Volume 11, Number 6, June 2005

Relative Fitness of Fluoroquinolone-resistant Streptococcus pneumoniae

Crystal N. Johnson,* David E. Briles,* William H. Benjamin Jr.,* Susan K. Hollingshead,* and Ken B. Waites*
*University of Alabama at Birmingham, Birmingham, Alabama, USA

Figure 3. Percentage recovery units (PRUs: CFUs recovered from nasal wash or lung homogenate divided by CFUs originally used to infect mice and multiplied by 10⁶) for competitive pneumonia infection with Streptococcus pneumoniae EF3030 and the Phe/Phe mutant (A), EF3030 and the Phe/Tyr mutant (B), and noncompetitive pneumonia with EF3030, Phe/Phe, and Phe/Tyr (C). Lines connect data from the same mouse. Bars indicate median PRUs. NP, nasopharynx. p values were calculated by the Wilcoxon matched-pairs signed-rank test (A and B) and the Mann-Whitney unpaired 2-tailed test (C).

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This page last reviewed May 17, 2005

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
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