New York University School of Medicine
Department of Environmental Medicine
SLF 254B
57 Old Forge Road
Tuxedo, NY 10987
Phone: 845-731-3548
Fax: 845-351-5472
Email:
New York University School of Medicine: Mechanisms of Resistance of Aquatic Vertebrate Populations to Mixtures of Aromatic Hydrocarbons and Metal Contaminants
Publications
2006
Roy, Nirmal K., Simon C. Courtenay, R. Christopher Chambers, and Isaac I. Wirgin. 2006. Characterization of the aryl hydrocarbon receptor repressor and a comparison of its expression in Atlantic tomcod from resistant and sensitive populations. Environmental Toxicology and Chemistry. (http://etc.allenpress.com/entconline/?request =index-html) 25(2):560-571.
Wirgin, Isaac I., J.S. Weis, and Anne E. McElroy. 2006. Physiological and genetic aspects of toxicity in Hudson River species. Chapter 30 in: The Hudson River Estuary. Cambridge University Press, New York, NY. pp.441-464.
Yuan, Zhanpeng, Simon C. Courtenay, and Isaac I. Wirgin. 2006. Comparison of hepatic and extra hepatic induction of cytochrome P4501A by graded doses of aryl hydrocarbon receptor agonists in Atlantic tomcod from two populations. Aquatic Toxicology. (http://www.sciencedirect.com/science/journal/ 0166445X) 76(3-4):306-320.
Yuan, Zhanpeng, Simon C. Courtenay, R. Christopher Chambers, and Isaac I. Wirgin. 2006. Evidence of spatially extensive resistance to PCBs in an anadromous fish of the Hudson River. Environmental Health Perspectives. 114(1):77-84.
2005
Roy, Nirmal K. and Isaac I. Wirgin. 2005. Characterization of the aryl hydrocarbon receptor repressor and a comparison of its expression in Atlantic tomcod from resistant and sensitive populations. Environmental Toxicology and Chemistry. (http://etc.allenpress.com/entconline/?request =index-html) 25(2):560-571.
Sorrentino, Claudio, Nirmal K. Roy, Simon C. Courtenay, and Isaac I. Wirgin. 2005. Co-exposure to metals modulates CYP1A1 mRNA inducibility in Atlantic tomcod Microgadus tomcod from two populations. Aquatic Toxicology. (http://www.sciencedirect.com/science/journal/ 0166445X) 75(3):238-252.
Wirgin, Isaac I. and R. Christopher Chambers. 2005. Atlantic tomcod (Microgadus tomcod): A model species for the response of Hudson River fish to toxicants. In: Hudson River Fishes and their Environment. (John R. Waldman, K.E. Limburg, and D. Strayer, eds). Amer. Fish. Soc,
Wirgin, Isaac I., Cheryl Grunwald, Erik Carlson, Joseph Stabile, Douglas L. Peterson, and John R. Waldman. 2005. Range-wide population structure of shortnose sturgeon Acipenser brevirostrum based on sequence analysis of the mitochondrial DNA control region. Estuaries. (http://estuaries.olemiss.edu/) 28(3):406-421.
2004
Couillard, Catherine M., Isaac I. Wirgin, Michel Lebeuf, and Benoit Legare. 2004. Reduction of cytochrome P4501A with age in Atlantic tomcod from the St. Lawrence Estuary, Canada: relationship with emaciation and possible effect of contamination. Aquatic Toxicology. (http://www.sciencedirect.com/science/journal/ 0166445X) 68(3):233-247.
Fernandez, Marc P., Michael G. Ikonomou, Simon C. Courtenay, and Isaac I. Wirgin. 2004. Spatial variation in hepatic levels and patterns of PCBs and PCDD/Fs among young-of-the-year and adult Atlantic tomcod (Microgadus tomcod) in the Hudson River estuary. Environmental Science and Technology. (http://pubs.acs.org/journals/esthag/) 38(4):976-983.
Sorrentino, Claudio, Nirmal K. Roy, R. Christopher Chambers, Simon C. Courtenay, and Isaac I. Wirgin. 2004. B[a]P-DNA binding in early life-stages of Atlantic tomcod: population differences and chromium modulation. Marine Environmental Research. (http://www.sciencedirect.com/science/journal/ 01411136) 58(2-5):383-388.
Wirgin, Isaac I. and John R. Waldman. 2004. Resistance to contaminants in North American fish populations. Mutation Research. (http://www.elsevier.com/wps/find/journaldescr iption.cws_home/522820/description#descriptio n) 552(1-2):73-100.
2002
Roy, Nirmal K., Simon C. Courtenay, Grace Maxwell, Zhanpeng Yuan, R. Christopher Chambers, and Isaac I. Wirgin. 2002. Cytochrome P4501A1 is induced by PCB 77 and benzo[a]pyrene treatment but not by exposure to the Hudson River environment in Atlantic tomcod (Microgadus tomcod) post-yolk sac larvae. Biomarkers. (http://tandf.catchword.com/titles/1354750x.ht m) 7(2):162-173.
2001
Roy, Nirmal K., Simon C. Courtenay, Zhanpeng Yuan, M. Ikonomou, and Isaac I. Wirgin. 2001. An evaluation of the etiology of reduced CYP1A1 messenger RNA expression in the Atlantic tomcod from the Hudson River, New York, USA, using reverse transcriptase polymerase chain reaction analysis. Environmental Toxicology and Chemistry. (http://etc.allenpress.com/entconline/?request =index-html) 20:1022-1030.
Walsh, M.G., M.B. Bain, T. Squiers, John R. Waldman, and Isaac I. Wirgin. 2001. Morphological and genetic variation among shortnose sturgeon Acipenser brevirostrum from adjacent and distant rivers. Estuaries. (http://estuaries.olemiss.edu/) 24:41-48.
Wirgin, Isaac I., T. Oppermann, and Joseph Stabile. 2001. Genetic divergence of robust redhorse Moxostoma robustum (Cypriniformes Catostomidae) from the Oconee River and the Savannah River based on mitochondrial DNA control region sequences. Copeia. 526-530.
Yuan, Zhanpeng, Michael Wirgin, Simon C. Courtenay, Michael G. Ikonomou, and Isaac I. Wirgin. 2001. Is hepatic cytochrome P4501A1 expression predictive of hepatic burdens of dioxins, furans, and PCBs in Atlantic tomcod from the Hudson River estuary?. Aquatic Toxicology. (http://www.sciencedirect.com/science/journal/ 0166445X) 54(3-4):217-230.
25(2):560-571. 
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