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 Thursday, June 28, 2007 Volume 18   Number 26
Weekly Update banner Family History Population Research Genomics in Practice General Public Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genetic research on disease prevention & public health.
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Seeking Nominations for the EGAPP Stakeholders Group (ESG)
Nominations are requested for stakeholder representatives to participate in a stakeholders group that will work with the CDC-sponsored EGAPP pilot project. The deadline for nominations is July 18, 2007.
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blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
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Genomics Announcements
   
CDC sponsored material

New article on "An automatic method to generate domain-specific investigator networks using PubMed abstracts" written by Wei Yu, PhD, Ajay Yesupriya, MPH, Anja Wulf, Junfeng Qu, PhD, Marta Gwinn, MD, MPH, and Muin Khoury, MD, PhD, was published in the June 20, 2007 issue of BMC Medical Informatics and Decision Making.

   
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Thirteenth Meeting of the Secretary’s Advisory Committee on Genetics, Health, and Society, July 10, 2007

   


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
   Cancer

A genetic factor predicts prognosis in brain tumor patientsnon-gov warning icon EurekAlert, June 27, 2007

Inherited genes linked to toxicity of leukemia therapynon-gov warning icon Medical News Today, June 24, 2007

Gene Chips Reveal Different Patterns Of Lymph Node Spread In Lung Cancernon-gov warning icon Medical News Today, June 27, 2007 Targeting key proteins of carcinogenesisnon-gov warning icon EurekAlert, June 22, 2007

New genetic marker characterizes aggressiveness of cancer cellsnon-gov warning icon Bioresearch Online, June 26, 2007

Mathematics reveals genetic pattern of tumor growthnon-gov warning icon Today@UCI, June 21

Researchers track influence of cancer inhibitor on single DNA moleculenon-gov warning icon Science Daily, June 26, 2007

 
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Chronic Diseases Genetic Testing
Gene variant increases risk for alcoholism following childhood abusenon-gov warning icon EurekAlert, June 26, 2007

Genetic testing could tailor individual dietsnon-gov warning icon The Australian, June 27, 2007

Parkinson's gene therapy breakthrough may enter clinical trials by year-endnon-gov warning icon Medical News Today, June 26, 2007  

Scientists identify first gene linked to scoliosis,  non-gov warning icon EurekAlert, June 25, 2007

 

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Other News
Men and women equally transmit genetic risk of MS to their children,  non-gov warning icon EurekAlert, June 27 Genes raise post-vaccination fever risknon-gov warning icon (last accessed 2/2008) HealthDay, June 22, 2007
Gene therapy for Parkinson's disease is safe and some patients benefit, lancet study shows,  non-gov warning icon Medical News Today, June 27

Healthcare IT sector to exploit human genome researchnon-gov warning icon PRNewswire, June 26, 2007 (last accessed 01/2008)

Humans have spread globally, and evolved
locally
non-gov warning icon The New York Times, June 26, 2007

Genes play unexpected role in their own
activation
, non-gov warning icon Medical News Today, June 24, 2007

CLC bio, BGI and SDG join forces in
bioinformatics
, non-gov warning icon OBBeC, June 25, 2007

 
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Genomics in Scientific Literature
Featured Item

Association between Q551R IL4R genetic variants and atopic asthma risk demonstrated by meta-analysis
Loza MJ & Chang BL
J Allergy Clin Immunol 2007 Jun

 General Articles

Acetaldehyde, polymorphisms and the cardiovascular system
Yin SJ & Peng GS
Novartis Found Symp 2007;285:52-63; discusion 63-8, 198-9

Genetic, pathogenetic, and phenotypic implications of the mitochondrial A3243G tRNALeu(UUR) mutation
Finsterer J
Acta Neurol Scand 2007 Jul;116(1):1-14

HaploBuild: An algorithm to construct noncontiguous associated haplotypes in family-based genetic studies
Laramie JM, et al.
Bioinformatics 2007 Jun

Evaporative cooling feature selection for genotypic data involving interactions
McKinney BA, et al.
Bioinformatics 2007 Jun

Cytokine gene polymorphism and progression of renal and cardiovascular diseases
Rao M, et al.
Kidney Int 2007 Jun

Pharmacogenetics and smoking cessation with nicotine replacement therapy
Ray R, et al.
CNS Drugs 2007;21(7):525-33

 Family History

None this week.

 

 Genetic Testing

A randomized controlled trial of a brief self-help coping intervention designed to reduce distress when awaiting genetic risk information
Bennett P, et al.
J Psychosom Res 2007 Jul;63(1):59-64

Hereditary Thrombophilia and Venous Thromboembolism: Critical Evaluation of the Clinical Implications of Screening
Mazzolai L & Duchosal MA
Eur J Vasc Endovasc Surg 2007 Jun

Deciphering the role of heterozygous mutations in genes associated with parkinsonism
Klein C, et al.
Lancet Neurol 2007 Jul;6(7):652-62

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending June 27, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases

Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Diseases of the Musculoskeletal System and Connective Tissue
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 

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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
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This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.
Page last reviewed: June 28, 2007 (archived document)
Content Source: National Office of Public Health Genomics