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Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
June 7, 2007
Volume 18, No. 23

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Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Genotype and phenotype in patients with Prader-Willi Syndrome in Taiwan
Lin HY, et al.
Acta Paediatr 2007 Jun;96(6):902-5

Assessment of the prevalence of the 985A>G MCAD mutation in the French-Canadian population using allele-specific PCR
Giroux S, et al.
Clin Genet 2007 Jun;71(6):569-75

 

Infectious and Parasitic Diseases

HLA Polymorphisms and Cervical Human Papillomavirus Infection in a Cohort of Montreal University Students
Mahmud SM, et al.
J Infect Dis 2007 Jul;196(1):82-90

The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania
Ferwerda B, et al.
AIDS 2007 Jun;21(10):1375-7

IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis
Budak F, et al.
Cytokine 2007 Jun

Variants in the promoter region of IKBL/NFKBIL1 gene may mark susceptibility to the development of chronic Chagas' cardiomyopathy among Trypanosoma cruzi-infected individuals
Ramasawmy R, et al.
Mol Immunol 2007 Jun

Protective effect of HLA-B57 on HCV genotype 2 infection in a West African population
Chuang WC, et al.
J Med Virol 2007 Jun;79(6):724-33

 

Neoplasms

Do thymidylate synthase gene promoter polymorphism and the C/G single nucleotide polymorphism predict effectiveness of adjuvant 5-fluorouracil-based chemotherapy in stage III colonic adenocarcinoma?
Prall F, et al.
Oncol Rep 2007 Jul;18(1):203-9

Expression and gene polymorphisms of the chemokine CXCL5 in colorectal cancer patients
Dimberg J, et al.
Int J Oncol 2007 Jul;31(1):97-102

Association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in New York
Steenport M, et al.
Oncol Rep 2007 Jul;18(1):235-40

A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women
Zubor P, et al.
Oncol Rep 2007 Jul;18(1):211-7

MDM2 polymorphism, survival, and histology in early-stage non-small-cell lung cancer
Heist RS, et al.
J Clin Oncol 2007 Jun;25(16):2243-7

Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers
Choi JY, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1115-20

MDR1 Gene Variants, Indoor Insecticide Exposure, and the Risk of Childhood Acute Lymphoblastic Leukemia
Urayama KY, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1172-7

Association between Germline Variation in the FHIT Gene and Prostate Cancer in Caucasians and African Americans
Levin AM, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1294-7

Associations between Smoking, Polymorphisms in Polycyclic Aromatic Hydrocarbon (PAH) Metabolism and Conjugation Genes and PAH-DNA Adducts in Prostate Tumors Differ by Race
Nock NL, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1236-45

No association exists between E-cadherin gene polymorphism and tumor recurrence in patients with hepatocellular carcinoma after transplantation
Li XD, et al.
Hepatobiliary Pancreat Dis Int 2007 Jun;6(3):254-8

Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer
Temam S, et al.
J Clin Oncol 2007 Jun;25(16):2164-70

Allergy-Related Polymorphisms Influence Glioma Status and Serum IgE Levels
Wiemels JL, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1229-35

Single Nucleotide Polymorphisms in the Promoter Region of the E-cadherin Gene in Gastric Cancer: Case-Control Study in a Young Mexican Population
Medina-Franco H, et al.
Ann Surg Oncol 2007 Jun

Genetic polymorphism of CYP2D6 influences susceptibility to papillary thyroid cancer
Lemos MC, et al.
Clin Endocrinol (Oxf) 2007 Jun

The Angiotensin II/Angiotensin II Receptor System Correlates with Nodal Spread in Intestinal Type Gastric Cancer
Rocken C, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1206-12

Association of polymorphisms in one-carbon metabolism genes and postmenopausal breast cancer incidence
Stevens VL, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1140-7

Mutations of the PIK3CA gene in hereditary colorectal cancers
Miyaki M, et al.
Int J Cancer 2007 Jun

Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese
Xu E, et al.
Mol Carcinog 2007 Jun

Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in bangladesh
Ahsan H, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1270-8

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy
Ruzzo A, et al.
Pharmacogenomics J 2007 Jun

A Comparison of the Pharmacokinetics and Pharmacodynamics of Docetaxel between African-American and Caucasian Cancer Patients: CALGB 9871
Lewis LD, et al.
Clin Cancer Res 2007 Jun;13(11):3302-11

P53 codon 72 polymorphism and gastric cancer: A meta-analysis of the literature
Zhou Y, et al.
Int J Cancer 2007 Jun

Polymorphisms involved in the folate metabolizing pathway and risk of multiple myeloma
Kim HN, et al.
Am J Hematol 2007 Jun

Genetic Variation in H2AFX Contributes to Risk of Non-Hodgkin Lymphoma
Novik KL, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1098-106

 

Endocrine, Nutritional and Metabolic Diseases

MGEA5-14 polymorphism and type 2 diabetes in Mexico City
Cameron EA, et al.
Am J Hum Biol 2007 Jun;19(4):593-6

The Leu544Ile polymorphism of the growth hormone receptor gene affects the serum cholesterol levels during GH treatment in children with GH deficiency
Ihara K, et al.
Clin Endocrinol (Oxf) 2007 Jun

Multiplex ARMS analysis to detect 13 common mutations in familial hypercholesterolaemia
Taylor A, et al.
Clin Genet 2007 Jun;71(6):561-8

Incidence of cystic fibrosis in five different states of Brazil as determined by screening of p.F508del, mutation at the CFTR gene in newborns and patients
Raskin S, et al.
J Cyst Fibros 2007 Jun

Relationship between angiotensin-converting enzyme gene insertion or deletion polymorphism and insulin sensitivity in healthy newborns
Han T, et al.
Pediatrics 2007 Jun;119(6):1089-94

Angiotensin-converting enzyme gene polymorphism and stroke in type 2 diabetic patients in Taiwan
Tseng CH, et al.
Eur J Clin Invest 2007 Jun;37(6):483-91

 

Mental Disorders

Interactive Effects of Sex and 5-HTTLPR on Mood and Impulsivity During Tryptophan Depletion in Healthy People
Walderhaug E, et al.
Biol Psychiatry 2007 Jun

Association Between Treatment-Emergent Suicidal Ideation With Citalopram and Polymorphisms Near Cyclic Adenosine Monophosphate Response Element Binding Protein in the STAR*D Study
Perlis RH, et al.
Arch Gen Psychiatry 2007 Jun;64(6):689-97

Allelic and genotypic associations of DRD2 TaqI A polymorphism with heroin dependence in Spanish subjects: a case control study
Perez de Los Cobos J, et al.
Behav Brain Funct 2007 Jun;3(1):25

Association of COMT Val108/158Met Genotype with Smoking Cessation in a Nicotine Replacement Therapy Randomized Trial
Johnstone EC, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1065-9

 

Diseases of the Nervous System and Sense Organs

FMR1 alleles in Parkinson's disease: relation to cognitive decline and hallucinations, a longitudinal study
Kurz MW, et al.
J Geriatr Psychiatry Neurol 2007 Jun;20(2):89-92

COMT genotype increases risk for bipolar I disorder and influences neurocognitive performance
Burdick KE, et al.
Bipolar Disord 2007 Jun;9(4):370-6

Association study of a functional variant in intron 8 of the dopamine transporter gene and migraine susceptibility
McCallum LK, et al.
Eur J Neurol 2007 Jun;14(6):706-7

Polymorphisms at codons 129 and 219 of the prion protein gene (PRNP) are not associated with sporadic Alzheimer's disease in the Korean population
Jeong BH, et al.
Eur J Neurol 2007 Jun;14(6):621-6

Gender, genotype, and phenotype differences in Smith-Magenis syndrome: a meta-analysis of 105 cases
Edelman E, et al.
Clin Genet 2007 Jun;71(6):540-50

Association of polymorphisms in vascular endothelial growth factor gene with the age of onset of amyotrophic lateral sclerosis
Chen D, et al.
Amyotroph Lateral Scler 2007 Jun;8(3):144-9

Testing association for markers on the X chromosome
Zheng G, et al.
Genet Epidemiol 2007 Jun

The Effects of Prolonged Stress and APOE Genotype on Memory and Cortisol in Older Adults
Peavy GM, et al.
Biol Psychiatry 2007 Jun

Correlations Between Apolipoprotein E {epsilon}4 Gene Dose and Whole Brain Atrophy Rates
Chen K, et al.
Am J Psychiatry 2007 Jun;164(6):916-21

What is the relationship among atherosclerosis markers, apolipoprotein E polymorphism and dementia?
Altamura C, et al.
Eur J Neurol 2007 Jun;14(6):679-82

 

Diseases of the Circulatory System

FV Leiden mutation and risk of recurrent venous thromboembolism in Serbian population
Kovac M, et al.
J Thromb Thrombolysis 2007 Jun

Recurrent In-Stent Restenosis is Not Associated with the Angiotensin-Converting Enzyme D/I, Angiotensinogen Thr174Met and Met235Thr, and the Angiotensin-II Receptor 1 A1166C Polymorphism
Gross CM, et al.
J Invasive Cardiol 2007 Jun;19(6):261-4

In patients chronically treated with metoprolol, the demand of inotropic catecholamine support after coronary artery bypass grafting is determined by the Arg389Gly-beta(1)-adrenoceptor polymorphism
Leineweber K, et al.
Naunyn Schmiedebergs Arch Pharmacol 2007 Jun

Interleukin-4 C-590T Polymorphism Has No Role in Coronary Artery Bypass Surgery
Bittar MN, et al.
Asian Cardiovasc Thorac Ann 2007 Jun;15(3):214-7

Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians
Doolan A, et al.
Int J Cardiol 2007 Jun

Polymorphisms and vascular cognitive impairment after ischemic stroke
Baum L, et al.
J Geriatr Psychiatry Neurol 2007 Jun;20(2):93-9

Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans
Watzka M, et al.
Thromb Haemost 2007 Jun;97(6):998-1002

Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis. A meta-analysis
Tsantes AE, et al.
Thromb Haemost 2007 Jun;97(6):907-13

The hepatic lipase gene C-480T polymorphism in the development of early coronary atherosclerosis: the Helsinki Sudden Death Study
Fan YM, et al.
Eur J Clin Invest 2007 Jun;37(6):472-7

P-selectin glycoprotein ligand-1 VNTR polymorphisms and risk of thrombosis in the antiphospholipid syndrome
Diz-Kucukkaya R, et al.
Ann Rheum Dis 2007 Jun

 

Diseases of the Respiratory System

No Association between Coding Polymorphism within Exon 4 of the Human Surfactant Protein B Gene and Pulmonary Function in Healthy Men
Raleigh SM, et al.
J Physiol Sci 2007 Jun

The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing Chinese
Ng MW, et al.
BMC Infect Dis 2007 Jun;7(1):50

 

Diseases of the Digestive System

A Polymorphism of microRNA 27a Genome Region Is Associated With the Development of Gastric Mucosal Atrophy in Japanese Male Subjects
Arisawa T, et al.
Dig Dis Sci 2007 Jul;52(7):1691-7

Genetic polymorphisms of manganese-superoxide dismutase and glutathione-S-transferase in chronic alcoholic pancreatitis
Osterreicher CH, et al.
Mutagenesis 2007 Jun

Spectrum of mutations and variants/haplotypes of CFTR and genotype-phenotype correlation in idiopathic chronic pancreatitis and controls in Chinese by complete analysis
Chang MC, et al.
Clin Genet 2007 Jun;71(6):530-9

 

Complications of Pregnancy, Childbirth, and the Puerperium

Absence of an association of tumor necrosis factor (TNF)-alpha G308A, interleukin-6 (IL-6) G174C and interleukin-10 (IL-10) G1082A polymorphism in women with preeclampsia
Stonek F, et al.
J Reprod Immunol 2007 Jun

 

Diseases of the Musculoskeletal System and Connective Tissue

Meta-analysis of HLA-DRB1 polymorphism in Latin American patients with rheumatoid arthritis
Delgado-Vega AM & Anaya JM
Autoimmun Rev 2007 Jun;6(6):402-8

 

Symptoms, Signs and Ill-defined Conditions

Variations in RANK gene are associated with adult height in Caucasians
Chen Y, et al.
Am J Hum Biol 2007 Jun;19(4):559-65

Common genetic variation in eight genes of the GH/IGF1 axis does not contribute to adult height variation
Lettre G, et al.
Hum Genet 2007 Jun

 

Injury and Poisoning

Path Analysis of Biomarkers of Exposure and Early Biological Effects among Coke-Oven Workers Exposed to Polycyclic Aromatic Hydrocarbons
Qiu L, et al.
Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1193-9

 

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Page last reviewed: June 7, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics