TMS-MRI

Dr. Elisabeth Caparelli, an MRI physicist researcher at Brookhaven, has developed a novel multi-component methodology integrating Transcranial Magnetic Stimulation (TMS) and interleaved acquisition of functional MRI (fMRI), using BNL’s 4T MR scanner, so as to supply the unique windows on brain functional connectivity. TMS is used to stimulate a specific brain area and the associated activated network is assessed with fMRI. The novel combination of simultaneous TMS&fMRI at a high magnetic field will allow us to answer fundamental questions about the functional activity patterns directly associated with a specific brain region.

The Brookhaven TMS research program aims to establish an innovative multimodality TECHNOLOGY by combining TMS, simultaneously or in separated sections, with other imaging modes, such as PET and fMRI, to advance our knowledge about brain MECHANISMS UNDERLYING behavior, the progression of neurological diseases, and the effects of drugs on neuronal activity; ultimately, this will assist in developing a new tool for UNDERSTANDING AND treating neuropsychiatric illnesses, such as drug addiction and depression. This unique complex neuroimaging combination will allow us to carry out cutting-edge research on fundamental questions related with brain behavior/cognitive function and, therefore, to conduct an outstandingly innovative and exploratory research, promoting advances IN TECHNOLOGY IN THE SERVICE OF medical sciences at BNL.



Top of Page

Last Modified: January 31, 2008