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(...muh-LIG-nunt meh-zuh-thee-lee-OH-muh)
![](https://webarchive.library.unt.edu/eot2008/20090514071922im_/http://www.cancer.gov/images/spacer.gif)
| Cancer has spread to distant organs or tissues. Stage IV malignant mesothelioma is advanced malignant mesothelioma. |
Previous Definitions: | stage IV gastric cancer, stage IV hypopharynx cancer, stage IV kidney cancer, stage IV laryngeal cancer, stage IV lip and oral cavity cancer | Next Definitions: | stage IV melanoma, stage IV mycosis fungoides and the Sézary syndrome, stage IV nasopharyngeal cancer, stage IV non-small cell lung cancer, stage IV nonmelanoma skin cancer |
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![](https://webarchive.library.unt.edu/eot2008/20090514071922im_/http://www.cancer.gov/images/spacer.gif) |