Ethylbenzene |
Gaseous ethylbenzene is heavier than air, and children generally spend more time on the floor or ground than do adults. Whether children would be different from adults in their weight-adjusted intake of ethylbenzene is currently unknown; |
Toluene |
Gaseous toluene is heavier than air, and because young children are closer to the ground or floor because of their height, they can breathe more toluene than adults during accidental exposures. Older children and adolescents could be exposed to toluene if they breathe household products containing toluene to obtain a so-called "high;" |
Xylene |
Xylene exposure symptoms for children are expected to be similar to those for adults. Ingestion of aspirin is likely to speed up the adverse effects of xylene in both the expectant mother and the fetus; |
TMB |
Too little is known about TMB (trimethylbenzene) to determine whether children are any more susceptible to exposure than are adults. |
For children who lived on the site, exposure to these chemicals could have occurred by exposure to airborne contaminants and dust during excavation activities. However, since air monitoring was not conducted during excavation and removal activities, it is not known if any of these contaminants were present at levels that could have caused adverse health effects. Air monitoring after the excavation and removal activities were completed did not indicate these contaminants were present at levels where adverse health effects could have been likely.
Ethylbenzene |
Ethylbenzene exposure of individuals with impaired pulmonary function has been shown to worsen symptoms. Individuals with liver or kidney disease might be more susceptible to ethylbenzene toxicity, as would persons taking medications or other drugs that are known hepatoxins. Persons with dermatitis or other skin diseases could be at greater risk because ethylbenzene is a defatting agent that could aggravate these symptoms. |
Toluene |
Toluene metabolism can be affected by environmental and genetic factors. Chronic consumers of alcohol or people taking medications that interfere with toluene metabolism could be more susceptible. Ethnic variations in enzyme efficiency are known to exist. Individuals with pre-existing defects in heart rhythm, asthma, or other respiratory difficulty might be at an increased risk from toluene exposure. |
Xylene |
Xylene exposure of individuals with subclinical and clinical epilepsy, renal, hepatic, or cardiac disease could be more susceptible to the effects of xylene. People with respiratory diseases, such as asthma, could potentially be at risk after inhalation exposure. The bioavailability of dermally absorbed xylene adsorbed to clay soils is greater than the bioavailability of dermally absorbed pure xylene. For females, toxicokinetic studies have shown that the bioavailability of xylene absorbed to soil is greater than when xylene is ingested alone. |
TMB |
Little dose/response information exists regarding TMB (trimethylbenzene). For the purpose of this public health assessment, it is assumed that persons with compromised respiratory, renal, hepatic, and cardiac systems will be more susceptible to TMB exposure than those in the general population. |
Because air monitoring was not conducted during excavation and removal activities, it is not known if any of these contaminants were present at levels where adverse health effects may have been likely. Air monitoring after the excavation and removal activities were complete did not indicate these contaminants were present at levels where adverse health effects could have been likely.