Dr. Henry M. Kronenberg will deliver the fourth lecture in NIDCR’s seminar series on Friday, July 11 at 2 p.m. in Lipsett Amphitheater, Bldg. 10. His talk is titled “Parathyroid Hormone: Builder and Destroyer of Bone.” He will describe his work on the role of parathyroid hormone (PTH) and its receptor in the regulation of bone formation and remodeling.

To begin to define in vivo the mechanisms of the varying actions of PTH, Kronenberg and his colleagues have developed genetically altered mice with defects in specific signaling pathways activated by the PTH receptor. These mice represent important tools for learning about the pathways responsible for the bone-forming and bone-resorbing actions of PTH.

Kronenberg is chief of the endocrine unit at Massachusetts General Hospital and professor of medicine at Harvard Medical School. He has won numerous awards including the Fuller Albright Young Investigator Award and the William F. Neuman Award of the American Society for Bone and Mineral Research (ASBMR). He has served as ASBMR president and as a member of the board of directors of the International Bone and Mineral Society. He has also served on the Endocrine Society Council and is currently the society’s vice president for basic science as well as its representative on the FASEB board of directors. Kronenberg is also a member of the NIDCR board of scientific counselors.

The lecture is part of the NIDCR Seminar Series “From Basic Research to Therapy—The Latest Frontier.” The series focuses on research topics of broad interest to the NIH community. The lecture is open to all employees. Sign language interpretation will be provided. Those who need reasonable accommodation to participate should contact Mary Daum, Mary.Daum@nih.gov, (301) 594-7559; and/or the Federal Relay (1-800-877-8339).