| Disease/Syndrome |
Solvents, acute toxic effect |
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| Category |
Acute Poison |
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| Acute/Chronic |
Acute-Moderate |
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| Biomedical References |
Search PubMed |
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| Comments |
Organic solvents are volatile substances, usually liquid at room temperature, commonly used in the workplace as ingredients in paints and adhesives. They are often used as cleaners and degreasers. "The potency of solvents as general anesthetics and as defatting agents is directly proprtionate to their lipid solubility." The systemic symptoms of acute solvent poisoning resemble those of intoxication from alcoholic beverages. [LaDou, p. 481-7]
Like HARD liquor, organic solvents can cause:
H--hepatotoxicity; heart sensitization;
A--anesthesia;
R--respiratory irritation; reaction time increased;
D--dermatitis;
Biological monitoring of exposed workers may be preferable to air monitoring because solvent uptake is greatly influenced by workload. [Zenz, p. 772]
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| Latency/Incubation |
Seconds to hours |
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| Diagnostic |
Biological exposure indices (BEIs) for benzene, toluene, xylene, styrene, methyl chloroform (1-1-1-trichloroethane), and dimethylformamide; [ACGIH] |
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| ICD-9 Code |
987.8 |
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| Reference Link |
OSHA Technical Links - Solvents |
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| Related Information in Haz-Map |
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| Symptoms/Findings |
Symptoms/Findings associated with this disease:
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| Job Tasks |
High risk job tasks associated with this disease:
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| Agents |
Hazardous agents that cause the occupational disease:
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