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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1695 IGR8 IGR4 IGR6 IGR1.1 IGR3 IGR1 IGR2 SMu0009 SMu0003 divIC, - SMu0008 spoVC,pth, - SMu0005 smc, - SMu1964 SMu0004 dnaN, - SMu0002 SMu0010 dnaA, - SMu0001 trcF,mfd, - SMu0006 SMu0009 SMu0003 divIC, - SMu0008 spoVC,pth, - SMu0005 smc, - SMu1964 SMu0004 dnaN, - SMu0002 SMu0010 dnaA, - SMu0001 trcF,mfd, - SMu0006 SMu0003 spoVC,pth, - SMu0005 SMu0004 dnaN, - SMu0002 SMu0010 dnaA, - SMu0001 trcF,mfd, - SMu0006 SMu0007 divIC, - SMu0008 SMu0009 SMu0007


LANL Gene ID: SMu0005

GenBank Locus Tag: SMU.07

DNA Molecule Name:
1  

Genomic Island ID:
1

GenBank ID:
24378537

 Gene Name:
spoVC  pth  

 Definition:
peptidyl-tRNA hydrolase

 Cellular Location:
Cytoplasm [Evidence]

 Gene Start:
4663

Gene Stop:
5232

Gene Length:
570

Molecular Weight*:
21462

pI*:
10.20

Net Charge*:
7.72

EC:
 

 Functional Class:
Protein synthesis; tRNA and rRNA base modification  

 Gene Ontology:
Biological process
  GO:0006412    translation

Molecular function
  GO:0004045    aminoacyl-tRNA hydrolase activity


 Pathway: pathway table

 Comment:


 View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
This sequence corresponds to Spy0007.







The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0007 (3e-86).


 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24378537|ref|NP_720492.1|  peptidyl-tRNA hydrolase [Strep...   353   3e-96
 gi|22536192|ref|NP_687043.1|  peptidyl-tRNA hydrolase [Strep...   287   2e-76
 gi|77407704|ref|ZP_00784459.1|  peptidyl-tRNA hydrolase [Str...   285   6e-76
 gi|77411304|ref|ZP_00787653.1|  peptidyl-tRNA hydrolase [Str...   285   7e-76
 gi|76787164|ref|YP_328734.1|  peptidyl-tRNA hydrolase [Strep...   283   3e-75
 gi|55820108|ref|YP_138550.1|  peptidyl-tRNA hydrolase [Strep...   281   1e-74
 gi|157075952|gb|ABV10635.1|  peptidyl-tRNA hydrolase [Strept...   280   2e-74
 gi|125716893|ref|YP_001034026.1|  Peptidyl-tRNA hydrolase, p...   278   1e-73
 gi|149003145|ref|ZP_01828054.1|  peptidyl-tRNA hydrolase [St...   259   6e-68
 gi|15899954|ref|NP_344558.1|  peptidyl-tRNA hydrolase [Strep...   259   7e-68


InterPro Summary:  InterProScan

InterPro
IPR001328
Family
Peptidyl-tRNA hydrolase
PD005324 [70-135]T 0.0 PD005324 PeptRNAhydrolase PeptRNAhydrolase
G3DSA:3.40.50.1470 [4-188]T 1.30000495407324E-64 G3DSA:3.40.50.1470 Pept_tRNA_hydro Pept_tRNA_hydro
PTHR17224 [1-189]T 2.1000026783402506E-67 PTHR17224 Pept_tRNA_hydro Pept_tRNA_hydro
PF01195 [4-188]T 2.39999798157241E-74 PF01195 Pept_tRNA_hydro Pept_tRNA_hydro
TIGR00447 [2-189]T 7.581289011661831E-76 TIGR00447 pth pth
PS01195 [15-28]T 8.0E-5 PS01195 PEPT_TRNA_HYDROL_1 PEPT_TRNA_HYDROL_1
PS01196 [109-119]T 8.0E-5 PS01196 PEPT_TRNA_HYDROL_2 PEPT_TRNA_HYDROL_2
SSF53178 [1-188]T 3.1000000000000006E-65 SSF53178 Pept_tRNA_hydro Pept_tRNA_hydro


COGS Summary:  COGS Search
BeTs to 13 clades of COG0193
COG name: Peptidyl-tRNA hydrolase
Functional Class: J
The phylogenetic pattern of COG0193 is ----yqvcebrhujgpolinx
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
***** IPB001328 (Peptidyl-tRNA hydrolase) with a combined E-value of 1.8e-48.
    IPB001328A    4-23
    IPB001328B    60-71
    IPB001328C    88-119
    IPB001328D    128-138


 ProDom Summary:  Protein Domain Search
Residues 1-188 are 55% similar to a (HYDROLASE PEPTIDYL-TRNA SPORULATION) protein domain (PD005324 which is seen in PTH_LACLA.


Paralogs:  Local Blast Search
SMu0005 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search
Residues 4 to 188 (E-value = 2.1e-77) place SMu0005 in the Pept_tRNA_hydro family which is described as Peptidyl-tRNA hydrolase (PF01195)

 Top PDB Hits:
pdb2PTH Peptidyl-Trna Hydrolase From Escherichia Coli 131 9e-032
pdb2PTH Peptidyl-Trna Hydrolase From Escherichia Coli 293 8e-081

Gene Protein Sequence:
MTKLIVGLGNPGSKYHETKHNVGFMALDRIVKPLNVQFTENKTFKAETVA
TFINGEKIYFIKPTTFMNASGLAVRAFLAYYNLTVEDLIVIYDDLDMEVG
KIRFRQKGSAGGHNGIKSIIKEIGTQEFDRIKIGIGRPKDKMTVVNYVLG
KFDKKDEITIFNTLDKVDKAVNYYLQTKNFEQTMQKFNG

Gene Nucleotide Sequence:  Sequence Viewer
ATGACTAAATTAATTGTTGGCCTTGGAAATCCAGGCAGTAAATATCATGA
AACGAAACATAATGTTGGCTTTATGGCTCTTGACAGAATTGTCAAGCCTT
TGAATGTTCAGTTTACAGAAAATAAAACATTTAAAGCAGAAACAGTAGCG
ACTTTTATTAATGGTGAAAAAATTTATTTTATTAAACCAACTACATTTAT
GAATGCCAGTGGTTTAGCTGTCAGAGCTTTTCTAGCTTATTATAATTTAA
CTGTGGAAGATCTAATTGTTATTTATGATGATCTTGATATGGAAGTAGGA
AAAATACGTTTTCGTCAAAAAGGCTCTGCTGGTGGACATAATGGTATAAA
AAGCATTATCAAGGAAATTGGGACTCAGGAATTTGATCGTATCAAGATTG
GTATTGGCCGTCCAAAGGATAAGATGACAGTCGTTAACTATGTTTTAGGA
AAATTTGATAAAAAAGATGAAATAACTATTTTTAACACACTTGATAAAGT
TGACAAAGCTGTCAATTACTATTTACAAACGAAAAATTTTGAACAAACAA
TGCAAAAATTTAATGGGTAA

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