFPDGKAHFDPETHKILKPDDWEERFAPEPAI
KRELDRQIQKSLQHRK

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAAGGTAATATTGTGGCAATCAAGGCTGTCTTTTTTGATATTGATGG
GACGCTTTTAAATGATCGAAAACAGGTTCAGAAATCGACACAAGATGCAA
TTGCAAATATGAAAAAACAAGGCATCTTCGTTGGTGTAGCAACTGGTCGG
GGTCCGGCTTTTGTTGCGCCTTTTATGGAAAATTTAGGGCTTGATTTTGC
TATCACCTATAATGGTCAATATATTTTCACGCGCGATCGTATTTTATACC
AAAATCAGTTACCCAAATCAACAGTTTATCGTCTTATTAAATACGCCAGT
GAACAAAGGCGAGAAATTTCTCTGGGAACGAGTTCTGGTCTTGTTGGTTC
TAATATCATTAACATGGGAACCAGTCGTTTTGGTCAATGGATCAGTCGTA
TGGTTCCCAAAAGGTGGACTAAAACGATTACTCGTAGTTTTAAACATGTA
GTTCGTCGTGTTAAACCACAGAGCTTAAATAGTTTGATGACCATTATGCG
CCAGCCTATCTTTCAAATTGTTTTGGTGGCAACTAAGGAACAAAGTGACA
TTATTGCTAAAAAATTCCCCCATTTGACCATTACTCGCAGTAGCCTGTAC
TCTGCTGATTTAATTTCTAAAGGCATGTCCAAAATAAAGGGTGTTTTATG
TGTTGCCAGAGAATTTGATATTGAAATAGAAGAAGTCATGGCTTTTGGTG
ATTCTGATAACGATCTTGAAATGTTATCAGGAGTTGGGATAAGTGTTGCT
ATGGGCAATGCTACTGAACAAGTCAAAACGATTGCGGACTATACAACTGC
TAGCAATAATAATGATGGTATTTCTCAGGCTCTAGCACATTTTGGTGTTA
TCCATCAAAAAACAGATAGAGTCTTTTCAAGTAGTGATGACAATTTTAAT
AAAGTCAAAGATTTTCATCAACTAATGGATGGCGAAACCTGTGAAATACC
TAGAATTTACGACATTGTTGAAGGTGGGCACCGTTCAGCTTTTAAAGCTG
AAGAAATTGTTGAATTCTTATATGCTACAAGTAACGGTGATAAGGAAGAA
TTTGCTCAAGCACTTGCTAGACTTCATAAAGCGGTTGATAAGGCTGCAGA
GAAAGTTTTGTCAAAGCCGCATCCAGAAACGCCTTTAGTTGGACAAGTAG
ATGCTTTGATTGATTTATTGTATCTCACTTATGGTTCCTTTGTATTAATG
GGAGTAGACCCTAAACCCTTTTTTGATACAGTACATGAAGCTAATATTGG
AAAGATCTTTCCAGATGGTAAGGCCCATTTTGATCCAGAAACACATAAAA
TTTTAAAGCCTGATGACTGGGAAGAGCGCTTTGCACCTGAACCAGCCATC
AAAAGAGAATTGGATCGTCAAATCCAGAAATCCTTACAGCATCGTAAATG
A

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