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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1136 IGR1135 IGR1132 IGR1129 IGR1134 IGR1133 IGR1131 SMu1309 SMu1310 bgc, - SMu1307 SMu1302 yvyH, - SMu1311 icaA, - SMu1308 SMu1306 cobQ, - SMu1305 murC, - SMu1304 SMu1309 SMu1310 bgc, - SMu1307 SMu1302 yvyH, - SMu1311 icaA, - SMu1308 SMu1306 cobQ, - SMu1305 murC, - SMu1304 SMu1310 bgc, - SMu1307 SMu1302 yvyH, - SMu1311 icaA, - SMu1308 SMu1306 SMu1303 SMu1303 SMu1309 cobQ, - SMu1305 murC, - SMu1304


LANL Gene ID: SMu1306

GenBank Locus Tag: SMU.1431c

DNA Molecule Name:
1  

GenBank ID:
24379834

Gene Name:


Definition:
ABC transporter, ATP-binding protein

Cellular Location:
Cytoplasm, Membrane [Evidence]

Gene Start:
1365303

Gene Stop:
1363390

Gene Length:
1914

Molecular Weight*:
72227

pI*:
4.80

Net Charge*:
-24.49

EC:
 

Functional Class:
Transport and binding proteins; ABC Superfamily: ATP-binding protein  

Gene Ontology:
Molecular function
  GO:0000166    nucleotide binding
  GO:0005524    ATP binding
  GO:0016887    ATPase activity
  GO:0017111    nucleoside-triphosphatase activity


Pathway: pathway table

Comment:
This sequence contains two nucleotide binding domains.



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several hits in gapped BLAST to ABC ATP-binding proteins. Residues 1-612 are 76% similar to 15675024| from S.pyogenes and
residues 1-611 are 75% similar to 15900981| from S.pneumoniae.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0877 (0.0).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379834|ref|NP_721789.1|  putative ABC transporter, ATP-...  1154   0.0  
 gi|55821265|ref|YP_139707.1|  ABC transporter, drug resistan...   923   0.0  
 gi|116628002|ref|YP_820621.1|  ATPase component of ABC trans...   922   0.0  
 gi|146319130|ref|YP_001198842.1|  ATPase component of ABC tr...   909   0.0  
 gi|81096825|ref|ZP_00875154.1|  ABC transporter [Streptococc...   905   0.0  
 gi|94990377|ref|YP_598477.1|  ABC transporter ATP-binding pr...   901   0.0  
 gi|139473845|ref|YP_001128561.1|  ABC transporter ATP-bindin...   901   0.0  
 gi|94988495|ref|YP_596596.1|  ABC transporter ATP-binding pr...   901   0.0  
 gi|50914121|ref|YP_060093.1|  ABC transporter ATP-binding pr...   900   0.0  
 gi|19746009|ref|NP_607145.1|  putative ABC transporter (ATP-...   900   0.0


InterPro Summary:  InterProScan

InterPro
IPR003439
Domain
ABC transporter related
PD000006 [162-205]T 0.0 PD000006 ABC_transporter[444-486]T 0.0 PD000006 ABC_transporter ABC_transporter
PF00005 [31-235]T 2.9999875044572003E-41 PF00005 ABC_tran[354-517]T 1.9999963603453602E-33 PF00005 ABC_tran ABC_tran
PS00211 [444-458]? 0.0 PS00211 ABC_TRANSPORTER_1 ABC_TRANSPORTER_1
PS50893 [4-260]T 0.0 PS50893 ABC_TRANSPORTER_2[327-541]T 0.0 PS50893 ABC_TRANSPORTER_2 ABC_TRANSPORTER_2
InterPro
IPR003593
Domain
AAA+ ATPase, core
SM00382 [28-243]T 5.59999999999999E-10 SM00382 AAA[351-517]T 7.20000000000052E-12 SM00382 AAA AAA
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [2-282]T 1.0E-36 G3DSA:3.40.50.300 G3DSA:3.40.50.300[289-532]T 2.3000044072653901E-35 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR19211 [133-614]T 0.0 PTHR19211 PTHR19211 PTHR19211
PTHR19211:SF11 [133-614]T 0.0 PTHR19211:SF11 PTHR19211:SF11 PTHR19211:SF11
SSF52540 [6-246]T 9.3E-47 SSF52540 SSF52540[327-593]T 7.299999999999999E-45 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 10 clades of COG0488
COG name: ATPase components of ABC transporters with duplicated ATPase domains
Functional Class: R
The phylogenetic pattern of COG0488 is ----Y--CEBRHuj--olinx
Number of proteins in this genome belonging to this COG is 4
Blocks Summary:  Blocks Search
***** IPB001140 (ABC transporter transmembrane region) with a combined E-value of 5.3e-25.
    IPB001140A    18-64
    IPB001140B    160-198
    IPB001140A    341-387
    IPB001140B    441-479


 ProDom Summary:  Protein Domain Search
Residues 491-610 are 22% similar to a (ATP-BINDING SUBUNIT ABC TRANSPORT) protein domain (PD062423 which is seen in Q9K3R7_STRCO.

Residues 253-341 are 27% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD282180 which is seen in Q9KBA3_BACHD.

Residues 441-486 are 54% similar to a (PROTEOME BINDING ATP-BINDING COMPLETE) protein domain (PD335182 which is seen in Q9X7B1_MYCLE.

Residues 212-502 are 27% similar to a (ATP-BINDING ABC TRANSPORTER) protein domain (PD068705 which is seen in Q9ZC01_STRCO.

Residues 345-442 are 33% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD220985 which is seen in Q9KFD1_BACHD.

Residues 391-505 are 36% similar to a (ATP-BINDING) protein domain (PD397028 which is seen in Q53712_STRAT.

Residues 145-205 are 39% similar to a (ATP-BINDING RESISTANCE PLASMID COMPLETE) protein domain (PD019698 which is seen in Q9ZKZ3_HELPJ.

Residues 444-488 are 57% similar to a (PROTEOME COMPLETE ABC TRANSPORTER) protein domain (PD188894 which is seen in Q9Z9F8_CHLPN.

Residues 422-483 are 38% similar to a (ABC TRANSPORTER ABC-TRANSPORTER) protein domain (PD330281 which is seen in Q9F901_STRPN.

Residues 262-337 are 68% similar to a (ATP-BINDING PROTEOME TRANSPORTER COMPLETE) protein domain (PD331218 which is seen in Q9CGN4_LACLA.

Residues 251-336 are 31% similar to a (ATP-BINDING TRANSPORTER ABC PROTEOME) protein domain (PD004492 which is seen in YHES_ECOLI.

Residues 159-205 are 57% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD250554 which is seen in Q9KBA3_BACHD.

Residues 489-532 are 55% similar to a (ATP-BINDING ABC TRANSPORTER PROTEOME COMPLETE REPEAT) protein domain (PD000796 which is seen in Q9CGN4_LACLA.

Residues 68-151 are 55% similar to a (ATP-BINDING PROTEOME TRANSPORTER COMPLETE) protein domain (PD008079 which is seen in Q9CGN4_LACLA.

Residues 391-443 are 69% similar to a (ATP-BINDING ABC TRANSPORTER PROTEOME) protein domain (PD348029 which is seen in Q9CGN4_LACLA.

Residues 345-383 are 64% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000005 which is seen in Q9CGN4_LACLA.

Residues 444-486 are 81% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000006 which is seen in Q9CGN4_LACLA.

Residues 251-400 are 20% similar to a (PROTEOME BINDING COMPLETE ABC) protein domain (PD400320 which is seen in Q9CH40_LACLA.


Paralogs:  Local Blast Search
SMu1306 is paralogously related (blast p-value < 1e-3) to SMu1959, SMu0823, SMu0729, SMu0390, SMu1757, SMu1410, SMu0418, SMu0218, SMu1079, SMu1380, SMu1210, SMu0216, SMu0849, SMu0596, SMu0594, SMu0164, SMu0731, SMu1316, SMu1023, SMu1518, SMu0258, SMu0916, SMu1065, SMu0884, SMu1001, SMu1724, SMu1068, SMu0786, SMu0224, SMu1037, SMu1751, SMu1710, SMu1949, SMu1811, SMu1517, SMu0825, SMu0024, SMu1920, SMu1649, SMu0335, SMu0517, SMu1545, SMu1288, SMu1093, SMu1036, SMu0907, SMu1950, SMu0944, SMu1428, SMu1246, SMu1231, SMu0476, SMu1762, SMu0235, SMu0805, SMu1064, SMu0971, SMu0475, SMu1003, SMu0837, SMu0986, SMu0824, SMu0976, SMu1050, SMu0836, SMu0234, SMu0752, SMu1375, SMu0987, SMu0666, and SMu0374, all with ATP-binding capabilities.


Pfam Summary:  Pfam Search
Residues 29 to 235 (E-value = 1e-36) place SMu1306 in the ABC_tran family which is described as ABC transporter (PF00005)
Residues 354 to 516 (E-value = 1.8e-35) place SMu1306 in the ABC_tran family which is described as ABC transporter (PF00005)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MIILQGNKLERSFSGDVLFDNINLQVDEHDRIALVGPNGAGKSTLLKILV
GEETATSGEVTLKRDVTLSYLAQNSRFKSDNTIYDEMLHVFDDLRATERH
LRSMEGQMAELVGNDFDKLMADYDRLSESFRQQGGFTYESDIKAILNGFK
FDESMWQTKIAELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETISW
LENYLVNYQGALIIVSHDRYFLDKVATVTLDLTPHSLDRYVGNYSKFMDL
KAEKIAMKEKNYEKQQKEIAKLEDFVQRNIVRASTTKRAQARRKQLEKME
RLDKPDASKKSANMTFHVDKASGNEVLKVTDAAIGYDDKILAQPIDLDVR
KMDALAIVGPNGIGKSTLLKSIMGQIPFIHGSSVYGSNVQVGYYDQTQSN
LTASNTVLEELWSAFPRTAEVDIRNRLGAFLFSGDDVKKSVAMLSGGERA
RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLETALIDFDGTLLFVSHDR
YFINRVATKVLEISQNGSTLYLGDYDYYLEKKAEREAKTEFLQPMQSGSP
SSSLAAATNYQAQKANQKEERKLKRRIAEIEERLETIEARETEINEAMLT
TNDFTQLADLQKELESVQTEQLELLEEWEELSRQLED

Gene Nucleotide Sequence:  Sequence Viewer
ATGATTATTTTACAGGGAAACAAATTAGAGCGCTCATTTTCTGGTGATGT
GCTCTTTGATAATATTAATCTTCAAGTAGATGAACATGATCGTATCGCCT
TGGTTGGACCTAATGGTGCTGGTAAGTCTACACTCTTAAAAATTCTCGTG
GGTGAAGAAACAGCAACATCAGGTGAGGTCACTCTCAAGCGTGATGTAAC
CCTGTCGTATTTGGCTCAGAATAGCCGTTTTAAATCTGATAATACCATTT
ATGATGAAATGCTCCATGTTTTTGATGATTTACGTGCGACTGAGAGACAT
TTGCGCTCTATGGAAGGGCAAATGGCAGAGTTGGTCGGAAATGATTTTGA
TAAACTCATGGCTGATTATGACCGCTTATCCGAATCCTTCAGGCAGCAGG
GTGGTTTCACTTATGAGAGTGACATCAAAGCTATTCTCAATGGTTTTAAA
TTTGATGAGTCTATGTGGCAGACGAAAATTGCTGAACTCTCAGGCGGTCA
AAACACGCGCCTAGCTTTGGCCAAGATGCTTCTAGAAAAACCAGAACTGT
TGGTATTGGACGAGCCCACCAATCATTTGGATATTGAAACCATTTCTTGG
TTGGAAAATTATTTAGTCAATTATCAAGGAGCTTTAATCATTGTTAGTCA
TGACCGTTATTTTCTTGATAAGGTAGCGACAGTTACGCTTGATTTGACCC
CTCACTCTCTAGATCGCTATGTGGGAAATTATTCCAAATTCATGGATCTT
AAGGCTGAAAAAATTGCCATGAAAGAGAAAAATTATGAGAAGCAGCAAAA
AGAAATTGCTAAATTAGAGGACTTTGTGCAGCGCAATATTGTTCGTGCAT
CAACGACCAAGCGGGCACAGGCTAGGCGTAAGCAATTGGAAAAAATGGAG
CGATTGGATAAACCCGATGCCAGTAAAAAATCTGCCAATATGACTTTTCA
TGTTGATAAAGCCTCCGGAAATGAGGTTTTAAAGGTTACTGATGCAGCTA
TTGGTTATGATGACAAGATATTAGCGCAGCCTATTGATCTAGATGTTAGA
AAAATGGATGCCCTTGCTATCGTCGGTCCCAATGGTATTGGCAAATCAAC
CTTGCTCAAGTCCATTATGGGGCAAATACCATTTATTCATGGGAGCTCAG
TTTATGGCTCAAATGTACAAGTCGGTTATTATGACCAGACCCAATCCAAT
CTGACAGCTAGCAATACCGTTTTAGAAGAGCTTTGGTCAGCCTTTCCAAG
GACAGCAGAAGTGGATATTAGAAACCGTTTAGGTGCTTTTCTCTTTTCAG
GCGACGATGTCAAAAAATCTGTTGCCATGCTGTCTGGTGGTGAACGCGCG
CGCTTGCTTCTTGCCAAGTTATCCATGGAAAACAATAATTTTCTCATTCT
AGACGAACCTACTAATCACTTAGATATTGACAGTAAGGAAGTGTTGGAGA
CTGCTCTTATTGATTTTGATGGCACTCTTCTCTTTGTTAGCCACGACCGT
TATTTCATCAACCGCGTCGCGACAAAAGTTCTCGAAATCTCCCAAAATGG
TTCCACCCTTTACTTAGGTGATTACGATTATTATCTTGAAAAAAAAGCAG
AGCGAGAAGCAAAGACAGAGTTCCTTCAACCTATGCAGTCAGGATCCCCT
TCATCCTCCTTGGCTGCCGCCACGAACTATCAAGCCCAAAAGGCCAACCA
AAAAGAAGAACGCAAATTAAAGAGGCGTATAGCCGAAATTGAAGAGCGTT
TAGAAACCATTGAAGCGCGTGAAACTGAAATTAATGAGGCCATGCTTACT
ACTAATGACTTTACTCAATTGGCCGACCTGCAAAAAGAACTAGAAAGCGT
TCAAACAGAACAATTGGAACTTCTAGAAGAATGGGAAGAATTGAGTAGGC
AGCTGGAGGATTGA

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