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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR658 IGR657 IGR662 IGR659 IGR660 IGR661 ycgG, - SMu0761 gtrB,ybaI, - SMu0757 SMu0758 SMu0756 SMu0760 SMu0759 SMu0755 ycgG, - SMu0761 gtrB,ybaI, - SMu0757 SMu0758 SMu0756 SMu0760 SMu0759 SMu0755 ycgG, - SMu0761 gtrB,ybaI, - SMu0757 SMu0758 SMu0756 SMu0760 SMu0759 SMu0755


LANL Gene ID: SMu0758

GenBank Locus Tag: SMU.834

DNA Molecule Name:
1  

GenBank ID:
24379289

Gene Name:


Definition:
glycosyltransferase

Cellular Location:
Membrane, Cytoplasm [Evidence]

Gene Start:
782537

Gene Stop:
783475

Gene Length:
939

Molecular Weight*:
35767

pI*:
6.60

Net Charge*:
-1.07

EC:
 

Functional Class:
Unassigned  

Gene Ontology:

Pathway: pathway table

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to unknowns and glycosyltransferase: residues 1-309 are 61% similar to an unknown in Listeria monocytogenes (gi4104144).Residues 4-309 are 63% similar to the enzyme in Clostridium acetobutylicum (gi15895591).






The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1421 (2e-13).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379289|ref|NP_721244.1|  hypothetical protein SMU.834 [...   615   e-174
 gi|30024646|dbj|BAC75700.1|  hypothetical protein [Streptoco...   526   e-148
 gi|69250238|ref|ZP_00605123.1|  Glycosyl transferase, family...   423   e-117
 gi|46908940|ref|YP_015329.1|  glycosyl transferase, group 2 ...   390   e-107
 gi|15895591|ref|NP_348940.1|  Glycosyltransferase [Clostridi...   390   e-107
 gi|153814635|ref|ZP_01967303.1|  hypothetical protein RUMTOR...   326   1e-87
 gi|156868174|gb|EDO61546.1|  hypothetical protein CLOLEP_019...   323   9e-87
 gi|119026523|ref|YP_910368.1|  possible glycosyltransferase ...   321   3e-86
 gi|139439704|ref|ZP_01773095.1|  Hypothetical protein COLAER...   311   4e-83
 gi|148643350|ref|YP_001273863.1|  glycosyltransferase [Metha...   310   9e-83


InterPro Summary:  InterProScan

InterPro
IPR001173
Domain
Glycosyl transferase, family 2
PF00535 [6-161]T 3.39999972437687E-19 PF00535 Glycos_transf_2 Glycos_transf_2
noIPR
unintegrated
unintegrated
G3DSA:3.90.550.10 [4-208]T 2.70000183580793E-10 G3DSA:3.90.550.10 G3DSA:3.90.550.10 G3DSA:3.90.550.10
PTHR10859 [11-308]T 9.10000425645606E-25 PTHR10859 PTHR10859 PTHR10859
SSF53448 [4-206]T 3.6E-18 SSF53448 SSF53448 SSF53448


COGS Summary:  COGS Search
BeTs to 10 clades of COG0463
COG name: Glycosyltransferases involved in cell wall biogenesis
Functional Class: M
The phylogenetic pattern of COG0463 is AMTKYQVCEBRHujGPo---X
Number of proteins in this genome belonging to this COG is 5
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 5-68 are 73% similar to a (TRANSFERASE COMPLETE PROTEOME GLYCOSYLTRANSFERASE) protein domain (PD000196 which is seen in Q9ZIC5_LISMO.

Residues 69-139 are 42% similar to a (PROTEOME COMPLETE RFBJ) protein domain (PD350147 which is seen in P73444_SYNY3.

Residues 223-295 are 46% similar to a (PROTEOME RFBJ-GND COMPLETE ORF10X9) protein domain (PD021486 which is seen in Q9ZIC5_LISMO.

Residues 72-116 are 60% similar to a (PROTEOME COMPLETE TRANSFERASE) protein domain (PD263808 which is seen in Q9ZIC5_LISMO.

Residues 139-220 are 67% similar to a (PROTEOME COMPLETE SYNTHASE MANNOSE) protein domain (PD336873 which is seen in Q9ZIC5_LISMO.

Residues 55-217 are 26% similar to a (PROTEOME COMPLETE) protein domain (PD086719 which is seen in P72930_SYNY3.

Residues 143-207 are 43% similar to a (TRANSFERASE SYNTHASE PROTEOME) protein domain (PD001307 which is seen in O29860_ARCFU.


Paralogs:  Local Blast Search
SMu0758 is paralogously related (blast p-value < 1e-3) to SMu0757, a predicted glycosil transferase, SMu1876,a predicted stress response protein (glycosyltransferase) (sugar transferase), SMu1308,a predicted conserved hypothetical protein,possible glycosil transferase and SMu0750, a predicted rhamnosyltransferase.


Pfam Summary:  Pfam Search
Residues 6 to 165 (E-value = 5.5e-20) place SMu0758 in the Glycos_transf_2 family which is described as Glycosyl transferase (PF00535)

 Structural Feature(s):
Feature Type  Start  Stop
transmembrane  
231  
247
transmembrane  
267  
283

Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MTEKIAILLPAYNEEITIQKVISDFKRVLPEADIYVYDNNSKDRTNELAR
QAGAIVRFESRQGKGNVVRSMFREINADYYIMVDADDTYPADEVQKLLDP
LRSGKADMTIGDRLSNGTYAEENKRGFHGFGNNLVRLLVNHLYQGNYQDI
MTGYRGFNRLFVKNFPVLSSGFEIETELSIHSLDKRFKLVEVPITYHDRP
EGSESKLNTFSDGFKVLCMIFNLFKDYKPLIFFSLVTLFFFILGLIVGVP
VVTEFAETGFIAKMPSAILATGFMILAALSFALGFILDTIVRQNRMQYEL
KIYDYYERNGRK

Gene Nucleotide Sequence:  Sequence Viewer
ATGACAGAGAAAATTGCAATATTACTTCCAGCTTACAATGAAGAGATTAC
TATTCAAAAAGTTATCTCTGATTTTAAGCGAGTCTTACCGGAAGCTGACA
TTTATGTTTATGATAATAATTCTAAAGACAGAACAAATGAATTAGCTCGT
CAAGCTGGTGCGATTGTTCGTTTTGAATCTCGTCAAGGAAAGGGAAATGT
TGTTCGTTCAATGTTTCGTGAAATTAATGCAGATTACTATATCATGGTTG
ATGCAGATGATACCTACCCAGCAGACGAGGTGCAAAAGCTTTTAGATCCT
TTACGTTCTGGTAAAGCTGATATGACCATTGGAGATCGTCTATCTAATGG
GACTTATGCTGAAGAAAATAAGCGTGGGTTTCATGGCTTCGGCAATAATT
TAGTACGACTTTTAGTTAATCACCTTTACCAAGGAAATTATCAGGATATT
ATGACGGGATATCGTGGCTTTAATCGTCTCTTTGTTAAGAATTTTCCTGT
CTTATCATCAGGATTCGAGATTGAGACTGAATTGTCAATCCATTCGCTTG
ACAAACGTTTTAAACTAGTCGAAGTGCCTATTACATATCATGATCGTCCC
GAGGGCAGTGAATCTAAACTGAATACCTTCTCGGATGGTTTTAAAGTACT
TTGTATGATTTTTAATCTCTTTAAAGATTATAAGCCACTCATATTCTTTA
GTCTTGTGACTTTATTTTTCTTTATTTTAGGTCTTATCGTAGGTGTTCCT
GTTGTGACGGAATTTGCAGAAACAGGCTTTATTGCTAAAATGCCATCAGC
TATTTTAGCAACAGGTTTTATGATTTTAGCAGCCTTGTCTTTTGCGTTAG
GTTTTATTTTAGATACTATTGTTCGTCAGAATCGTATGCAATATGAACTG
AAAATTTATGACTATTATGAGCGTAATGGCCGTAAATAG

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