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 Thursday, July 12, 2007 Volume 19   Number 2
Weekly Update banner Family History Population Research Genomics in Practice General Public Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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Seeking Nominations for the EGAPP Stakeholders Group (ESG)
Nominations are requested for stakeholder representatives to participate in a stakeholders group that will work with the CDC-sponsored EGAPP pilot project. The deadline for nominations is July 18, 2007.
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View Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 

 

 

 

 

Genomics Announcements
   
CDC sponsored material

New CDC funding opportunity "Reporting DNA-Based Genetic Test Results Applicable to Heritable Conditions and/or Markers of Drug Metabolism: The Clinical Laboratory Report as a Decision-Support Tool"

   
CDC sponsored material

July public health genomics seminar presented by CDC
July 26, 2007, Rockville, MD (ENVISION – Atlanta, GA)
“But how do we translate new genetic knowledge into practice?"

   
CDC sponsored material

What's New in HuGENet™
July 2007

   


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
line
   Cancer

BRCA gene does not increase breast cancer death, new studynon-gov warning icon Medical News Today, July 12

Chromosome linked to colorectal cancer
identified
non-gov warning icon News-Medical.Net, July 9

Search for genes associated with colon cancer makes major advancenon-gov warning icon Medical News Today, July 11

Prostate cancer gene also raises colon cancer
risk
non-gov warning icon (last accessed 2/2008) Medline Plus, July 9

ERG gene's activity points to more lethal subtype of acute myeloid leukemianon-gov warning icon News-Medical.Net, July 10

Scientists discover first common bowel cancer genenon-gov warning icon News-Medical.Net, July 9

line

   Mental Health    Genetic Testing

Dementia gene mutation identifiednon-gov warning icon (last accessed 2/2008) Medline Plus, July 9

Breast Cancer Gene Testing May Be Appropriate For More Young Breast Cancer Patientsnon-gov warning icon Medical News Today, July 12

The gregarious brainnon-gov warning icon International Herald Tribune, July 8

Nearly 90 percent of babies receive recommended newborn screening testsnon-gov warning icon EurekAlert, July 10

line

   ELSI (Ethical, Legal and Social Issues)

Who should "own" genetic information?non-gov warning icon Medical News Today, July 6

 

line

   Chronic Disease

Some smokers have genetic predisposition to develop COPD, research showsnon-gov warning icon EurekAlert, July 11

MS susceptibility affected by genetic differences among ethnic groupsnon-gov warning icon Medical News Today, July 7

Men and women equally transmit genetic risk of MS to their childrennon-gov warning icon Medical News Today, July 7

Researchers discover new asthma genenon-gov warning icon Medical News Today, July 7

line

   Other News

Discovery of gallstone genenon-gov warning icon News-Medical.Net, July 11

Study examines cause of hearing loss for patients with certain genetic diseasenon-gov warning icon Science Daily,
July 7

Experts brainstorm over rare genetic disorders,  Yahoo, July 10

Expanding the genetic code in living mammalian cellsnon-gov warning icon Medical News Today, July 6

Preimplantation genetic diagnosis pioneers from the USA and Europe refute New England Journal of Medicine articlenon-gov warning icon Medical News Today, July 10

Novel genetics research advances possibility of HIV vaccinenon-gov warning icon Medical News Today, July 6

Penn researchers discover how microRNAs control protein synthesisnon-gov warning icon Penn Medicine, July 9 NIEHS researchers identify enzyme critical in DNA replicationnon-gov warning icon NIH News, July 5
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Genomics in Scientific Literature
Featured Item

Online genetic databases informing human genome epidemiology
Frodsham AJ & Higgins JP
BMC Med Res Methodol 2007 Jul;7(1):31

   General Articles

[Impact of pharmacogenetics on interindividual variability in the response to vitamin K antagonist therapy.]
Siguret V
Pathol Biol (Paris) 2007 Jul

Host genetics: fine-tuning innate signaling
Fellay J & Goldstein DB
Curr Biol 2007 Jul;17(13):R516-8

Applicability of DNA pools on 500K SNP microarrays for cost-effective initial screens in genomewide association studies
Docherty SJ, et al.
BMC Genomics 2007 Jul;8(1):214

UGT1AI*6 and UGT1A1*27 for individualized irinotecan chemotherapy
Ando Y, et al.
Curr Opin Mol Ther 2007 Jun;9(3):258-62

Health Beliefs and Behaviors of Women Who Have Received Genetic Counseling For Breast Cancer
Rees G, et al.
J Genet Couns 2007 Jul

Process and outcome in communication of genetic information within families: a systematic review
Gaff CL, et al.
Eur J Hum Genet 2007 Jul

Midwives' views of the importance of genetics and their confidence with genetic activities in clinical practice: implications for the delivery of genetics education
Metcalfe A, et al.
J Clin Nurs 2007 Jun

Genetic polymorphisms of human beta-adrenergic receptor genes and their association with obesity
Liu ZQ, et al.
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 Jun;32(3):359-67

Genetic testing to identify high-risk populations for chemoprevention studies
Velasquez JL & Lipkin SM
Cancer Biomark 2007;3(3):163-8

Pharmacogenomics of statin response
Mangravite LM & Krauss RM
Curr Opin Lipidol 2007 Aug;18(4):409-14

Recent development in pharmacogenomics: from candidate genes to genome-wide association studies
Grant SF & Hakonarson H
Expert Rev Mol Diagn 2007 Jul;7(4):371-93

Alcohol dehydrogenase 1B genotype and fetal alcohol syndrome: a HuGE minireview
Green RF & Stoler JM
Am J Obstet Gynecol 2007 Jul;197(1):12-25

Identification of women with an increased risk of developing radiation-induced breast cancer
Cardis E, et al.
Breast Cancer Res 2007 Jun;9(3):106

 

   Family History

The impact of family history of diabetes on risk factors for gestational diabetes
Retnakaran R, et al.
Clin Endocrinol (Oxf) 2007 Jul

Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study
Hippisley-Cox J, et al.
BMJ 2007 Jul

 

   Genetic Testing

Maternal Psychological Reaction to Newborn Genetic Screening for Type 1 Diabetes
Kerruish NJ, et al.
Pediatrics 2007 Jul

How does the collection of genetic test results affect research participants?
Wendler D & Pentz R
Am J Med Genet A 2007 Jul

The Theory of Genetic Vulnerability: A Roy Model Exemplar
Hamilton, RJ. et al
Nursing Science Quarterly 2007 Jul

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending July 11, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases

Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period

For more information on HuGE, please visit the HuGENet™ home page

 

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 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.
Page last reviewed: July 12, 2007 (archived document)
Content Source: National Office of Public Health Genomics