CTN Publications

Ding, Y.-S., Kil, K.-E., Lin, K.-S., Ma, W., Yokota, Y. and Carroll, I. F. A Novel Nicotinic Acetylcholine Receptor Antagonist Radioligand for PET Studies. Bioorgan. Med. Chem. Lett. 16, 1049-1053, 2006.

Marsteller, D. A., Barbarich-Marsteller, N. C., Fowler, J. S., Schiffer, W. K., Alexoff, D. L., Rubins, D. and Dewey, S. L. Reproducibility of Intraperitoneal 2-deoxy-2-[18F]-fluoro-D-glucose Cerebral Uptake in Rodents Through Time. Nucl. Med. Biol. 33, 71-79, 2006.

Schiffer, W. K., Volkow, N. D., Fowler, J. S., Alexoff, D. L., Logan, J. and Dewey, S. L.Therapeutic Doses of Amphetamine and Methylphenidate Differentially Increase Synaptic and Extracellular Dopamine. Synapse 59, 243-251, 2006.

Ferrieri, A. P., Thorpe, M. R., Ferrieri, R. A. Stimulating Natural Defenses in Populus Increases their Metabolism of Carbon Tetrachloride. Int J. Phytoremediation (in press)

2005

Babst, B., Ferrieri, R. A., Gray, D. W., Thorpe, M. R., Lerdau, M., Schlyer, D., Schueller, M., Orians, C. M. Jasmonic Acid Induces Rapid Changes in Carbon Transport and Partitioning in Populus. New Phytologist 167, 63-72, 2005.

Barbarich-Marsteller NC, Marsteller DA, Alexoff DL, Fowler JS, Dewey SL. MicroPET imaging in an animal model of anorexia nervosa. Synapse. 2005 Aug;57(2):85-90.

Benveniste H, Blackband S, Translational Neuroscience and MR microscopy.. 2006 Lancet Neurology (under final revision)

Benveniste H, Fowler JS, Rooney W, Ding YS, Baumann A, Moller D, Backus W, Logan J, Carter P, Coplan E, Biegon A, Rosenblum L, Scharf B, Gatley SJ, Volkow ND. Maternal and Fetal 11C-Cocaine Uptake and Kinetics Measured In Vivo by Combined PET and MRI in Pregnant Nonhuman Primates. J Nucl Med 2005;46,312-320

Benveniste, H., Fowler, J. S., Rooney, W., Ding, Y.-S., Baumann, A. L., Moller, D. H., Du, C., Backus, W., Logan, J., Carter, P., Coplan, J. D., Biegon, A., Rosenblum, L., Scharf, B., Gatley, S. J. and Volkow, N. D., Maternal and Fetal 11C-Cocaine Uptake and Kinetics Measured In Vivo by Combined PET and MRI in Pregnant Nonhuman Primates J. Nucl. Med. 46, 312-320, 2005.

Brodie, J. D., Figueroa, E., Laska, E. M. and Dewey, S. L., Safety and Efficacy of Gamma-vinyl GABA (GVG) for the Treatment of Methamphetamine and/or Cocaine Addiction. Synapse 55, 122-125, 2005.

Caparelli EC, Tomasi D, and Ernst T. “The Effect of Small Rotations on R2* with Echo Planar Imaging”. NeuroImage 24: 1164-1169 (2005).

Ding, Y.-S. and Fowler, J. S., New Generation Radiotracers for nAChR and NET Nucl. Med. Biol. 32, 707-718, 2005.

Du C, Koretsky AP, Izrailtyan I, Benveniste H. Simultaneous detection of blood volume, oxygenation, and intracellular calcium changes during cerebral ischemia and reperfusion in vivo using diffuse reflectance and fluorescence. J Cereb Blood Flow Metab. 2005 Aug;25(8):1078-92.

Ferrieri, R. A., Gray, D. W., Babst, B. A., Schueller, M. J., Schlyer, D. J., Thorpe, M. R., Orians, C. M., Lerdau, M. Use of Carbon-11 Shows that Exogenous Jasmonic Acid Influences Carbon Sources for Isoprene Biosynthesis in Populus. Plant Cell & Environment 28, 591-602, 2005.

Foerster B, Tomasi D, and Caparelli EC. “Magnetic Field Shift due to Mechanical Vibration in Functional MRI”. Magn Reson Med 54: 1261-1267 (2005).

Fowler JS, Logan J, Wang G-J, Volkow ND, Telang F, Zhu W, Franceschi D, Shea C, Garza V, Xu Y, Ding YS, Alexoff D, Warner D, Netusil N, Carter P, Jayne M, King P, Vaska P. Comparison of monoamine oxidase a in peripheral organs in nonsmokers and smokers. J Nucl Med. 46(9), 1414-1420 (2005). (DOE, NIH)

Fowler JS, Volkow ND, Logan J, Wang G-J. Translational Neuroimaging: PET Studies of Monoamine oxidase. Molecular Imaging & Biology 1-11 (2005). (DOE, NIH)

Gatley SJ, Volkow ND, Wang G-J, Fowler JS, Ding Y-S, Gerasimov M. PET Imaging in Drug Abuse Research. Current Pharmaceutical Design. 11, 3203-3219 (2005). (DOE, NIH)

Gerasimov, M. R., Ferrieri, R., Pareto, D., Logan, J., Alexoff, D. and Ding, Y.-S. Synthesis and Evaluation of Inhaled [11C]butane and Intravenously Injected [11C]acetone as Potential Radiotracers for Studying Inhalant Abuse. Nucl. Med. Biol. 32, 201-208, 2005.

Goldstein RZ, Alia-Klein N, Leskovjan AC, Fowler JS, Wang G-J, Gur RC, Hitzemann R, Volkow ND. Anger and depression in cocaine addiction: association with the orbitofrontal cortex. Psychiatry Res 138 (1), 13-22 (2005) (DOE, NIH)

Herth, M. M., Thorpe, M. R. and Ferrieri, R. A. Synthesis of the Phytohormone [11C]Methyl Jasmonate via Methylation on a C18 Sep PakTM Cartridge. J. Label Cmpds. Radiopharm. in 48(5), 379-386, 2005.

Lin, K.-S. and Ding, Y.-S. Synthesis and C-11 Labeling of Three Potent Norepinephrine Transporter Selective Ligands ((R)-Nisoxetine, Lortalamine and Oxaprotiine) for Comparative PET Studies in Baboons. Bioorgan. Med. Chem. 13, 4658-4666, 2005.

Lin, K.-S., Ding, Y.-S., Kim, S.-W. and Kil, K.-E. Synthesis, Enantiomeric Resolution and F-18 Labeling of Reboxetine Analogs: Promising Radioligands for Imaging the Norepinephrine Transporter with Positron Emission Tomography. Nucl. Med. Biol. 32, 415-422, 2005.

Logan, J. and Fowler, J. S. Evidence for Reduced Arterial Plasma Input, Prolonged Lung Retention and Reduced Lung Monoamine Oxidase in Smokers. Nucl. Med. Biol. 32, 521-529, 2005.

Logan, J., Ding, Y.-S., Lin, K.-S., Pareto, D., Fowler, J. S. and Biegon, A. Modeling and Analysis of PET Studies with Norepinephrine Transporter (NET) Ligands: The Search for a Reference Region. Nucl. Med. Biol. 32, 531-542, 2005.

Ma Y, Hof P, Grant S, Blackband S.J., Slatest L, Bennett R, Mcguigan M., Benveniste H. A three-dimensional digital atlas database of the adult C57BL/6J Mouse brain by Magnetic Resonance Microscopy Neuroscience. 2005;135(4):1203-15

Schiffer, W. K., Alexoff, D., Shea, C., Logan, J. and Dewey, S. L. Development of a Simultaneous PET/Microdialysis Method to Identify the Optimal Dose of 11C-Raclopride for Small Animal Imaging. J. Neurosci. Methods 144, 25-34, 2005.

Schiffer, W. K., Lee, D. E., Brodie, J. D. and Dewey, S. L. Imaging Addiction with PET: Is Insight in Sight? Drug Discovery Today 10, 547-562, 2005.

Thanos PK, Rivera SN, Weaver K, Grandy DK, Rubinstein M, Umegaki H, Wang G-J, Hitzemann R, Volkow ND. Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking. Life Sci. 77(2), 130-139 (2005). (DOE, NIH)

Tomasi D, and Caparelli EC. “Intra-vascular contamination in activation patterns of working memory”. J Cereb Blood Flow Metab (in press).

Tomasi D, and Ernst T. “A simple theory for vibration of MRI gradient coils”. Braz J Phys (in press).

Tomasi D, Caparelli EC, Chang L, and Ernst T. “fMRI-acoustic noise alters brain activation during working memory tasks”. NeuroImage 27: 377-386 (2005).

Tomasi D, Chang L, Caparelli EC, Telang F, and Ernst T. “The human inmmunodeficiency virus reduces network capacity: acoustic noise effect”. Ann Neurol 59:419-423 (2006).

Tomasi D, Ernst T, Caparelli EC, and Chang L. “Common deactivation patterns during working memory and visual attention tasks: An intra-subject fMRI study at 4 Tesla” Human Brain Mapp [Epub ahead of print].

Tomasi D. “Optimization of biplanar gradient coils for magnetic resonance imaging”. Braz J Phys (in press).

Tomasi D. Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy, by J. Gillard, A. Waldman, and P. Barker, 2005. Health Physics 89, 95-96, 2005.

Volkow ND, Wang G-J, Fowler JS, Ding YS. Imaging the effects of methylphenidate on brain dopamine: new model on its therapeutic actions for attention deficit/hyperactivity disorder”. Biol Psychiatry. 57(11), 1410-1415 (2005). (DOE, NIH)

Volkow ND, Wang G-J, Fowler JS, Goldstein R. Imaging the Addicted Brain. In: The Cellular Biology of Addiction. Cold Spring Harbor Press. (in press). (DOE, NIH)

Volkow ND, Wang G-J, Fowler JS, Learned-Coughlin S, Yang J, Logan J, Schlyer D, Gatley JS, Wong C, Zhu W, Pappas N, Schueller M, Jayne M, Carter P, Warner D, Ding YS, Shea C, Xu Y. The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects. Biological Psychiatry 57(6), 640-646 (2005). (DOE, NIH)

Volkow ND, Wang G-J, Franceschi D, Fowler JS, Thanos PK, Maynard L, Gatley SJ, Wong CT, Veech RL, Kunos G, Li TK. Low doses of alcohol substantially decrease glucose metabolism in the human brain. Neuroimage 29(1), 295-301 (2006). (DOE, NIH)

Volkow ND, Wang G-J, Ma Y, Fowler JS, Wong C, Ding YS, Hitzemann R, Swanson JM, Kalivas P. Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction. J Neurosci. 25(15), 3932-3939 (2005). (DOE, NIH)

Volkow, N. D., Wang, G. J., Fowler, J. S., Learned-Coughlin, S., Yang, J., Logan, J., Schlyer, D. J., Gatley, S. J., Wong, C., Zhu, W., Pappas, N., Schueller, M., Jayne, M., Carter, P., Warner, D., Ding, Y.-S., Shea, C. and Xu, Y. The Slow and Long-lasting Blockade of Dopamine Transporters in Human Brain Induced by the New Antidepressant Drug Radafaxine Predict Poor Reinforcing Effects. Biol. Psychiatry 15, 640-646, 2005.

Wang G-J, Thanos PK, Volkow ND. Small Animal PET Imaging for Drug Abuse Research. In: Proceeding for Animal Molecule Imaging Symposium (in press). (DOE, NIH)

Zhang L, Samaras D, Tomasi D, Alia-Klein N, Cottone LA, Leskovjan LC, Volkow ND, Goldstein RZ. Exploiting Temporal Information in Functional Magnetic Resonance Imaging Brain Data. Lecture Notes in Computer Science 3749: 679-687, 2005.

Zhang L, Samaras D, Tomasi D, Volkow ND, Goldstein RZ. “Machine Learning for Clinical Diagnosis from Functional Magnetic Resonance Imaging”. Computer Vision and Pattern Recognition, 2005. IEEE Computer Society Conference 1: 1211 – 1217 (2005).

2004

Du C., Pan Y. T., MacGowan G. A., Koretsky A. P.; " Decreasing motion artifacts in calcium-dependent fluorescence transients from the perfused mouse heart using frequency filtering ", Cell Calcium, 35, 141-153, (2004). Medline Abstract

Ding YS, Gatley SJ, Thanos PK, Shea C, Garza V, Xu Y, Carter P, King P, Warner D, Taintor NB, Park DJ, Pyatt B, Fowler JS, Volkow ND.
Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration.
Synapse. 2004 Sep 1;53(3):168-75. Medline Abstract

Ding YS, Fowler JS, Logan J, Wang GJ, Telang F, Garza V, Biegon A, Pareto D, Rooney W, Shea C, Alexoff D, Volkow ND, Vocci F.
6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: studies in the human brain and in vivo demonstration of specific binding in white matter.
Synapse. 2004 Sep 1;53(3):184-9. Medline Abstract

Fowler JS, Logan J, Wang G-J, Volkow ND, Telang F, Ding YS, Shea C, Garza V, Xu Y, Li Z, Alexoff D, Vaska P, Ferrieri R, Schlyer D, Zhu W and Gatley SJ
Comparison of the binding of the irreversible monoamine oxidase tracers [ 11 C]clorgyline and [ 11 C]L-deprenyl in brain and peripheral organs in humans.
Nucl Med Biol. 2004 Apr;31(3):313-9. Medline Abstract

Fowler JS, Volkow ND, Wang GJ, Ding YS.
2-deoxy-2-[18F]fluoro-D-glucose and alternative radiotracers for positron emission tomography imaging using the human brain as a model.
Semin Nucl Med. 2004 Apr;34(2):112-21. Medline Abstract

Goldstein RZ, Leskovjan AC, Hoff AL, Hitzemann R, Bashan F, Khalsa SS, Wang GJ, Fowler JS, Volkow ND
Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex.
Neuropsychologia. 2004;42(11):1447-58. Medline Abstract

Lee DE, Schiffer WK, Dewey SL.
Gamma-vinyl GABA (vigabatrin) blocks the expression of toluene-induced conditioned place preference (CPP).
Synapse. 2004 Dec 1;54(3):183-5. Medline Abstract

Lin KS, Ding YS
Synthesis, enantiomeric resolution, and selective C-11 methylation of a highly selective radioligand for imaging the norepinephrine transporter with positron emission tomography.
Chirality. 2004 Aug;16(7):475-81. Medline Abstract

Thanos PK, Taintor NB, Rivera SN, Umegaki H, Ikari H, Roth G, Ingram DK, Hitzemann R, Fowler JS, Gatley SJ, Wang GJ, Volkow ND.
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking.
Alcohol Clin Exp Res. 2004 May;28(5):720-8. Medline Abstract

Volkow ND, Fowler JS, Wang GJ, Swanson JM.
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications.
Mol Psychiatry. 2004 Jun;9(6):557-69. Medline Abstract

Volkow ND, Fowler JS, Wang GJ.
The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies.
Neuropharmacology. 2004;47 Suppl 1:3-13. Medline Abstract

Volkow ND, Wang GJ, Fowler JS, Telang F, Maynard L, Logan J, Gatley SJ, Pappas N, Wong C, Vaska P, Zhu W, Swanson JM.
Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain.
Am J Psychiatry. 2004 Jul;161(7):1173-80. Medline Abstract

Wang GJ, Volkow ND, Telang F, Jayne M, Ma J, Rao M, Zhu W, Wong CT, Pappas NR, Geliebter A, Fowler JS.
Exposure to appetitive food stimuli markedly activates the human brain.
Neuroimage. 2004 Apr;21(4):1790-7. Medline Abstract

Wang GJ, Volkow ND, Thanos PK, Fowler JS.
Similarity between obesity and drug addiction as assessed by neurofunctional imaging: a concept review.
J Addict Dis. 2004;23(3):39-53. Medline Abstract

Wang GJ, Chang L, Volkow ND, Telang F, Logan J, Ernst T, Fowler JS.
Decreased brain dopaminergic transporters in HIV-associated dementia patients.
Brain. 2004 Nov;127(Pt 11):2452-8. Epub 2004 Aug 19. Medline Abstract

Wang GJ, Volkow ND, Chang L, Miller E, Sedler M, Hitzemann R, Zhu W, Logan J, Ma Y and Fowler JS
Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence.
Am J Psychiatry. 2004 Feb;161(2):242-8. Medline Abstract

Woody C, Kriplani A, O'Connor P, Pratte J-F, Radeka V, Rescia S, Schlyer D, Shokouhi S, Stoll S, Vaska P, Villaneuva A, Volkow N, Yu B
RatCAP: A small, head-mounted PET tomograph for imaging the brain of an awake rat.
Nucl Instr Meth A (in press).

Zhu W, Volkow ND , Ma Y, Fowler JS and Wang G-J
Relationship between ethanol-induced changes in brain regional metabolism and its motor, behavioural and cognitive effects.
Alcohol Alcohol. 2004 Jan-Feb;39(1):53-8. Medline Abstract

2003

Alexoff DL, Vaska P, Marsteller D, Gerasimov T, Li J, Logan J, Fowler JS, Taintor NB, Thanos PK, Volkow ND
Reproducibility of 11 C-Raclopride Binding in the Rat Brain Measured with the MicroPET R4: Effects of Scatter Correction and Tracer Specific Activity
J. Nucl. Med., May 2003; 44: 815 - 822. Medline Abstract

Benveniste H, Fowler JS, Rooney WD, Moller DH, Backus WW, Warner DA, Carter P, King P, Scharf B, Alexoff DA, Ma Y, Vaska P, Schlyer D and Volkow ND
Maternal-fetal in vivo imaging: a combined PET and MRI study.
J Nucl Med. 2003 Sep;44(9):1522-30. Medline Abstract

Brodie JD, Figueroa E and Dewey SL
Treating cocaine addiction: from preclinical to clinical trial experience with gamma-vinyl GABA.
Synapse. 2003 Dec 1;50(3):261-5.Medline Abstract

Ding Y-S, Lin KS, Garza V, Carter P, Alexoff D, Logan J, Shea C, Xu Y and King P
Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and in peripheral organs.
Synapse. 2003 Dec 15;50(4):345-52. Medline Abstract

Ding Y-S, Fowler JS, Logan J, Wang G-J, Telang F, Garza V, Biegon A, Pareto D, Rooney W, Volkow ND and Vocci F
6-[ 18 F] fluoro-A-85380, a new PET ligand for the nicotinic acetylcholine receptor: studies in the human brain and demonstration of specific binding in white matter in baboons.
51 st Annual Meeting of the Society of Nuclear Medicine.

Ferrieri RA
Supercritical fluids in medical radioisotope processing and chemistry: Part I, Evolution of Technology and Techniques
J. Label Cmpd & Radiopharm. 2003;46, 893-922

Ferrieri RA
Supercritical fluids in medical radioisotope processing and chemistry: Part II, Applications, Real and Demonstrated
J. Label Cmpd.& Radiopharm. 2003;46, 923-943

Fowler JS, Logan J, Wang G-J, Franceschi D, Volkow ND, Telang F, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, King P, Schlyer D, Gatley SJ, Ding Y-S, Warner D, Netusil N, Carter P, Jayne M, Alexoff D, Zhu W and Vaska P
Monoamine oxidase A imaging in peripheral organs in healthy human subjects.
Synapse. 2003 Sep 1;49(3):178-87. Medline Abstract

Fowler JS, Logan J, Wang GJ, Volkow ND, Telang F, Zhu W, Franceschi D, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, Schlyer D, Gatley SJ, Ding YS, Alexoff D, Warner D, Netusil N, Carter P, Jayne M, King P and Vaska P
Low monoamine oxidase B in peripheral organs in smokers.
Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11600-5. Epub 2003 Sep 12. Medline Abstract

Fowler JS, Logan J, Wang GJ, Franceschi D, Volkow ND, Telang F, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, King P, Schlyer D, Gatley SJ, Ding YS, Warner D, Netusil N, Carter P, Jayne M, Alexoff D, Zhu W, Vaska P
Monoamine oxidase A imaging in peripheral organs in healthy human subjects.
Synapse, Sep 2003; 49(3): 178-87 Medline Abstract

Fowler JS, Logan J, Wang GJ, Volkow ND
Monoamine oxidase and cigarette smoking.
Neurotoxicology, Jan 2003; 24(1): 75-82. Medline Abstract

Fowler JS, Ding YS, Volkow ND
Radiotracers for positron emission tomography imaging.
Semin Nucl Med, Jan 2003; 33(1): 14-27. Medline Abstract

Fowler JS
Radiotracer chemistry in 2002.
J. Nucl. Med., Jan 2003; 44(1): 19N-22N. Medline Abstract

Gatley SJ
Labeled Glucose Analogs in the Genomic Era
J. Nucl. Med., Jul 2003; 44: 1082 - 1086. Medline Abstract

Lee JH, Telang FW, Springer CS Jr, Volkow ND
Abnormal brain activation to visual stimulation in cocaine abusers.
Life Sci, Aug 2003; 73(15): 1953-61. Medline AbstractLi Z, Ding Y-S, Gifford A, Fowler JS and Gatley SJ
Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.
Bioconjug Chem. 2003 Mar-Apr;14(2):287-94. Medline Abstract

Li Z, Ding YS, Gifford A, Fowler JS, Gatley JS
Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.
Bioconjug Chem, Mar 2003; 14(2): 287-94. Medline Abstract

Schiffer WK, Azmoodeh M, Gerasimov M, Volkow ND , Fowler JS and Dewey SL
Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.
Synapse. 2003 Apr;48(1):35-8. Medline Abstract

Schiffer WK, Marsteller D and Dewey SL.
Sub-chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine-induced increases in nucleus accumbens dopamine. Psychopharmacology (Berl). 2003 Jul;168(3):339-43. Epub 2003 Apr 09. Medline Abstract

Schiffer WK, Logan J, Dewey SL
Positron Emission Tomography Studies of Potential Mechanisms Underlying Phencyclidine-Induced Alterations in Striatal Dopamine.
Neuropsychopharmacology. 2003 Dec;28(12):2192-8. Medline Abstract

Schiffer WK, Marsteller D, Dewey SL
Sub-chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine-induced increases in nucleus accumbens dopamine.
Psychopharmacology (Berl), Jul 2003; 168(3): 339-43. Medline Abstract

Schiffer WK, Azmoodeh M, Gerasimov M, Volkow ND, Fowler JS, Dewey SL
Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.
Synapse, Apr 2003; 48(1): 35-8. Medline Abstract

Shokouhi S, Stoll SP, Villanueva A, Vaska P, Schlyer DJ, Woody CL, Yu B, O'Connor P, Pratte J-F, Radeka V, Volkow N, and Fowler JS
A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies.
IEEE Trans. Nucl. Sci. 2003, 50 (5), 1457-61.

Studenov AR , Szalda DE and Ding Y-S
Synthesis of no-carrier-added C-11 labeled D- and L-enantiomers of phenylalanine and tyrosine for comparative PET studies.
Nucl Med Biol. 2003 Jan;30(1):39-44. Medline Abstract

Vaska P, Stoll SP, Woody CL, Schlyer DJ, and Shokouhi S
Effects of Inter-Crystal Cross-Talk on Multi-Element LSO/APD PET Detectors.
IEEE Transactions on Nuclear Science 2003, 50 (3), 362-366.

Volkow ND , Wang G-J, Maynard L, Jayne M, Fowler JS, Zhu W, Logan J, Gatley SJ, Ding YS, Wong C and Pappas N
Brain dopamine is associated with eating behaviors in humans.
Int J Eat Disord. 2003 Mar;33(2):136-42. Medline Abstract

Volkow ND , Fowler JS and Wang G-J
The addicted human brain: insights from imaging studies.
J Clin Invest. 2003 May;111(10):1444-51. Medline Abstract

Volkow ND , Fowler JS and Wang G-J
Positron emission tomography and single-photon emission computed tomography in substance abuse research.
Semin Nucl Med. 2003 Apr;33(2):114-28. Medline Abstract

Volkow ND , Wang G-J, Fowler JS, Molina PE , Logan J, Gatley SJ, Gifford A, Ding Y-S, Wong C, Pappas NR, Zhu W and Swanson JM
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma. Psychopharmacology (Berl). 2003 Mar;166(3):264-70. Epub 2003 Feb 13. Medline Abstract

Volkow ND, Wang G-J, Ma Y, Fowler JS, Zhu W, Maynard L, Telang F, Vaska P, Ding Y-S, Wong C and Swanson JM
Expectation enhances the regional brain metabolic and the reinforcing effects of stimulants in cocaine abusers.
J Neurosci. 2003 Dec 10;23(36):11461-8. Medline Abstract

Wang G-J, Volkow ND , Thanos PK and Fowler JS
PET evidence of similarity between obesity and drug addiction.
Psychiatric Annals 2003;33(2), 104-111.

Wang GJ, Volkow ND, Fowler JS, Franceschi D, Wong CT, Pappas NR, Netusil N, Zhu W, Felder C, Ma Y
Alcohol intoxication induces greater reductions in brain metabolism in male than in female subjects.
Alcohol Clin Exp Res, Jun 2003; 27(6): 909-17. Medline Abstract

Volkow ND, Fowler JS, Wang GJ
The addicted human brain: insights from imaging studies
J. Clin. Invest., May 2003; 111: 1444 - 1451. Medline Abstract

Volkow ND, Fowler JS, Wang GJ
Positron emission tomography and single-photon emission computed tomography in substance abuse research.
Semin Nucl Med, Apr 2003; 33(2): 114-28. Medline Abstract

Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, Sedler M, Logan J, Franceschi D, Gatley J, Hitzemann R, Gifford A, Wong C, Pappas N
Low Level of Brain Dopamine D 2 Receptors in Methamphetamine Abusers: Association With Metabolism in the Orbitofrontal Cortex
Focus, Apr 2003; 1: 150 - 157. Medline Abstract

Volkow ND, Wang GJ, Maynard L, Jayne M, Fowler JS, Zhu W, Logan J, Gatley SJ, Ding YS, Wong C, Pappas N
Brain dopamine is associated with eating behaviors in humans.
Int J Eat Disord, Mar 2003; 33(2): 136-42. Medline Abstract

Volkow ND, Wang GJ, Fowler JS, Molina PE, Logan J, Gatley SJ, Gifford A, Ding YS, Wong C, Pappas NR, Zhu W, Swanson JM
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma.
Psychopharmacology (Berl), Mar 2003; 166(3): 264-70. Medline Abstract

2002

Ashby CR Jr, Paul M, Gardner EL, Gerasimov MR, Dewey SL, Lennon IC, Taylor SJ
Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats.
Synapse, May 2002; 44(2): 61-3. Medline Abstract

Beck B, Plant DH, Grant SC, Thelwall PE, Silver X, Mareci TH, Benveniste H, Smith M, Collins C, Crozier S, Blackband SJ
Progress in high field MRI at the University of Florida.
MAGMA. 2002 Jan;13(3):152-7. Medline Abstract

Benveniste H, Blackband S
MR microscopy and high resolution small animal MRI: applications in neuroscience research.
Prog Neurobiol. 2002 Aug;67(5):393-420. Medline Abstract

Fowler JS, Logan J, Wang GJ, Volkow ND, Zhu W, Franceschi D, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, MacGregor RR, Schlyer D, Gatley SJ, Ding YS, Alexoff D
PET Imaging of Monoamine Oxidase B in Peripheral Organs in Humans
J. Nucl. Med., Oct 2002; 43: 1331 - 1338. Medline Abstract

Fowler JS, Logan J, Volkow ND, Wang GJ, MacGregor RR, Ding YS
Monoamine oxidase: radiotracer development and human studies.
Methods, Jul 2002; 27(3): 263-77. Medline Abstract

Fowler JS, Ido T
Initial and subsequent approach for the synthesis of 18FDG.
Semin Nucl Med, Jan 2002; 32(1): 6-12. Medline Abstract

Gardner EL, Schiffer WK, Horan BA, Highfield D, Dewey SL, Brodie JD, Ashby CR Jr
Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats.
Synapse, Dec 2002; 46(4): 240-50. Medline Abstract

Gerasimov MR, Logan J, Ferrieri RA, Muller RD, Alexoff D, Dewey SL
Effect of vehicle on brain uptake of [11C]toluene.
Nucl Med Biol, Jul 2002; 29(5): 607-12. Medline Abstract

Gerasimov MR, Ferrieri RA, Schiffer WK, Logan J, Gatley SJ, Gifford AN, Alexoff DA, Marsteller DA, Shea C, Garza V, Carter P, King P, Ashby CR Jr, Vitkun S, Dewey SL
Study of brain uptake and biodistribution of [11C]toluene in non-human primates and mice.
Life Sci, Apr 2002; 70(23): 2811-28. Medline Abstract

Gerasimov MR, Schiffer WK, Marstellar D, Ferrieri R, Alexoff D, Dewey SL
Toluene inhalation produces regionally specific changes in extracellular dopamine.
Drug Alcohol Depend, Feb 2002; 65(3): 243-51. Medline Abstract

Gifford AN, Makriyannis A, Volkow ND, Gatley SJ
In vivo imaging of the brain cannabinoid receptor.
Chem Phys Lipids, Dec 2002; 121(1-2): 65-72. Medline Abstract

Goldstein RZ, Volkow ND
Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Am. J. Psychiatry, Oct 2002; 159: 1642 - 1652. Medline Abstract

Goldstein RZ, Volkow ND, Chang L, Wang GJ, Fowler JS, Depue RA, Gur RC
The orbitofrontal cortex in methamphetamine addiction: involvement in fear.
Neuroreport, Dec 2002; 13(17): 2253-7. Medline Abstract

Greenhill L, Beyer DH, Finkleson J, Shaffer D, Biederman J, Conners CK, Gillberg C, Huss M, Jensen P, Kennedy JL, Klein R, Rapoport J, Sagvolden T, Spencer T, Swanson JM, Volkow N
Guidelines and algorithms for the use of methylphenidate in children with Attention-Deficit/ Hyperactivity Disorder.
J Atten Disord, Jan 2002; 6 Suppl 1: S89-100. Medline Abstract

Horan B, Gifford AN, Matsuno K, Mita S, Ashby CR Jr
Effect of SA4503 on the electrically evoked release of (3)H-acetylcholine from striatal and hippocampal rat brain slices.
Synapse, Oct 2002; 46(1): 1-3. Medline Abstract

Logan J, Fowler JS, Ding YS, Franceschi D, Wang GJ, Volkow ND, Felder C, Alexoff D
Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase A tracers [11C]clorgyline and deuterium-substituted [11C]clorgyline.
J Cereb Blood Flow Metab, Nov 2002; 22(11): 1367-76. Medline Abstract

Marsteller DA, Gerasimov MR, Schiffer WK, Geiger JM, Barnett CR, Borg JS, Scott S, Ceccarelli J, Volkow ND, Molina PE, Alexoff DL, Dewey SL
Acute handling stress modulates methylphenidate-induced catecholamine overflow in the medial prefrontal cortex.
Neuropsychopharmacology, Aug 2002; 27(2): 163-70. Medline Abstract

Muller RD, Ferrieri RA, Gerasimov M, Garza V
Supercritical CO2 fluid radiochromatography system used to purify [11C]toluene for PET.
Nucl Med Biol, Apr 2002; 29(3): 351-7. Medline Abstract

Rice OV, Gordon N, Gifford AN
Conditioned place preference to morphine in cannabinoid CB1 receptor knockout mice.
Brain Res, Jul 2002; 945(1): 135-8. Medline Abstract

Swanson JM, Volkow ND
Pharmacokinetic and pharmacodynamic properties of stimulants: implications for the design of new treatments for ADHD.
Behav Brain Res, Mar 2002; 130(1-2): 73-8. Medline Abstract

Thanos PK, Taintor NB, Alexoff D, Vaska P, Logan J, Grandy DK, Fang Y, Lee JH, Fowler JS, Volkow ND, Rubinstein M
In Vivo Comparative Imaging of Dopamine D2 Knockout and Wild-Type Mice with 11 C-Raclopride and MicroPET
J. Nucl. Med., Nov 2002; 43: 1570 - 1577. Medline Abstract

Volkow ND, Gatley SJ, Fowler JS, Wang GJ, Swanson J
Serotonin and the therapeutic effects of ritalin.
Science. 2000 Apr 7;288(5463):11. Medline Abstract

Volkow ND, Wang GJ, Maynard L, Fowler JS, Jayne B, Telang F, Logan J, Ding YS, Gatley SJ, Hitzemann R, Wong C, Pappas N
Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study.
Psychiatry Res, Dec 2002; 116(3): 163-72. Medline Abstract

Volkow ND, Fowler JS, Wang GJ, Ding YS, Gatley SJ
Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies.
Eur Neuropsychopharmacol, Dec 2002; 12(6): 557-66. Medline Abstract

Volkow ND, Fowler JS, Wang GJ, Goldstein RZ
Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies.
Neurobiol Learn Mem, Nov 2002; 78(3): 610-24. Medline Abstract

Volkow ND, Wang GJ, Fowler JS, Thanos PP, Logan J, Gatley SJ, Gifford A, Ding YS, Wong C, Pappas N
Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study.
Synapse, Nov 2002; 46(2): 79-82. Medline Abstract

Volkow ND, Fowler JS, Wang GJ
Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies.
Behav Pharmacol, Sep 2002; 13(5-6): 355-66. Medline Abstract

Volkow ND, Wang GJ, Fowler JS, Logan J, Jayne M, Franceschi D, Wong C, Gatley SJ, Gifford AN, Ding YS, Pappas N
"Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect.
Synapse, Jun 2002; 44(3): 175-80. Medline Abstract

Volkow ND, Wang GJ, Fowler JS, Logan J, Franceschi D, Maynard L, Ding YS, Gatley SJ, Gifford A, Zhu W, Swanson JM
Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: therapeutic implications.
Synapse, Mar 2002; 43(3): 181-7. Medline Abstract

Volkow ND, Fowler JS, Wang G, Ding Y, Gatley SJ
Mechanism of action of methylphenidate: insights from PET imaging studies.
J Atten Disord, Jan 2002; 6 Suppl 1: S31-43. Medline Abstract

Volkow ND, Zhu W, Felder CA, Mueller K, Welsh TF, Wang GJ, de Leon MJ
Changes in brain functional homogeneity in subjects with Alzheimer's disease.
Psychiatry Res, Feb 2002; 114(1): 39-50 Medline Abstract

Wang GJ, Volkow ND, Fowler JS
The role of dopamine in motivation for food in humans: implications for obesity.
Expert Opin Ther Targets, Oct 2002; 6(5): 601-9. Medline Abstract

Wang GJ, Volkow ND, Felder C, Fowler JS, Levy AV, Pappas NR, Wong CT, Zhu W, Netusil N
Enhanced resting activity of the oral somatosensory cortex in obese subjects.
Neuroreport, Jul 2002; 13(9): 1151-5. Medline Abstract

Woody CL, Stoll SP, Schlyer DJ, Gerasimov M, Vaska P, Volkow N, Fowler JS and Dewey SL
A study of scintiallation beta microprobes.
IEEE Transactions in Nuclear Science, 2002; 49, 2208-2212.

Zhang Z, Ding Y-S, Studenov AR , Gerasimov MR and Ferrieri R
Novel synthesis of [1- 11 C]-?aminobutyric acid ([1- 11 C]GVG) for pharmacokinetic studies of addiction treatment.
J. of Labeled Compounds and Radiopharmaceuticals, 2002; 45, 199-211.

Last Modified: January 31, 2008