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- New NIMH Research Strives to Understand How Antidepressants May Be Associated with Suicidal Thoughts and Actions
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November 13, 2006
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Science Update
The National Institute of Mental Health (NIMH), part of the National Institutes of Health, is funding five new research projects that will shed light on antidepressant medications, notably selective serotonin reuptake inhibitors (SSRIs), and their association with suicidal thoughts and actions.
- Odds of Beating Depression Diminish as Additional Treatment Strategies are Needed
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November 1, 2006
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Science Update
An overall assessment of the nation's largest real-world study of treatment-resistant depression suggests that a patient with persistent depression can get well after trying several treatment strategies, but his or her odds of beating the depression diminish as additional treatment strategies are needed.
- Antipsychotic Medications Used to Treat Alzheimer’s Patients Found Lacking
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October 11, 2006
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Press Release
Commonly prescribed antipsychotic medications used to treat Alzheimer’s patients with delusions, aggression, hallucinations, and other similar symptoms can benefit some patients, but they appear to be no more effective than a placebo when adverse side effects are considered, according to the first phase of a large-scale clinical trial funded by NIMH.
- New Schizophrenia Trial: Does Method of Administering Medication Make a Difference?
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September 5, 2006
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Science Update
A new clinical trial is testing whether an injection of a long-lasting antipsychotic medication every two weeks results in better adherence to treatment and better outcomes among people with schizophrenia than do oral medications taken daily.
- Subsequent Treatment Strategies for Persistent Depression Yield Modest Results
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September 1, 2006
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Science Update
Patients with treatment-resistant depression had a modest chance of becoming symptom-free when they tried different treatment strategies after two or three failed treatments, according to results from the nation's largest real-world study of depression.
- Brain Changes Mirror Symptoms in ADHD
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July 19, 2006
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Science Update
The severity of attention deficit hyperactivity disorder (ADHD) symptoms in youth appears to be reflected in their brain structure, recent NIMH-supported brain imaging studies are finding.
- New Factors Identified for Predicting Violence in Schizophrenia
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July 18, 2006
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Science Update
A study of adults with schizophrenia showed that symptoms of losing contact with reality, such as delusions and hallucinations, increased the odds of serious violence nearly threefold.
- Targeted Therapy Halves Suicide Attempts in Borderline Personality Disorder
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July 3, 2006
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Science Update
Dialectical Behavior Therapy (DBT) reduced suicide attempts by half compared with other types of psychotherapy available in the community in patients with borderline personality disorder, an NIMH-funded study has found.
- Switching to a Third Antidepressant Medication May Prove Helpful to Some with Treatment-Resistant Depression
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July 1, 2006
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Science Update
The next wave of results from the nation's largest real-world study of treatment-resistant depressionshows that patients had a moderate chance of becoming symptom-free when they switched
to a third antidepressant medication, following two previously unsuccessful medication attempts.
- Antidepressant Does Not Reduce Risk Of Relapse Among Patients With Anorexia Nervosa
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June 14, 2006
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Science Update
An NIMH-funded study has concluded that the antidepressant medication fluoxetine (Prozac) is no more effective than placebo in preventing relapse among patients with anorexia nervosa who had achieved a healthy weight during inpatient or day-program treatment.
