Volume 12, Number 6, June 2006

Genetic Divergence of Toxoplasma gondii Strains Associated with Ocular Toxoplasmosis, Brazil

Asis Khan,* Catherine Jordan,* Cristina Muccioli,† Adriana L. Vallochi,‡ Luiz V. Rizzo,‡ Rubens Belfort Jr,† Ricardo W.A. Vitor,§ Claudio Silveira,¶ and L. David Sibley*
*Washington University School of Medicine, St. Louis, Missouri, USA; †Paulista School of Medicine, São Paulo, Brazil; ‡University of São Paulo, São Paulo, Brazil; §Federal University of Minas Gerais, Belo Horizonte, Brazil; and ¶Clinica Silveira, Erechim, Brazil

Figure 4. A phylogram of 35 Toxoplasma gondii strains was constructed from a Clustal alignment of UPRT-1 intron sequences using the phylogenetic analysis program PAUP*4.0b (22). The BioNeighbor-Joining algorithm was used to determine the divergence distance among different strains and generate an unrooted phylogram. Consensus trees were bootstrapped for 1,000 replicates and drawn with an arbitrary root according to the 50% majority rule. Strain designations are shown in the Table. A complete listing of intron sequences is found in Appendix Figure.

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This page last reviewed May 17, 2006

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention