Testing Status of Agents at NTP
2,4-Diaminophenol dihydrochloride
CASRN: 137-09-7
Related: 2,4-DIAMINOPHENOL HYDROCHLORIDE 29849-01-2
Formula: C6-H8-N2-O.2CL-H
Synonyms/Common Names:
- DIANOL
Known Uses:
PHOTOGRAPHIC DEVELOPER. DYEING FURS AND HAIR. ANALYTICAL REAGENT. (TDB)
Short-Term Toxicity
- 14-Day (Gavage)
(C60026) Completed
- NTIS No. PB93-117919
(Peer Review 03/11/1991)
Citation: NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CAS NO. 137-09-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB93-117919
(Peer Review 03/11/1991)
- 13-Week (Gavage)
(C60026) Completed
- NTIS No. PB93-117919
(Peer Review 03/11/1991)
Citation: NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CAS NO. 137-09-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,.012,.200, M: 0,.005,.075 G/KG/10 PER GROUP
- NTIS No. PB93-117919
(Peer Review 03/11/1991)
Long-Term Carcinogenicity
- 2-YEAR (Gavage)
(C60026) Report Complete
- TR-401 (NTIS No. PB93-117919)
(Peer Review 03/11/1991)
NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CAS NO. 137-09-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats No Evidence
- Female Rats No Evidence
- Male Mice Some Evidence
- Female Mice No Evidence
- Dose: R: 0,12.5,25, M: 0,19,38 MG/KG/60 PER GROUP
- TR-401 (NTIS No. PB93-117919)
(Peer Review 03/11/1991)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(729737) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Negative
- Sister Chromatid Exchange Negative
- Drosophila
(431842) Completed
- Citation: Zimmering, S., Mason, J.M., Valencia, R., and Woodruff, R.C. Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 87-100
- Reciprocal Translocation/Sex-Linked Recessive Lethal Inconclusive
- Mouse Lymphoma
(299952) Completed
- Citation: McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I. Results for nine compounds. Environ. Mutagen. Vol. 9 (1987) 143-160
- Positive
- Salmonella
(539410) Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Positive
Web page last updated on November 24, 2008