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Person Details

Superfund Basic Research Program

Nancy D. Denslow

University of Florida
P.O. Box 100156
Gainesvillle, FL 32610
Phone: 352-392-2243 x5563
Fax: 352-392-4441
Email:

Projects

Research Briefs

Superfund Sites

Tower Chemical Co.

  • University of Florida: Molecular Mechanisms of Endocrine Disruption

Publications

2007
  • Barber, David S., A.J. McNally, Natalia Garcia-Reyero, and Nancy D. Denslow. 2007. Exposure to p,p'-DDE or dieldrin during the reproductive season alters hepatic CYP expression in largemouth bass (Micropterus salmoides). Aquatic Toxicology. (http://www.sciencedirect.com/science/journal/ 0166445X) Exit NIEHS Website 81(1):27-35.
2006
  • Cook, J., Nancy D. Denslow, T. Iguchi, Elwood Linney, A. Miracle, Joseph R. Shaw, Mark R. Viant, and Timothy R. Zacharewski. 2006. "Omics" approaches in the context of environment toxicology. (In: Emerging Molecular and Computational Approaches for Cross-Species Extrapolations). Chapter 1in: Society of Environmental Toxicology and Chemistry (SETAC) Annual Meeting 2006. Washington, DC. pp.1-29.
  • Garcia-Reyero, Natalia, David S. Barber, Timothy S. Gross, and Nancy D. Denslow. 2006. Modeling of gene expression pattern alteration by p,p'-DDE and dieldrin in largemouth bass. Marine Environmental Research. (http://www.sciencedirect.com/science/journal/ 01411136) Exit NIEHS Website S415-S419:62(supp.1).
2004
  • Blum, Jason L., Iris Knoebl, Patrick Larkin, Kevin J. Kroll, and Nancy D. Denslow. 2004. Use of suppressive subtractive hybridization and cDNA arrays to discover patterns of altered gene expression in the liver of dihydrotestosterone and 11-ketotestosterone exposed adult male largemouth bass (Micropterus salmoides). Marine Environmental Research. (http://www.sciencedirect.com/science/journal/ 01411136) Exit NIEHS Website 58(2-5):565-569.
2003
  • Denslow, Nancy D., Iris Knoebl, and Patrick Larkin. 2003. Approaches in proteomics and genomics for eco-toxicology. Chapter Vol. 6 in: Biochemistry and Molecular Biology of Fishes-Environmental Toxicology. Elsevier, Amsterdam, Netherlands.
  • Larkin, Patrick, Leroy C. Folmar, Michael J. Hemmer, Arianna J. Poston, and Nancy D. Denslow. 2003. Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray. EHP(Environmental Health Perspectives) ToxicoGenomics. 111(1T):29-36.
  • Larkin, Patrick, Iris Knoebl, and Nancy D. Denslow. 2003. Differential gene expression analysis in fish exposed to endocrine disrupting compounds. Comparative Biochemistry and Physiology, Part B: Biochemistry and Molecular Biology. (http://www.elsevier.com/locate/cbpb) Exit NIEHS Website 136(2):149-161.
  • Larkin, Patrick, Tara L. Sabo-Attwood, J. Kelso, and Nancy D. Denslow. 2003. Analysis of gene expression patterns in largemouth bass throughout their reproductive cycle and with exposure to p, p ' DDE using gene arrays. Ecotoxicology. 72(1):738Suppl.S.
  • Larkin, Patrick, Tara L. Sabo-Attwood, J. Kelso, and Nancy D. Denslow. 2003. Analysis of gene expression profiles in largemouth bass exposed to 17-beta-estradiol and to anthropogenic contaminants that behave as estrogens. Ecotoxicology. 12(6):463-468.
  • Sabo-Attwood, Tara L. and Nancy D. Denslow. 2003. Estrogen Receptor Alpha, but not Beta or Gamma Expression is induced by Estradiol and Xenoestrogens in Largemouth Bass (Micropterus salmoides) liver Tissue. In: Society of Toxicology, 42nd Annual Meeting, March. Salt Lake City, UT.
  • Sepulveda, Maria S., Brian P. Quinn, Nancy D. Denslow, Stewart E. Holm, and Timothy S. Gross. 2003. Effects of paper mill effluents on reproductive success of largemouth bass. Environmental Toxicology and Chemistry. (http://etc.allenpress.com/entconline/?request =index-html) Exit NIEHS Website 22(1):205-213.
2002
  • Bowman, Christopher J., Kevin J. Kroll, Timothy S. Gross, and Nancy D. Denslow. 2002. Estradiol-Induced Gene Expression in Largemouth Bass (Micropterus salmoides). Molecular and Cellular Endocrinology. (http://www.sciencedirect.com/science/journal/ 03037207) Exit NIEHS Website 196(1-2):67-77.
  • Gross, Timothy S., Maria S. Sepulveda, Carla M. Wieser, Jon J. Wiebe, Trenton R. Schoeb, and Nancy D. Denslow. 2002. Characterization of annual reproductive cycles for pond-reared Florida largemouth bass (Micropterus salmoides floridanus). American Fisheries Society Symposium. 31:205-212.
  • Gross, Timothy S., Maria S. Sepulveda, Carla M. Wieser, Jon J. Wiebe, Trenton R. Schoeb, Nancy D. Denslow, and William E. Johnson. 2002. Seasonal reproductive cycles for Florida largemouth bass. Black Bass. 31:205-215.
  • Kocerha, Rebecca Jannet, Tara L. Sabo-Attwood, J.J. Upp, M.S. Nelson, and Nancy D. Denslow. 2002. The regulation of the steroidogenic acute regulatory protein (Star Protein) in largemouth bass (Micropterus salmoides). In: Proceedings of the 41st Annual Meeting of the Society of Toxicology (SOT), March 17-21, 2002. Nashville, TN.
  • Larkin, Patrick, Leroy C. Folmar, Michael J. Hemmer, Arianna J. Poston, H. Stephen Lee, and Nancy D. Denslow. 2002. Array Technology as a tool to monitor exposure of fish to xenoestrogens. Marine Environmental Research. (http://www.sciencedirect.com/science/journal/ 01411136) Exit NIEHS Website 54(3-5):395-399.
  • Larkin, Patrick, Tara L. Sabo-Attwood, J. Kelso, and Nancy D. Denslow. 2002. Expression profiling of largemouth bass (Micropterus salmoides) exposed to estradiol, nonylphenol, and p,p'-DDE. In: Proceedings of the Society of Environmental Toxicology and Chemistry (SETC), 23rd Annual Meeting, Salt Lake City, Utah. November 16 - 20.
  • Larkin, Patrick, Tara L. Sabo-Attwood, J. Kelso, and Nancy D. Denslow. 2002. Gene expression analysis of largemouth bass exposed to estradiol, nonylphenol, and p,p'-DDE. Comparative Biochemistry and Physiology, Part B: Biochemistry and Molecular Biology. (http://www.elsevier.com/locate/cbpb) Exit NIEHS Website 133(4):543-557.
  • Sabo-Attwood, Tara L., Patrick Larkin, J. Kelso, and Nancy D. Denslow. 2002. Changes in largemouth bass gene expression following acute exposure to nonylphenol. In: Proceedings of the Society of Toxicology and Chemistry, November. Salt Lake City, UT.
  • Sabo-Attwood, Tara L., Patrick Larkin, J. Kelso, and Nancy D. Denslow. 2002. Gene Expression Profiles of Largemouth Bass Exposed to Nonylphenol and ICI 182,780. In: Proceedings of the International Congress on the Biology of Fish, July 21-26. Vancouver, Canada.
  • Sabo-Attwood, Tara L., M.S. Nelson, J.J. Upp, and Nancy D. Denslow. 2002. Differential expression of three estrogen receptor isotypes during largemouth bass (micropterus salmoides) reproduction and following exposure to nonylphenol. In: Proceedings of the 41st Annual Meeting of the Society of Toxicology (SOT), March 17-21, 2002. Nashville, TN.
  • Sepulveda, Maria S., William E. Johnson, John C. Higman, Nancy D. Denslow, Trenton R. Schoeb, and Timothy S. Gross. 2002. An evaluation of biomarkers of reproductive function and potential contaimant effects in Florida largemouth bass (Micropterus salmoides floridanus) sampled from the St. Johns River. Science of the Total Environment. (http://www.elsevier.com/wps/find/journaldescr iption.cws_home/503360/description#descriptio n) Exit NIEHS Website 289(1-3):133-144.
2001
  • Denslow, Nancy D., Christopher J. Bowman, R.J. Ferguson, H. Stephen Lee, Michael J. Hemmer, and Leroy C. Folmar. 2001. Induction of Gene Expression in Sheepshead minnows (Cyprinodon Varigatus) Treated with 17-p-estradiol, Diethylstilbestrol or Ethinylestradiol: The Use af mRNA Fingerprint as an Indicator of Gene Regulation. General and Comparative Endocrinology. 121:250-260.
  • Sepulveda, Maria S., David S. Ruessler, Nancy D. Denslow, Stewart E. Holm, Trenton R. Schoeb, and Timothy S. Gross. 2001. Assessment of reproductive effects in largemouth bass (Mircopterus salmoides) exposed to bleached/unbleached kraft mill effluents. Archives of Environmental Contamination and Toxicology. (http://link.springer.de/link/service/journals /00244/tocs.html) Exit NIEHS Website 41(4):475-482.
2000
  • Bowman, Christopher J., Kevin J. Kroll, Leroy C. Folmar, M.J. Heurne, and Nancy D. Denslow. 2000. Vitellogenin transcriptional activation in sheepshead minnow following acute estrogen exposure in vivo. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) Exit NIEHS Website 54:326.
  • Bowman, Christopher J., Kevin J. Kroll, Michael J. Hemmer, Leroy C. Folmar, and Nancy D. Denslow. 2000. Estrogen-induced vitellogenin mRNA and protein in sheepshead minnow (Cyprinodon variegatus). General and Comparative Endocrinology. 120(3):300-313.
  • Denslow, Nancy D., V. Saunders, Marjorie M. Chow, Timothy S. Gross, Maria S. Sepulveda, and Stewart E. Holm. 2000. The estrogen mimicking potential of effluent from CEHD type paper mill in central Florida. In: Proceedings of the 4th International Conference on Environmental Impacts of the Pulp and Paper Industry, 12-15 June. Helsinki, Finland. pp.227-231.
  • Holm, Stewart E., Maria S. Sepulveda, Brian P. Quinn, Joseph J. Delfino, Carla M. Wieser, Nancy D. Denslow, and Timothy S. Gross. 2000. Endocrine Disruption in Largemouth Bass and Exposure to Papermill Effluents: A Reconnaissance Study of the Lower St. Johns River Basin. In: Proceedings of the International Conference: Pulp and papermill research. Helsinki, Finland.
  • McDonald, K.K., C.J. Schmitt, T. Bartish, Christine Bunck, G.M. Dethloff, V.S. Blazer, Nancy D. Denslow, and Timothy S. Gross. 2000. Evaluation of Reproductive Biomarkers and Potential Endocrine Disruption for Fish in the Mississippi River Basin. In: Proceedings of the 21st Annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), November 12-16, 2000. Nashville, TN.
  • Sabo-Attwood, Tara L., Christopher J. Bowman, and Nancy D. Denslow. 2000. Molecular Cloning of Estrogen Receptor Isotypes in Largemouth Bass, Micropterus Salmoides. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) Exit NIEHS Website 54:263.
  • Sepulveda, Maria S., David S. Ruessler, Nancy D. Denslow, Stewart E. Holm, and Timothy S. Gross. 2000. Effects of Paper Mill Effluents on the Reproductive Success of Florida Largemouth Bass. In: Proceedings of the 4th International Conference on Environmental Impacts of the Pulp and Paper Industry, 12-15 June. Helsinki, Finland.
1999
  • Bowman, Christopher J. and Nancy D. Denslow. 1999. Development and validation of a species- and gene-specific molecular biomarker: Vitellogenin mRNA in largemouth bass (Micropterus salmoides). Ecotoxicology. 8:399-416.
  • Denslow, Nancy D., Marjorie M. Chow, Kevin J. Kroll, and Linda Green. 1999. Vitellogenin as a Biomarker of Exposure to Estrogen or Estrogen Mimics. Ecotoxicology. 8:385-398.
1998
  • Ankley, Gerald T., Ellen Mahaich, Ralph Stahl, Donald E. Tillitt, Theo Colborn, Susan McMaster, Ron Miller, John Bantle, Pamela Campbell, Nancy D. Denslow, Richard L. Dickerson, Leroy C. Folmar, Michael Fry, John P. Giesy, L. Earl Gray, Patrick D. Guiney, Thomas Hutchinson, Sean P. Kennedy, Vincent J. Kramer, Gerald LeBlank, Monte Mayes, Alison Nimrod, Reynaldo Patino, Richard Peterson, Richard Purdy, Robert Ringer, Peter Thomas, Les Touart, Glen Van Der Kraak, and Timothy R. Zacharewski. 1998. Overview of a workshop on screening methods for detecting potential (anti-) estrogenic/androgenic chemicals in wildlife. Environmental Toxicology and Chemistry. (http://etc.allenpress.com/entconline/?request =index-html) Exit NIEHS Website 17(1):68-87.
  • Chow, Marjorie M., Kevin J. Kroll, L. Sapp, L. Shutt, A. Lorenzen, S. Deem, Timothy S. Gross, and Nancy D. Denslow. 1998. Monoclonal Antibodies that Cross React with Vitellogenins from Quail, Terns and Barn Swallows. In: Proceedings of the Society of Environmental Toxicology and Chemistry (SETC) 19th Annual Meeting. Charlotte, NC.
  • Denslow, Nancy D., Steven L. Goodbred, Hugh E. Bevans, and Timothy S. Gross. 1998. Exposure of Fish to Estrogenic Xenobiotics in Rivers and Lakes in the United States. In: Proceedings of the Japan Conference on Environmental Hormones. Kyoto, Japan.
  • Denslow, Nancy D., Kevin J. Kroll, Trenton R. Schoeb, B. Johnson, Jon J. Wiebe, Carla M. Wieser, and Timothy S. Gross. 1998. Documentation of endocrine-disruption and altered seasonal reproductive parameters for brown-bullhead catfish from several lakes in Central Florida. In: Proceedings of the Society of Environmental Toxicology and Chemistry (SETC) 19th Annual Meeting. Charlotte, NC.
  • Douglas, David R., William E. Johnson, Nancy D. Denslow, Carla M. Wieser, Jon J. Wiebe, and Timothy S. Gross. 1998. Endocrine Disruption in Largemouth Bass in a Re-flooded Agricultural Area. In: Proceedings of the Society of Environmental Toxicology and Chemistry (SETC) 19th Annual Meeting. Charlotte, NC.
  • Sepulveda, Maria S., Evan P. Gallagher, Trenton R. Schoeb, Nancy D. Denslow, Stewart E. Holm, Denis A. Gross, S. Ruessler, and Timothy S. Gross. 1998. Effects of Paper Mill Effluents on Reproduction and Health of Largemouth Bass (Micropterus salmoides) in Florida. In: Proceedings of the Society of Environmental Toxicology and Chemistry (SETC) 19th Annual Meeting. Charlotte, NC.
1996
  • Bevans, Hugh E., Steven L. Goodbred, J.F. Miesner, S.A. Watkins, Timothy S. Gross, Nancy D. Denslow, and Trenton R. Schoeb. 1996. Synthetic organic compounds and carp endocrinology and histology in Las Vegas Wash and Las Vegas and Callville Bays of Lake Mead, Nevada. In: U.S. Department of the Interior - U.S. Geological Survey: Water Resources Investigations Report 96-4266.
  • Goodbred, Steven L., Robert J. Gilliom, Timothy S. Gross, Nancy D. Denslow, Wade L. Bryant, and Trenton R. Schoeb. 1996. Reconnaissance of 17β-estradiol, 11-ketotestosterone and vitellogenin in common carp of United States streams and the potential contaminant effects on their endocrine system. U.S. Geological Survey, Open File Report.
  • Gross, Timothy S., Jon J. Wiebe, Carla M. Wieser, Suresh Shrestha, Nancy D. Denslow, and William E. Johnson. 1996. Documentation of endocrine-disruption and altered seasonal reproductive parameters for large-mouth bass from several lakes in Central Florida. In: Society of Environmental Toxicology and Chemistry (SETAC) Annual Meeting 1996. Washington, DC.
1995
  • Denslow, Nancy D., Marjorie M. Chow, N. Chow, C.C. Folmar, and Craig V. Sullivan. 1995. Development of a Quantitative Assay for Vitellogenin to Monitor Estrogen-like Environmental Contaminants. In: Proceedings of the Second SETAC (Society of Environmental Toxicology and Chemistry) World Congress. Vancouver, British Columbia, Canada.
  • Denslow, Nancy D., Linda Green, Marjorie M. Chow, Scott A. Heppell, C.C. Folmar, and Craig V. Sullivan. 1995. Characterization of a Library of Monoclonal Antibodies against Vitellogenin: Conservation of Epitopes. In: Proceedings of the Second SETAC (Society of Environmental Toxicology and Chemistry) World Congress. Vancouver, British Columbia, Canada.
  • Folmar, Leroy C., Nancy D. Denslow, R.A. Wallace, G. LaFleur, R.S. Gross, Bonomelli, and Craig V. Sullivan. 1995. A Highly Conserved N-terminal Sequence for Teleost Vitellogenin with Potential Value to the Biochemistry, Molecular Biology and Pathology of Vitellogenesis. Journal of Fish Biology. (http://www.blackwellpublishing.com/journal.as p?ref=0022-1112&site=1) Exit NIEHS Website 46(2):255-263.
  • Heppell, Scott A., Nancy D. Denslow, Leroy C. Folmar, and Craig V. Sullivan. 1995. Universal Assay of Vitellogenin as a Biomarker for Environmental Estrogens. Environmental Health Perspectives. 103(Suppl.7):9-15.
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Last Reviewed: 19 May 2008