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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR457 IGR460 IGR459 IGR461 IGR458 IGR456 SMu0537 SMu0538 lytS, - SMu0526 hlpA,hslA, - SMu0536 argR,ahrC, - SMu0531 SMu0534 ispA,fps, - SMu0529 xseA, - SMu0527 recN, - SMu0532 SMu0537 SMu0538 lytS, - SMu0526 hlpA,hslA, - SMu0536 argR,ahrC, - SMu0531 SMu0534 ispA,fps, - SMu0529 xseA, - SMu0527 recN, - SMu0532 SMu0537 SMu0538 lytS, - SMu0526 hlpA,hslA, - SMu0536 argR,ahrC, - SMu0531 SMu0534 ispA,fps, - SMu0529 xseA, - SMu0527 recN, - SMu0532 xseB, - SMu0528 SMu0535 hlyX, - SMu0530 SMu0533 xseB, - SMu0528 hlyX, - SMu0530 SMu0533 SMu0535


LANL Gene ID: SMu0532

GenBank Locus Tag: SMU.585

DNA Molecule Name:
1  

GenBank ID:
24379063

Gene Name:
recN  

Definition:
DNA repair and genetic recombination protein

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
545092

Gene Stop:
546750

Gene Length:
1659

Molecular Weight*:
62730

pI*:
5.20

Net Charge*:
-17.55

EC:
 

Functional Class:
DNA metabolism; DNA replication, recombination, and repair  

Gene Ontology:
Biological process
  GO:0006259    DNA metabolic process
  GO:0006281    DNA repair
  GO:0006310    DNA recombination

Cellular component
  GO:0005694    chromosome

Molecular function
  GO:0005524    ATP binding


Pathway: pathway table

Secondary Evidence:
Van Hoy,B.E. and Hoch,J.A.
Characterization of the spoIVB and recN loci of Bacillus subtilis
J. Bacteriol. 172 (3), 1306-1311 (1990)
PubMed: 2106508


Comment:
For other 'rec' genes see SMu0021 (recO);SMu0545 (recM); SMu0545 (recR); SMu1956 (recF); SMu1892 (recA); SMu0425 (recU) ; SMu1669 (recG); SMu1705 (recD) and SMu1339 (recJ).


From Genbank: [gi:132256]
This protein may be involved in recombinational repair of damaged DNA.



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several matches in gapped BLAST to DNA repair and genetic recombination proteins: residues 1-551 are 72% similar to the protein in S.pneumoniae (gi15903127).Residues 1-552 are 69% similar to the protein in S.pyogenes (gi15675399).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0501 (0.0).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379063|ref|NP_721018.1|  DNA repair protein RecN [Strep...   990   0.0  
 gi|116627946|ref|YP_820565.1|  ATPase involved in DNA repair...   753   0.0  
 gi|55823132|ref|YP_141573.1|  DNA repair and genetic recombi...   752   0.0  
 gi|55821220|ref|YP_139662.1|  DNA repair and genetic recombi...   751   0.0  
 gi|125717534|ref|YP_001034667.1|  DNA repair and genetic rec...   745   0.0  
 gi|81096215|ref|ZP_00874563.1|  DNA repair protein RecN [Str...   741   0.0  
 gi|146319305|ref|YP_001199017.1|  ATPase involved in DNA rep...   741   0.0  
 gi|15903127|ref|NP_358677.1|  DNA repair and genetic recombi...   739   0.0  
 gi|148985096|ref|ZP_01818335.1|  DNA repair protein RecN [St...   738   0.0  
 gi|148993812|ref|ZP_01823214.1|  DNA repair protein RecN [St...   738   0.0


InterPro Summary:  InterProScan

InterPro
IPR003395
Domain
SMC protein, N-terminal
PF02463 [1-513]T 1.40000045763982E-7 PF02463 SMC_N SMC_N
InterPro
IPR004604
Family
DNA repair protein RecN
TIGR00634 [1-552]T 0.0 TIGR00634 recN recN
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [1-183]T 5.5000054650998E-13 G3DSA:3.40.50.300 G3DSA:3.40.50.300[404-533]T 1.79999951654676E-8 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR18937 [20-114]T 8.200004068084651E-5 PTHR18937 PTHR18937 PTHR18937
PTHR18937:SF10 [20-114]T 8.200004068084651E-5 PTHR18937:SF10 PTHR18937:SF10 PTHR18937:SF10
SSF52540 [2-506]T 2.2000000000000004E-43 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 8 clades of COG0497
COG name: ATPases involved in DNA repair
Functional Class: L
The phylogenetic pattern of COG0497 is -----q-cebrhuj---l--x
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 94-149 are 50% similar to a (REPAIR DNA COMPLETE PROTEOME) protein domain (PD036511 which is seen in Q9CNU3_PASMU.

Residues 165-387 are 32% similar to a (REPAIR DNA ATP-BINDING RECOMBINATION) protein domain (PD008454 which is seen in RECN_BACSU.

Residues 1-149 are 42% similar to a (DNA REPAIR ATP-BINDING RECOMBINATION) protein domain (PD348650 which is seen in RECN_VIBCH.

Residues 49-152 are 34% similar to a (REPAIR DNA ATP-BINDING RECN) protein domain (PD395165 which is seen in RECN_SYNY3.

Residues 165-387 are 36% similar to a (COIL COILED MYOSIN CHAIN ATP-BINDING HEAVY FILAMENT) protein domain (PD000002 which is seen in Q9CH78_LACLA.

Residues 389-550 are 72% similar to a (REPAIR DNA ATP-BINDING RECOMBINATION) protein domain (PD033003 which is seen in Q9CH78_LACLA.


Paralogs:  Local Blast Search
SMu0532 is paralogously related (blast p-value < 1e-3) to SMu1375, a predicted chromosome segregation SMC protein.


Pfam Summary:  Pfam Search
Residues 1 to 151 (E-value = 6.8e-06) place SMu0532 in the SMC_N family which is described as RecF/RecN/SMC N terminal domain (PF02463)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MLLEIAIKNFAIIEEISLNFERGMTVLTGETGAGKSIVIDAMNMMLGSRA
SIDVIRHGSPKAEIEGFFSVDKNPSLEQLLADQGIAFSDELIIRREILQN
GRSISRINGQMVNLATLRAVGQYLVDIHGQHDQEELMRPQKHIQLLDEFG
DEVFQVSKQHYQDLFDHYRDLRKRVLNKRKNEQEHQARIEMLEYQIGEIE
AANLQSGEDTKLLKQRDKLMNHKLIVDTLTNAYVLLDNEDFSSLTNVRSA
MNDLQSLEEYDAEYKDLSNNLSESYYILEDVSKRLETILDHMDFDANTLV
KLEARLDVINTITRKYGGSVDDVLAYFDNISKEYNHLTVNDLAFDDMERE
LKVLERSLLEAAAQLSQKRHAIAETLSQEIKQELKDLYMDKADFKVVFTK
GKFNREGNETVAFHISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRRE
DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGNHGQVLAISHIPQVIAISDY
QYFIEKQSSKATTVSTVRLLNQEERIEEIAKMLAGDNVTQAARQQAKELL
KK

Gene Nucleotide Sequence:  Sequence Viewer
ATGCTTTTAGAAATTGCCATTAAAAATTTTGCTATTATTGAAGAAATCTC
ACTCAATTTTGAAAGGGGAATGACTGTTCTGACCGGTGAAACAGGTGCAG
GGAAGTCTATTGTCATTGATGCCATGAATATGATGCTAGGCAGTAGAGCC
AGCATAGATGTCATTCGTCATGGTAGTCCTAAAGCAGAGATTGAGGGTTT
TTTCTCTGTGGATAAAAATCCTTCTTTAGAGCAGTTACTGGCTGATCAGG
GAATTGCTTTTTCAGATGAGCTAATCATTCGCCGTGAGATTTTACAAAAT
GGTCGCAGTATTAGTCGTATCAATGGTCAAATGGTTAATCTGGCAACTCT
GCGTGCCGTTGGGCAGTATTTAGTTGATATTCATGGACAGCATGATCAAG
AAGAACTGATGCGGCCGCAAAAGCATATTCAGTTGTTGGATGAATTTGGT
GATGAGGTATTTCAGGTAAGCAAGCAGCATTATCAGGACTTATTTGACCA
CTATCGGGACTTACGTAAGCGCGTCTTGAATAAACGTAAGAATGAGCAAG
AACATCAAGCACGTATTGAAATGCTGGAGTATCAGATAGGAGAGATTGAA
GCAGCAAACTTACAATCTGGTGAGGATACCAAGCTCTTAAAACAACGTGA
TAAACTTATGAATCATAAGCTTATTGTTGATACCTTAACCAATGCTTATG
TTTTACTTGATAATGAAGATTTTTCGAGTTTGACCAATGTTCGTTCAGCT
ATGAATGATTTGCAGAGTTTGGAAGAATATGATGCTGAGTACAAGGATTT
ATCCAATAATCTCAGCGAATCTTACTATATTTTAGAAGATGTTAGCAAAC
GTCTAGAGACTATACTGGATCATATGGATTTTGATGCCAATACTTTGGTT
AAACTTGAAGCACGTCTTGATGTTATCAACACCATCACGCGTAAGTATGG
TGGTTCAGTTGATGATGTTTTGGCTTATTTTGACAATATCAGTAAGGAAT
ACAATCATTTGACGGTAAATGACCTCGCTTTTGATGATATGGAAAGAGAA
CTAAAAGTTTTGGAGCGCTCACTATTAGAAGCAGCAGCTCAATTGAGTCA
AAAACGCCATGCCATTGCGGAAACCTTGTCTCAGGAGATTAAGCAGGAAC
TAAAAGATCTCTACATGGATAAGGCTGATTTTAAAGTTGTTTTTACTAAA
GGAAAATTTAATCGCGAGGGAAATGAAACAGTCGCTTTCCATATTTCGAC
TAATCCTGGCGAAGACTTTAAGCCTTTGGTCAAAGTCGCTTCTGGTGGAG
AGCTGTCTCGTCTCATGTTAGCCATTAAGTCAGCTTTTTCACGTCGTGAA
GATAAGACTAGCATTGTTTTTGATGAAGTTGATACAGGTGTTTCAGGACG
TGTCGCTCAGGCTATTGCTCAAAAAATTTACAAAATAGGCAATCACGGTC
AAGTTTTAGCTATTTCCCATATCCCGCAAGTCATTGCCATCAGTGATTAT
CAGTACTTTATTGAAAAACAAAGCAGCAAAGCCACAACTGTCTCAACGGT
TCGCCTTTTAAATCAAGAGGAAAGAATTGAAGAAATCGCTAAGATGTTGG
CAGGGGATAATGTGACCCAAGCTGCGCGCCAGCAAGCTAAAGAACTATTA
AAAAAATAA

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