NOTICE: MINIATURIZATION OF ASSAYS FOR PHENOTYPING SMALL ANIMAL MODELS UTILIZING THE SBIR AND STTR MECHANISMS

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is interested in encouraging, through the SBIR/STTR programs, the development of miniaturized assays that can be used to measure metabolites, ions, hormones and other signals in very small volumes of tissue. Microassays developed pursuant to this Notice should be useful for longitudinal metabolic or physiologic studies in small animal (mouse) models of disease, or in human subjects. These assays should ideally be inexpensive, reproducible, and either automated or easily implemented in a variety of disease models and laboratory settings. Although it is impossible to foresee all assays that will be needed to phenotype very specialized animal models, it is possible to establish a set of standardized assays that can be used in a very large variety of mouse models.

This research topic is of special interest to the NIDDK and is identified in the NIH Omnibus Solicitation for SBIR Grant Applications. Additional information about this research topic can be found at the following URL: http://grants.nih.gov/grants/guide/notice-files/NOT-DK-00-002.html. Annual application receipt dates are: April 1, August 1 and December 1.