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Figure 4. Performance of the HEPA/vaccine plan under the base-case
scenario. The horizontal axes in plots A-C are the number of floor samples
per round ( ). Each of plots A–C have 4 curves, 1 for
each value of the floor concentration threshold ( ). Cleaning stops after
the estimated floor concentration from samples per room is
below the threshold . The vertical axes in plots A-C are A)
the mean number of inhalation anthrax cases, B) the mean cost, and C)
the mean recovery time. In plots A-C, the concentration threshold ( ) has a much bigger
impact than the number of samples per room ( ) on these 3 performance measures.
Plot D shows the tradeoff of anthrax cases versus recovery time in the
base case. The number of samples per room is assumed to be = 1 in this plot, which
is derived from plots A–C. Plot D also contains tradeoff curves for 3
sensitivity analyses: a lower air-cleaning rate, increased sampling variability
of spore concentration, and the most severe of the 92 cases depicted in
Figure 3B. This plot shows that the cases
versus time tradeoff curve is very insensitive to changes in the air-cleaning
rate and sampling variability.
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