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 Thursday, August 9, 2007 Volume 19   Number 6
Weekly Update banner Family History Population Research Genomics in Practice General Public Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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photo of a weight scale, jump rope and towel Obesity and Genetics
Population genetic changes are too slow to be blamed for the rapid rise in obesity in the United States and many other countries; however,genes do play a role in the development of obesity. Read more...
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 

 

 

 

 

Genomics Announcements
   
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NHGRI solicits applications from academic institutions, community-based organizations, and other organizations for the 2008 Community Genetics Forum, a community engagement project that encourages and supports genetics education and public participation.

   


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Lab on a Chip for Oral Cancer Shows Promisenon-gov warning icon NIH News,
August 8

Aggressive therapy best for certain acute myeloid leukemia patientsnon-gov warning icon News-Medical.Net, August 5
Deadly inheritance, desperate trade-offnon-gov warning icon New York Times, August 7 Specific microRNA, called miR-21, helps liver cancer developnon-gov warning icon News-Medical.Net, August 5

New lung tumor-suppressor gene discovered,  non-gov warning icon Science Daily, August 6

Gene fusion subtypes in prostate carcinoma have clinical implicationsnon-gov warning icon Medical News Today, August 3

Cardiovascular Disease

Genetic Testing

Genetic variations increase risk of heart disease, experts saynon-gov warning icon Earthtimes.org, August 5

Perkinelmer reaches major milestone in the identification of newborns at risk for genetic disordersnon-gov warning icon Bioresearch Online, August 6

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Mental Illness

A pioneering study opens roads for tailor-made antidepressantsnon-gov warning icon EurekAlert, August 6

New databases put wings on search for bipolar risk genesnon-gov warning icon Science Daily, August 3

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Other News

Study finds gender differences in renal and other genes contributing to blood pressurenon-gov warning icon Medical News Today, August 9

Variant of the dopamine receptor gene may be associated with ADHDnon-gov warning icon News-Medical.Net, August 7

Kids inherit fear of unfamiliar food, twin study showsnon-gov warning icon WebMD, August 8

Gene predicts better outcome as cortex normalizes in teens with ADHD, NIH News, non-gov warning icon August 6

Research team enlightens the reasons for severe blindness: newly discovered genetic deficiency cuts the supply for optical cellnon-gov warning icon Medical News Today, August 8

Gene therapy: Identifying where genes can successfully integratenon-gov warning icon Science Daily, August 6
Discovery of active genes reveals new clues on ALSnon-gov warning icon Science Daily, August 7 A genetic string bandnon-gov warning icon Guardian Unlimited, August 3
Genetic factors strongly shape how peers are chosennon-gov warning icon News-Medical.Net, August 7 Gene therapy helps older children with X-linked immunodeficiencynon-gov warning icon Medical Imagining, August 3
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Genomics in Scientific Literature
Featured Item

Rapid ACCE: experience with a rapid and structured approach for evaluating gene-based testing
Gudgeon JM, et al.
Genet Med 2007 Jul;9(7):473-8

 General Articles

Implications of pharmacogenomics in the current and future treatment of asthma
Morrow T
J Manag Care Pharm 2007 Jul-2007 Aug;13(6):497-505

New perspectives for the elucidation of genetic disorders
Ropers HH
Am J Hum Genet 2007 Aug;81(2):199-207

Rapid ACCE: experience with a rapid and structured approach for evaluating gene-based testing
Gudgeon JM, et al.
Genet Med 2007 Jul;9(7):473-8

Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap Project
Nannya Y, et al.
Hum Mol Genet 2007 Jul

Genetic polymorphisms and esophageal cancer risk
Hiyama T, et al.
Int J Cancer 2007 Aug

Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance
Lo HW & Ali-Osman F
Curr Opin Pharmacol 2007 Aug

 

 Genetic Testing

Is genetic testing for Cytochrome P450 Polymorphisms ready for implementation? non-gov warning icon
Matchar DB and Thakur M
American Family Physician 2007 Aug; 76(3)

Genetic screening in 2,710 infertile candidate couples for assisted reproductive  techniques: results of application of Italian guidelines for the appropriate use  of genetic tests
Riccaboni A, et al.
Fertil Steril 2007 Aug

BRCA1/2 mutation testing in breast cancer patients: a prospective study of the long-term psychological impact of approach during adjuvant radiotherapy
Schlich-Bakker KJ, et al.
Breast Cancer Res Treat 2007 Aug

 

 Family History

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis
Lazaridis KN, et al.
Hepatology 2007 Aug

Efficacy of family history in determining thrombophilia risk
Dietrich JE, et al.
J Pediatr Adolesc Gynecol 2007 Aug;20(4):221-4

Positive family history is associated with persistent elevated emotional distress in schizophrenia: Evidence from a 16-month follow-up study
Ritsner MS, et al.
Psychiatry Res 2007 Jul

 
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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending August 8, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases

Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue

For more information on HuGE, please visit the HuGENet™ home page

 

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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
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 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.
Page last reviewed: August 9, 2007 (archived document)
Content Source: National Office of Public Health Genomics