| Title: |
Cortical interneurons and pyramidal cells in neurovascular coupling responses to afferent pathway simulation [electronic resource] / Edith Hamel. |
| Author(s)/Name(s): |
Hamel, E. (Edith) |
| Publisher: |
[Bethesda, Md. : National Institutes of Health, 2007] |
| Related Names: |
National Institutes of Health (U.S.) |
| Language: |
eng |
| Electronic Links: |
http://videocast.nih.gov/launch.asp?13570 |
| MeSH Subjects: |
Cerebrovascular Circulation |
|
Brain --blood supply |
|
Interneurons --physiology |
|
Pyramidal Cells --physiology |
|
Afferent Pathways --physiology |
|
Vasomotor System --physiology |
|
Lectures |
| Summary: |
(CIT): Dr. Hamel and her colleagues study neurons and glial cells in the brain can locally influence the brain’s blood supply. The dysfunction/degeneration of specific populations of cells may have dramatic repercussions on the local regulation of blood flow. Tract tracing studies and immunocytochemistry are used to study the anatomical relationships between neurons and blood vessels as well as the cellular localization, molecular composition, and pharmacological properties of receptors mediating vasomotor responses. The goal of this work is to understand how brain neurons control local cerebral perfusion and how this relationship is altered in pathological states like Alzheimer’s Disease and migraine headache. Ultimately, new drugs could be developed to preserve a normal blood supply to the brain in the absence of neurogenic regulation. NIH Neuroscience Seminar Series. |
| Notes: |
Title from screen banner (viewed Feb. 13, 2007). |
|
Streaming video (1 hr., 11 min., 35 sec. : sd., col.). |
|
Mode of access: World Wide Web. |
|
Open-captioned. |
| NLM Unique ID: |
101298612 |
| Other ID Numbers: |
(DNLM)CIT:13570 |
