Use of Model Systems

The proposed research may include model systems, including animal models. However, at some point during the grant period, the proposed research must include work on human cancer. Work developing or refining model systems will be supported only if the proposed research objectives actively test the relevance of the model to human cancer.

Data Sharing

Under the NIH Data Sharing Policy, grantees are expected to engage in a timely release of final data sets that have been generated with NIH support for use by other researchers, provide a Data Sharing Plan that will achieve this objective, OR state why data sharing is not possible or appropriate. No Data Sharing Plan is required for the mentored phase of the K99 mechanism because it supports career development. However, during the un-mentored, independent phase of the grant (R00 award), grantees are responsible to share the data and provide an acceptable Data Sharing Plan to the NIH as part of their NIH grant support.

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