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PART 2. CASE DEFINITIONS1 FOR NON-NOTIFIABLE INFECTIOUS DISEASESGenital Herpes (Herpes Simplex Virus) (Revised 9/96) Clinical description A condition characterized by visible, painful genital or anal lesions Laboratory criteria for diagnosis
Case classification Probable: a clinically compatible case (in which primary and secondary syphilis have been excluded by appropriate serologic tests and darkfield microscopy, when available) with either a diagnosis of genital herpes based on clinical presentation (without laboratory confirmation) or a history of one or more previous episodes of similar genital lesions Confirmed: a clinically compatible case that is laboratory confirmed Comment Genital herpes should be reported only once per patient. The first diagnosis for a patient with no previous diagnosis should be reported. Genital Warts (Revised 9/96) Clinical description An infection characterized by the presence of visible, exophytic (raised) growths on the internal or external genitalia, perineum, or perianal region Laboratory criteria for diagnosis
Case classification Probable: a clinically compatible case without histopathologic diagnosis and without microscopic or serologic evidence that the growth is the result of secondary syphilis Confirmed: a clinically compatible case that is laboratory confirmed Comment Genital warts should be reported only once per patient. The first diagnosis for a patient with no previous diagnosis should be reported. Granuloma Inguinale Clinical description A slowly progressive ulcerative disease of the skin and lymphatics of the genital and perianal area caused by infection with Calymmatobacterium granulomatis. A clinically compatible case would have one or more painless or minimally painful granulomatous lesions in the anogenital area. Laboratory criteria for diagnosis
Case classification Confirmed: a clinically compatible case that is laboratory confirmed Lymphogranuloma Venereum Clinical description Infection with L1, L2, or, L3 serovars of Chlamydia trachomatis may result in a disease characterized by genital lesions, suppurative regional lymphadenopathy, or hemorrhagic proctitis. The infection is usually sexually transmitted. Laboratory criteria for diagnosis
Case classification Probable: a clinically compatible case with one or more tender fluctuant inguinal lymph nodes or characteristic proctogenital lesions with supportive laboratory findings of a single C. trachomatis complement fixation titer of 64 Confirmed: a clinically compatible case that is laboratory confirmed Mucopurulent Cervicitis (Revised 9/96) Clinical description Cervical inflammation that is not the result of infection with Neisseria gonorrhoeae or Trichomonas vaginalis. Cervical inflammation is defined by the presence of one of the following criteria:
Laboratory criteria for diagnosis
Case classification Confirmed: a clinically compatible case in a female who does not have either gonorrhea or trichomoniasis Comment Mucopurulent cervicitis (MPC) is a clinical diagnosis of exclusion. The syndrome may result from infection with any of several agents (see Chlamydia trachomatis, Genital Infections). If gonorrhea, trichomoniasis, and chlamydia are excluded, a clinically compatible illness should be classified as MPC. An illness in a female that meets the case definition of MPC and C. trachomatis infection should be classified as chlamydia. Nongonococcal Urethritis (Revised 9/96) Clinical description Urethral inflammation that is not the result of infection with Neisseria gonorrhoeae. Urethral inflammation may be diagnosed by the presence of one of the following criteria:
Laboratory criteria for diagnosis
Case classification Confirmed: a clinically compatible case in a male in whom gonorrhea is not found, either by culture, Gram stain, or antigen or nucleic acid detection Comment Nongonococcal urethritis (NGU) is a clinical diagnosis of exclusion. The syndrome may result from infection with any of several agents (see Chlamydia trachomatis, Genital Infection). If gonor-rhea and chlamydia are excluded, a clinically compatible illness should be classified as NGU. An illness in a male that meets the case definition of NGU and C. trachomatis infection should be classified as chlamydia. Pelvic Inflammatory Disease (Revised 9/96) Clinical case definition A clinical syndrome resulting from the ascending spread of microorganisms from the vagina and endocervix to the endometrium, fallopian tubes, and/or contiguous structures. In a female who has lower abdominal pain and who has not been diagnosed as having an established cause other than pelvic inflammatory disease (PID) (e.g., ectopic pregnancy, acute appendicitis, and functional pain), all the following clinical criteria must be present:
In addition to the preceding criteria, at least one of the following findings must also be present:
Case classification Confirmed: a case that meets the clinical case definition Comment For reporting purposes, a clinician's report of PID should be counted as a case. 1 Centers for Disease Control and Prevention. Case definitions for infectious conditions under public health surveillance, 1997. MMWR 1997;46(No. RR-10;1).
Page last modified: December 13, 2006 Page last reviewed: December 13, 2006 Historical Document Content Source: Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention |
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