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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR569 IGR573 IGR574 IGR572 IGR575 IGR568 IGR571 IGR567 SMu0655 murM, - SMu0654 murN,fibB,femB, - SMu0653 SMu0656 SMu0659 SMu0658 tpiA, - SMu0652 SMu0657 tufA,tuf, - SMu0651 pacL, - SMu0660 SMu0655 murM, - SMu0654 murN,fibB,femB, - SMu0653 SMu0656 SMu0659 SMu0658 tpiA, - SMu0652 SMu0657 tufA,tuf, - SMu0651 pacL, - SMu0660 SMu0655 murM, - SMu0654 murN,fibB,femB, - SMu0653 SMu0656 SMu0658 tpiA, - SMu0652 SMu0657 tufA,tuf, - SMu0651 pacL, - SMu0660 SMu0659


LANL Gene ID: SMu0655

GenBank Locus Tag: SMU.718c

DNA Molecule Name:
1  

GenBank ID:
24379186

Gene Name:


Definition:
hydrolase, haloacid dehalogenase-like family

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
678586

Gene Stop:
677777

Gene Length:
810

Molecular Weight*:
29798

pI*:
5.20

Net Charge*:
-6.78

EC:
 

Functional Class:
Unassigned  

Gene Ontology:
Biological process
  GO:0008152    metabolic process

Molecular function
  GO:0003824    catalytic activity
  GO:0016787    hydrolase activity


Pathway: pathway table

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to conserved hypothetical proteins: residues 1-268 are 76% similar to the protein in S.pneumoniae (gi15903213).Residues 1-269 are 71% similar to the protein in S.pyogenes (gi15674695).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0511 (1e-121).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379186|ref|NP_721141.1|  hypothetical protein SMU.718c ...   496   e-139
 gi|15903213|ref|NP_358763.1|  hypothetical protein spr1170 [...   411   e-113
 gi|149002666|ref|ZP_01827598.1|  hypothetical protein CGSSp1...   411   e-113
 gi|149019290|ref|ZP_01834652.1|  hypothetical protein CGSSp2...   409   e-112
 gi|148994102|ref|ZP_01823442.1|  Cof family protein [Strepto...   409   e-112
 gi|149007041|ref|ZP_01830710.1|  Cof family protein [Strepto...   407   e-112
 gi|148989316|ref|ZP_01820696.1|  hypothetical protein CGSSp6...   406   e-112
 gi|15901151|ref|NP_345755.1|  Cof family protein [Streptococ...   406   e-112
 gi|148985191|ref|ZP_01818430.1|  hypothetical protein CGSSp3...   405   e-111
 gi|157076294|gb|ABV10977.1|  Cof family protein [Streptococc...   402   e-110


InterPro Summary:  InterProScan

InterPro
IPR000150
Family
Cof protein
TIGR00099 [5-263]T 1.02248781753829E-81 TIGR00099 Cof-subfamily Cof-subfamily
PS01228 [5-16]T 8.0E-5 PS01228 COF_1 COF_1
InterPro
IPR006379
Family
HAD-superfamily hydrolase, subfamily IIB
TIGR01484 [5-236]T 8.022781791363329E-25 TIGR01484 HAD-SF-IIB HAD-SF-IIB
InterPro
IPR013200
Domain
HAD superfamily hydrolase-like, type 3
PF08282 [6-263]T 4.60000044330908E-95 PF08282 Hydrolase_3 Hydrolase_3
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.1000 [2-267]T 1.4000050690730897E-48 G3DSA:3.40.50.1000 G3DSA:3.40.50.1000 G3DSA:3.40.50.1000
PTHR21485 [203-254]T 1.1000002989614898E-8 PTHR21485 PTHR21485 PTHR21485
PTHR21485:SF10 [203-254]T 1.1000002989614898E-8 PTHR21485:SF10 PTHR21485:SF10 PTHR21485:SF10
SSF56784 [1-268]T 2.0000000000000002E-71 SSF56784 SSF56784 SSF56784


COGS Summary:  COGS Search
BeTs to 12 clades of COG0561
COG name: Predicted hydrolases of the HAD superfamily
Functional Class: R
The phylogenetic pattern of COG0561 is a-tky-vCEBrH--GPOlin-
Number of proteins in this genome belonging to this COG is 11
Blocks Summary:  Blocks Search
***** IPB000150 (Cof protein) with a combined E-value of 6.9e-27.
    IPB000150A    2-16
    IPB000150B    36-45
    IPB000150C    215-247


 ProDom Summary:  Protein Domain Search
Residues 3-86 are 29% similar to a (PROTEOME COMPLETE) protein domain (PD201280 which is seen in O83314_TREPA.

Residues 4-228 are 27% similar to a (RNPA-LICA R4 ORF) protein domain (PD107065 which is seen in YRR4_MYCCA.

Residues 3-45 are 65% similar to a (PROTEOME COMPLETE SIPU BH0497) protein domain (PD306139 which is seen in Q9CGM1_LACLA.

Residues 46-187 are 57% similar to a (PROTEOME COMPLETE YKIF IBPA-GYRB) protein domain (PD034656 which is seen in Q9CGM1_LACLA.

Residues 4-45 are 50% similar to a (COMPLETE PROTEOME BU028 PLDB-METR) protein domain (PD388374 which is seen in Q9KS95_VIBCH.

Residues 193-247 are 70% similar to a (PROTEOME COMPLETE HYDROLASE ATPASE) protein domain (PD001342 which is seen in Q9CGM1_LACLA.

Residues 4-115 are 28% similar to a (PROTEOME COMPLETE MG265 VCA0243) protein domain (PD002063 which is seen in Q9CLI7_PASMU.


Paralogs:  Local Blast Search
SMu0655 is paralogously related (blast p-value < 1e-3) to SMu0675, SMu0388, SMu1666, SMu0461, SMu0367, SMu0442, SMu1012, and SMu0674,all predicted conserved hypothetical proteins.


Pfam Summary:  Pfam Search
Residues 3 to 240 (E-value = 1.2e-05) place SMu0655 in the Hydrolase family which is described as haloacid dehalogenase-like hydrolase (PF00702)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MSIKLVAVDIDGTLLNSKREVTPEVYTAIQDAKKAGVKVVIATGRPIAGV
TDLLEKLNLKDQGDYVITFNGALVQDTATGEDLIKETLTYDDYLDIELLS
RKLGVHMHAISKEGIYTANRDIGKYTVHEASLVNMPVYYRTPEEMVGKEI
VKIMMIDEPEMLDAAIAQLPASLYEHYTVVKSRPFYLEIMNKKVSKGTAI
VHLAEKLGLSRDETMAIGDEENDRAMLEAVGSPVVMENGIPELKKMAKYI
TKSNDNSGVAYAIKKWVLN

Gene Nucleotide Sequence:  Sequence Viewer
ATGTCAATTAAATTGGTTGCTGTCGATATTGACGGCACATTACTTAATAG
TAAGCGTGAAGTAACACCTGAAGTTTACACTGCTATCCAAGATGCTAAAA
AAGCCGGCGTCAAGGTCGTTATTGCAACAGGCCGCCCCATTGCTGGTGTA
ACCGATTTACTAGAAAAATTAAATCTCAAGGATCAAGGAGATTACGTGAT
TACTTTTAACGGTGCTTTAGTACAAGATACCGCAACTGGTGAAGACTTGA
TTAAAGAAACGTTAACTTATGATGATTATTTAGATATTGAATTGCTCAGT
CGCAAATTAGGTGTGCACATGCATGCTATCTCTAAAGAAGGTATTTACAC
TGCCAATCGTGATATCGGCAAATACACTGTCCATGAAGCAAGTTTGGTTA
ACATGCCAGTCTATTATCGTACTCCTGAAGAAATGGTTGGCAAAGAGATT
GTGAAAATAATGATGATTGACGAACCTGAAATGTTAGATGCTGCTATTGC
TCAACTGCCAGCCAGCCTTTATGAACACTACACAGTTGTCAAATCAAGAC
CTTTTTATTTAGAAATCATGAATAAAAAAGTCAGCAAAGGCACTGCTATC
GTTCATTTAGCAGAAAAGTTAGGACTTAGCAGAGATGAGACAATGGCTAT
TGGTGATGAGGAAAATGATCGTGCTATGCTAGAAGCTGTTGGAAGCCCTG
TTGTGATGGAAAATGGTATTCCTGAACTCAAAAAAATGGCTAAGTACATC
ACCAAATCAAACGACAACAGTGGGGTCGCTTATGCAATTAAAAAGTGGGT
ATTAAACTAA

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