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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap tRNA-Arg-3 IGR1007 IGR1011 IGR1014 IGR1010 IGR1012 IGR1009 gph, - SMu1168 SMu1172 SMu1170 yitG,blt, - SMu1173 rodA, - SMu1169 ezrA, - SMu1166 gyrB, - SMu1167 tnrA, - SMu1174 psaR, - SMu1171 gph, - SMu1168 SMu1172 SMu1170 yitG,blt, - SMu1173 rodA, - SMu1169 ezrA, - SMu1166 gyrB, - SMu1167 tnrA, - SMu1174 psaR, - SMu1171 gph, - SMu1168 SMu1172 SMu1170 yitG,blt, - SMu1173 rodA, - SMu1169 ezrA, - SMu1166 gyrB, - SMu1167 tnrA, - SMu1174 psaR, - SMu1171


LANL Gene ID: SMu1169

GenBank Locus Tag: SMU.1279c

DNA Molecule Name:
1  

GenBank ID:
24379698

Gene Name:
rodA  

Definition:
cell division protein; shape-determining protein

Cellular Location:
Membrane, Cytoplasm, Extracellular [Evidence]

Gene Start:
1209821

Gene Stop:
1208595

Gene Length:
1227

Molecular Weight*:
45300

pI*:
9.80

Net Charge*:
5.20

EC:
 

Functional Class:
Cellular processes; Cell division  

Gene Ontology:
Biological process
  GO:0007049    cell cycle

Cellular component
  GO:0016021    integral to membrane


Pathway: pathway table

Comment:
For other 'rod' genes see SMu0017 (rodB).



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several matches in gapped BLAST to rod shape determining protein: residues 5-393 are 62% similar to the protein in S.pneumoniae (gi15902756). Residues 9-384 are 53% similar to the protein from Lactococcus lactis (gi15672878).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0621 (1e-159).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379698|ref|NP_721653.1|  putative cell division protein...   689   0.0  
 gi|77414278|ref|ZP_00790437.1|  cell division protein, FtsW/...   505   e-141
 gi|22536794|ref|NP_687645.1|  rod shape-determining protein ...   504   e-141
 gi|116627964|ref|YP_820583.1|  cell division membrane protei...   468   e-130
 gi|55823148|ref|YP_141589.1|  cell division protein [Strepto...   465   e-129
 gi|55821236|ref|YP_139678.1|  cell division protein [Strepto...   461   e-128
 gi|146319166|ref|YP_001198878.1|  Rod shape determining prot...   455   e-126
 gi|20502756|gb|AAM22611.1|AF399832_1  RodA [Streptococcus th...   454   e-126
 gi|15902756|ref|NP_358306.1|  Rod shape determining protein ...   448   e-124
 gi|15900696|ref|NP_345300.1|  rod shape-determining protein ...   448   e-124


InterPro Summary:  InterProScan

InterPro
IPR001182
Family
Cell cycle protein
PF01098 [13-388]T 2.8999780742320708E-68 PF01098 FTSW_RODA_SPOVE FTSW_RODA_SPOVE
PS00428 [344-368]T 8.0E-5 PS00428 FTSW_RODA_SPOVE FTSW_RODA_SPOVE


COGS Summary:  COGS Search
BeTs to 11 clades of COG0772
COG name: Bacterial cell division membrane protein FtsW/MrdB/SpoVE
Functional Class: D
The phylogenetic pattern of COG0772 is -----QVcEBRHUJ--OLINX
Number of proteins in this genome belonging to this COG is 2
Blocks Summary:  Blocks Search
***** IPB001182 (Cell cycle proteins) with a combined E-value of 3.2e-40.
    IPB001182A    103-120
    IPB001182B    252-273
    IPB001182C    278-299
    IPB001182D    343-368


 ProDom Summary:  Protein Domain Search
Residues 1-47 are 51% similar to a (3'REGION GTFK) protein domain (PD244500 which is seen in Q00605_STRSL.

Residues 16-381 are 53% similar to a (CELL DIVISION COMPLETE PROTEOME) protein domain (PD003242 which is seen in Q9CH43_LACLA.


Paralogs:  Local Blast Search
SMu1169 is paralogously related (blast p-value < 1e-3) to SMu0650, a predicted cell division protein FtsW.


Pfam Summary:  Pfam Search
Residues 13 to 388 (E-value = 2.6e-71) place SMu1169 in the FTSW_RODA_SPOVE family which is described as Cell cycle protein (PF01098)

 Structural Feature(s):
Feature Type  Start  Stop
cleavable  
1  
35
transmembrane  
51  
67
transmembrane  
79  
95
transmembrane  
152  
168
transmembrane  
176  
192
transmembrane  
201  
217
transmembrane  
295  
311
transmembrane  
333  
349

Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MASKKKPIDSRVDYSLILPVFFLVLIGLFSVYTATIHDYPSKIMVVMGQQ
LIWLIMGAAISFVVMLFSTEFLWKITPYLYGLGLILMIFPLIFYSPELVA
STGAKNWVSIGSVTLFQPSEFMKISYILILARLTVTFKQKYKEKNLQEDG
KLLLWFALLTLPIMILLALQKDLGTAMVFMAILAGLVLIAGISWQIILPV
VGAVALIVALFMVVFLIPGGKEFLYHHMGVDTYQINRLSAWLNPFDYAGS
IAYQQTQGMISIGSGGLFGKGFNIVELPVPVRESDMIFTVIAENFGFIGG
SIVLALYLILIYRMLRVTFASNNLFYTYISTGFIMMILFHIFENIGAAVG
ILPLTGIPLPFISQGGSSLISNLIGVGLVLSMSYQNSLNQEKATERYFAH
IKKESLTS

Gene Nucleotide Sequence:  Sequence Viewer
ATGGCAAGCAAAAAAAAGCCGATTGATAGTCGGGTGGATTATTCTCTTAT
TTTACCAGTTTTCTTTTTAGTTTTGATAGGACTTTTCTCTGTTTATACAG
CGACAATTCACGACTATCCTAGTAAAATTATGGTCGTGATGGGACAACAG
TTGATTTGGTTGATTATGGGAGCTGCTATTAGTTTTGTTGTCATGCTCTT
TAGTACAGAATTCCTTTGGAAAATCACTCCTTATTTATATGGCTTAGGGT
TAATTTTAATGATTTTTCCTTTGATCTTTTACAGTCCTGAATTAGTTGCT
TCGACGGGTGCTAAAAACTGGGTTTCCATTGGTTCAGTGACCTTATTTCA
GCCTTCGGAGTTTATGAAAATTTCCTATATCTTAATTTTAGCACGCTTAA
CGGTCACTTTTAAACAAAAGTATAAAGAAAAGAATTTGCAAGAAGATGGG
AAACTTTTACTCTGGTTTGCATTGTTAACACTGCCTATTATGATTCTTTT
AGCTTTGCAAAAAGATTTGGGAACTGCTATGGTTTTTATGGCTATTTTAG
CTGGTCTGGTATTAATCGCAGGTATCTCTTGGCAGATTATTTTGCCAGTC
GTCGGTGCTGTTGCCTTGATAGTTGCTCTTTTTATGGTTGTTTTTTTAAT
TCCTGGTGGTAAGGAATTTCTCTATCATCATATGGGAGTAGATACCTATC
AAATTAATCGTCTCTCAGCTTGGCTAAATCCCTTTGATTATGCTGGTAGC
ATTGCTTACCAACAAACTCAAGGCATGATTTCGATTGGTAGTGGTGGCTT
ATTTGGAAAGGGCTTTAACATTGTTGAACTTCCTGTTCCTGTCCGTGAAA
GTGATATGATTTTTACAGTCATTGCTGAGAATTTTGGCTTTATTGGCGGC
AGTATTGTGTTAGCCCTCTATTTAATTCTTATTTATCGTATGCTGCGTGT
CACTTTTGCGTCAAACAATCTGTTTTATACTTATATTTCAACTGGTTTTA
TTATGATGATTCTTTTCCATATTTTTGAGAACATTGGAGCAGCAGTTGGT
ATCTTACCTTTAACAGGTATTCCGCTTCCTTTTATTTCCCAAGGAGGAAG
TTCCTTGATTTCCAATTTGATTGGTGTTGGATTGGTCTTGTCTATGTCTT
ATCAAAATAGTCTCAATCAGGAAAAAGCCACAGAACGCTATTTTGCTCAT
ATCAAAAAGGAGAGTCTTACAAGTTAA

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