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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1349 IGR1351 IGR1350 IGR1356 IGR1346 IGR1352 IGR1354 IGR1355 IGR1348 IGR1347 IGR1353 SMu1567 greA, - SMu1574 SMu1576 SMu1570 SMu1569 cspR, - SMu1571 murI, - SMu1566 lysA,tabA, - SMu1568 murC, - SMu1577 pabC, - SMu1575 SMu1572 SMu1573 SMu1567 greA, - SMu1574 SMu1576 SMu1570 SMu1569 cspR, - SMu1571 murI, - SMu1566 lysA,tabA, - SMu1568 murC, - SMu1577 pabC, - SMu1575 SMu1572 SMu1573 greA, - SMu1574 SMu1576 SMu1569 cspR, - SMu1571 murI, - SMu1566 lysA,tabA, - SMu1568 murC, - SMu1577 pabC, - SMu1575 SMu1567 SMu1570 SMu1572 SMu1573


LANL Gene ID: SMu1573

GenBank Locus Tag: SMU.1727

DNA Molecule Name:
1  

GenBank ID:
24380099

Gene Name:


Definition:
OxaA-like protein; inner membrane protein

Cellular Location:
Membrane, Periplasm, Extracellular [Evidence]

Gene Start:
1631478

Gene Stop:
1632410

Gene Length:
933

Molecular Weight*:
34864

pI*:
11.10

Net Charge*:
28.85

EC:
 

Functional Class:
Cell envelope; Other  

Gene Ontology:
Biological process
  GO:0051205    protein insertion into membrane

Cellular component
  GO:0016020    membrane
  GO:0016021    integral to membrane


Pathway: pathway table

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Significant hits in gapped BLAST to hypothetical proteins. Residues 1-306 are 505 similar to >gi15674505 as seen in S. pyogenes. Residues 3-306 are 43% similar to >gi15903832 as seen in S. pneumoniae.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1608 (2e-83).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380099|ref|NP_722054.1|  OxaA-like protein precursor [S...   563   e-159
 gi|55822232|ref|YP_140673.1|  OxaA-like protein precursor [S...   336   1e-90
 gi|55820342|ref|YP_138784.1|  OxaA-like protein precursor [S...   336   1e-90
 gi|21909792|ref|NP_664060.1|  OxaA-like protein precursor [S...   329   2e-88
 gi|71902952|ref|YP_279755.1|  OxaA-like protein precursor [S...   328   2e-88
 gi|15674505|ref|NP_268679.1|  OxaA-like protein precursor [S...   327   8e-88
 gi|139474368|ref|YP_001129084.1|  membrane protein OxaA 2 pr...   326   1e-87
 gi|94993686|ref|YP_601784.1|  60 kDa inner membrane protein ...   325   2e-87
 gi|19745513|ref|NP_606649.1|  OxaA-like protein precursor [S...   325   2e-87
 gi|94989800|ref|YP_597900.1|  60 kDa inner membrane protein ...   325   3e-87


InterPro Summary:  InterProScan

InterPro
IPR001708
Family
60 kDa inner membrane insertion protein
PR00701 [133-156]T 3e-07 PR00701 60KDINNERMP[216-239]T 3e-07 PR00701 60KDINNERMP 60KDINNERMP
PTHR12428 [40-257]T 8.3e-43 PTHR12428 OXA1 OXA1
PF02096 [61-253]T 8.7e-38 PF02096 60KD_IMP 60KD_IMP
InterPro
IPR006741
Family
Accessory gene regulator B
SM00793 [95-258]T 1.9e+02 SM00793 no description no description
noIPR
unintegrated
unintegrated
PTHR12428:SF11 [40-257]T 8.3e-43 PTHR12428:SF11 OXAA 1, 2 OXAA 1, 2
signalp [1-30]? NA signalp signal-peptide signal-peptide
tmhmm [9-27]? NA tmhmm transmembrane_regions[57-77]? NA tmhmm transmembrane_regions[136-156]? NA tmhmm transmembrane_regions[175-195]? NA tmhmm transmembrane_regions[216-236]? NA tmhmm transmembrane_regions transmembrane_regions


COGS Summary:  COGS Search
BeTs to 11 clades of COG0706
COG name: Inner membrane proteins, SpoIIIJ family
Functional Class: S
The phylogenetic pattern of COG0706 is ----yqvceBrhujgpolinx
Number of proteins in this genome belonging to this COG is 2
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 78-252 are 25% similar to a (TRANSMEMBRANE PROTEOME COMPLETE) protein domain (PD409339 which is seen in O66561_AQUAE.

Residues 78-247 are 50% similar to a (MEMBRANE COMPLETE PROTEOME INNER) protein domain (PD002157 which is seen in Q9CHZ9_LACLA.


Paralogs:  Local Blast Search
SMu1573 is paralogously related (blast p-value < 1e-3) to SMu0303, a possible inner membrane protein.


Pfam Summary:  Pfam Search
Residues 61 to 253 (E-value = 1.4e-38) place SMu1573 in the 60KD_IMP family which is described as 60Kd inner membrane protein (PF02096)

 Structural Feature(s):
Feature Type  Start  Stop
may be a lipoprotein  
  
transmembrane  
61  
77
transmembrane  
138  
154
transmembrane  
179  
195
transmembrane  
211  
227

Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MKKIYKRLLFSGLALSMLFFLSGCVQMKNGKPTGEGWVYKFFAAPMGSVI
QYLANNLGLGFGFAIIIVTVIVRLLILPLGLSQVRKMTYQSEKMAYLKPV
FDPIQERMKNAKTQEEKMAAQTELMQAQRHYGMSMFGGLGCLPLLIQMPF
FSALYISTRYTKGIASASFLGIKLGSPNMIITVIIGILYLVQSWVSTLSV
PEAQRQQTRNMMFMMPIMMVMISIGAPAGGALYWLVSGIFGLIQQLITNH
IIKPKLRKQIDEEFKKNPPKPFKSNARKDITPQANNDKKLITSKKQKSNR
NAGKQRHHKQ

Gene Nucleotide Sequence:  Sequence Viewer
GTGAAAAAAATTTACAAGCGTCTTTTATTTTCGGGCTTAGCTCTGTCTAT
GCTTTTTTTCCTATCTGGTTGCGTGCAGATGAAAAATGGAAAACCAACTG
GTGAAGGTTGGGTTTACAAATTTTTTGCTGCCCCAATGGGAAGTGTTATC
CAATATTTAGCTAATAATCTTGGTCTGGGATTTGGCTTTGCTATTATCAT
TGTCACAGTTATTGTCCGTCTTCTCATCTTGCCATTAGGTCTTAGTCAAG
TACGAAAGATGACTTACCAATCTGAGAAAATGGCTTATCTAAAACCAGTC
TTTGATCCTATTCAAGAACGCATGAAGAATGCCAAAACTCAGGAAGAAAA
AATGGCTGCTCAAACAGAATTAATGCAGGCGCAGCGTCATTACGGTATGA
GCATGTTTGGTGGTTTAGGATGTCTACCGCTGCTGATCCAGATGCCTTTC
TTCTCTGCACTTTATATTTCTACCCGTTACACCAAGGGAATCGCCAGTGC
TAGTTTCTTAGGTATTAAACTTGGCAGTCCAAATATGATCATCACTGTTA
TTATTGGAATTCTTTATCTTGTTCAGTCTTGGGTTTCAACGCTAAGTGTT
CCAGAAGCACAAAGACAGCAAACAAGAAATATGATGTTTATGATGCCAAT
TATGATGGTTATGATTTCCATAGGTGCTCCTGCTGGAGGTGCTCTTTACT
GGCTAGTCAGTGGTATTTTTGGTCTCATCCAACAATTGATCACAAACCAT
ATCATTAAACCAAAATTGCGGAAGCAAATTGATGAAGAATTTAAGAAAAA
CCCTCCAAAACCTTTCAAATCAAATGCTCGTAAAGATATCACTCCACAAG
CCAATAATGATAAAAAGCTTATAACCTCTAAAAAGCAAAAGTCCAACCGC
AATGCAGGTAAACAGCGTCACCATAAGCAATAA

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