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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1092 IGR1087 IGR1089 IGR1086 IGR1091 IGR1088 IGR1083 IGR1085 IGR1084 IGR1082 SMu1252 tpn, - SMu1251 leuD, - SMu1259 yqkA, - SMu1254 orfY, - SMu1250 SMu1255 leuB, - SMu1261 leuC, - SMu1260 leuA, - SMu1262 SMu1253 SMu1256 tpn, - SMu1258 SMu1252 tpn, - SMu1251 leuD, - SMu1259 yqkA, - SMu1254 orfY, - SMu1250 SMu1255 leuB, - SMu1261 leuC, - SMu1260 leuA, - SMu1262 SMu1253 SMu1256 tpn, - SMu1258 tpn, - SMu1251 leuD, - SMu1259 yqkA, - SMu1254 orfY, - SMu1250 SMu1255 leuB, - SMu1261 leuC, - SMu1260 leuA, - SMu1262 SMu1252 SMu1253 SMu1256 tpn, - SMu1258 tpn, - SMu1257 tpn, - SMu1257


LANL Gene ID: SMu1257

GenBank Locus Tag: SMU.1379

DNA Molecule Name:
1  

Genomic Island ID:
12

GenBank ID:
24379786

 Gene Name:
tpn  

 Definition:
transposase, IS861-associated, IS3 family

 Cellular Location:
Cytoplasm [Evidence]

 Gene Start:
1307343

Gene Stop:
1307861

Gene Length:
519

Molecular Weight*:
20606

pI*:
10.40

Net Charge*:
10.49

EC:
 

 Functional Class:
Mobile and extrachromosomal element functions; Transposon functions  

 Gene Ontology:
Biological process
  GO:0006313    transposition, DNA-mediated

Molecular function
  GO:0003677    DNA binding
  GO:0004803    transposase activity


 Pathway: pathway table

 Comment:


 View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to hypothetical proteins and IS861 associated segments:residues 1-108 are 73% similar to the hypothetical protein in S.pneumoniae (gi8163692) and are 62% similar to the conserved hypothetical protein, IS861 associated in S.pyogenes (gi15674401).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1526 (9e-37).


 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379046|ref|NP_721001.1|  hypothetical protein SMU.566c ...   254   2e-66
 gi|116628110|ref|YP_820729.1|  Transposase [Streptococcus th...   205   1e-51
 gi|116627004|ref|YP_819623.1|  Transposase [Streptococcus th...   205   1e-51
 gi|125717141|ref|YP_001034274.1|  ORFA, transposon ISSsa1 [S...   190   2e-47
 gi|81096535|ref|ZP_00874876.1|  IS861, transposase OrfA [Str...   189   6e-47
 gi|55822193|ref|YP_140634.1|  IS861, transposase (orf1), IS3...   187   3e-46
 gi|81097010|ref|ZP_00875327.1|  IS861, transposase OrfA [Str...   186   5e-46
 gi|149008017|ref|ZP_01831574.1|  Transposase [Streptococcus ...   186   6e-46
 gi|149006096|ref|ZP_01829825.1|  ORFA, transposon ISSsa2 [St...   185   1e-45
 gi|116626988|ref|YP_819607.1|  Transposase [Streptococcus th...   183   3e-45


InterPro Summary:  InterProScan

InterPro
IPR002514
Family
Transposase IS3/IS911
PF01527 [55-148]T 0.0065999985252638 PF01527 Transposase_8 Transposase_8
InterPro
IPR009057
Domain
Homeodomain-like
SSF46689 [3-96]T 0.0011 SSF46689 Homeodomain_like Homeodomain_like


COGS Summary:  COGS Search
No hits to the COGs database.
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 38-108 are 67% similar to a (DOMAIN OF UNKNO N) protein domain (PD354820 which is seen in Q53639_STRAG.

Residues 1-37 are 78% similar to a (DOMAIN OF UNKNO N) protein domain (PD230559 which is seen in Q9KK22_STRPN.


Paralogs:  Local Blast Search
SMu1257 is paralogously related (blast p-value < 1e-3) to SMu1720, SMu1284, SMu0694, SMu0515, and SMu0396, all predicted conserved hypotheticals,possibly transposon IS861 associated.


Pfam Summary:  Pfam Search
Residues 55 to 148 (E-value = 5.3e-06) place SMu1257 in the Transposase_8 family which is described as Transposase (PF01527)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MKLTYEDKVLIYELKNQGYSLEQLSNKFGIKISNLSYMIKLIDHYGIEIV
KKGKNRYYSPELKQEIIDKVLLEGRSQIRVSLDYALPSHGMLPNWIAQYK
KNRYTIVEKTRGRPPKMGRKPKKKSEEMTELEQLQKELEYLRAENAVLKK
LRELRLREEKEQEEKRKLSEDW

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAATTGACTTATGAAGATAAAGTTCTCATCTATGAACTGAAAAACCA
AGGGTATAGCTTAGAGCAGCTTTCAAATAAATTTGGGATAAAAATTTCTA
ATCTTAGCTACATGATTAAATTGATTGATCATTACGGAATAGAGATCGTC
AAAAAAGGAAAGAATCGTTACTATTCTCCTGAACTAAAACAAGAAATCAT
TGATAAAGTTCTTCTTGAAGGTCGTTCACAAATAAGGGTGTCTCTAGATT
ATGCTCTTCCAAGTCATGGAATGTTGCCTAATTGGATAGCACAATACAAG
AAAAATAGGTATACTATTGTTGAGAAAACAAGAGGGAGACCACCTAAAAT
GGGACGTAAGCCAAAGAAGAAATCGGAAGAAATGACAGAGCTAGAGCAAC
TTCAGAAAGAATTAGAATATCTGAGAGCGGAGAATGCTGTTCTAAAAAAG
TTGAGAGAACTCCGATTGAGGGAAGAAAAAGAGCAAGAAGAAAAACGGAA
ATTGTCCGAGGATTGGTAA

Los Alamos National Laboratory • Est 1943

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